SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t6o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 3t6o SULFATE
TRANSPORTER/ANTISIGM
A-FACTOR ANTAGONIST
STAS
(Planctopirus
limnophila) 		3 / 3 VAL A  48
TRP A  70
TRP A 103
 None
 1.42A 1c4dA-3t6oA:
undetectable
1c4dB-3t6oA:
undetectable		 1c4dA-3t6oA:
17.95
1c4dB-3t6oA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 3t6o SULFATE
TRANSPORTER/ANTISIGM
A-FACTOR ANTAGONIST
STAS
(Planctopirus
limnophila) 		5 / 12 PHE A  17
ILE A  32
THR A  97
LEU A  83
ILE A  50
 None
 1.22A 1kqwA-3t6oA:
undetectable		 1kqwA-3t6oA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 3t6o SULFATE
TRANSPORTER/ANTISIGM
A-FACTOR ANTAGONIST
STAS
(Planctopirus
limnophila) 		4 / 7 LEU A  52
PHE A  21
PHE A  62
ILE A  50
 None
 0.56A 2opxA-3t6oA:
undetectable		 2opxA-3t6oA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 3t6o SULFATE
TRANSPORTER/ANTISIGM
A-FACTOR ANTAGONIST
STAS
(Planctopirus
limnophila) 		5 / 10 VAL A  48
PHE A  81
ALA A  39
THR A  35
ILE A   4
 None
 1.05A 3t3qA-3t6oA:
undetectable		 3t3qA-3t6oA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3t6o SULFATE
TRANSPORTER/ANTISIGM
A-FACTOR ANTAGONIST
STAS
(Planctopirus
limnophila) 		5 / 10 VAL A  48
PHE A  81
ALA A  39
THR A  35
ILE A   4
 None
 1.11A 3t3qB-3t6oA:
undetectable		 3t3qB-3t6oA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3t6o SULFATE
TRANSPORTER/ANTISIGM
A-FACTOR ANTAGONIST
STAS
(Planctopirus
limnophila) 		5 / 10 VAL A  48
PHE A  81
ALA A  39
THR A  35
ILE A   4
 None
 1.10A 3t3qD-3t6oA:
undetectable		 3t3qD-3t6oA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 3t6o SULFATE
TRANSPORTER/ANTISIGM
A-FACTOR ANTAGONIST
STAS
(Planctopirus
limnophila) 		4 / 8 VAL A  48
TYR A 106
CYH A  84
ILE A  15
 None
 1.02A 4afgD-3t6oA:
undetectable
4afgE-3t6oA:
undetectable		 4afgD-3t6oA:
22.07
4afgE-3t6oA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3t6o SULFATE
TRANSPORTER/ANTISIGM
A-FACTOR ANTAGONIST
STAS
(Planctopirus
limnophila) 		5 / 12 ALA A  33
PHE A  17
LEU A  49
VAL A  48
VAL A  55
 None
 1.22A 4ib4A-3t6oA:
undetectable		 4ib4A-3t6oA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3t6o SULFATE
TRANSPORTER/ANTISIGM
A-FACTOR ANTAGONIST
STAS
(Planctopirus
limnophila) 		5 / 12 ILE A   4
PHE A  36
THR A   7
GLU A   9
ASP A  51
 None
None
CL  A 119 (-4.4A)
None
None
 1.16A 5lg3J-3t6oA:
undetectable		 5lg3J-3t6oA:
18.15