SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t6s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 3t6s CERJ
(Streptomyces
tendae) 		3 / 3 TRP A   3
ALA A 251
VAL A 182
 None
 0.99A 1bdwA-3t6sA:
undetectable
1bdwB-3t6sA:
undetectable		 1bdwA-3t6sA:
14.46
1bdwB-3t6sA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 8 LEU A  80
ALA A 140
LEU A 308
LEU A 305
 None
 0.90A 1dvtA-3t6sA:
undetectable
1dvtB-3t6sA:
undetectable		 1dvtA-3t6sA:
16.20
1dvtB-3t6sA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_A_CAMA503_0
(CYTOCHROME P450-CAM)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 9 TYR A 289
THR A 293
LEU A  15
THR A 144
ASP A 300
 None
 1.26A 1dz8A-3t6sA:
undetectable		 1dz8A-3t6sA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 8 TYR A 289
THR A 293
LEU A  15
ASP A 300
 None
 1.13A 1dz9A-3t6sA:
undetectable		 1dz9A-3t6sA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 8 TYR A 289
THR A 293
LEU A  15
THR A 144
 None
 1.04A 1dz9A-3t6sA:
undetectable		 1dz9A-3t6sA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 6 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 1.05A 1ictB-3t6sA:
undetectable		 1ictB-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 9 LEU A  80
GLY A 121
THR A 185
LEU A   6
LEU A 173
 None
 1.13A 1nr6A-3t6sA:
undetectable		 1nr6A-3t6sA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 10 TYR A 289
THR A 293
LEU A  15
THR A 144
ASP A 300
 None
 1.23A 1o76A-3t6sA:
undetectable		 1o76A-3t6sA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 8 TYR A 289
THR A 293
LEU A  15
THR A 144
 None
 1.05A 1o76B-3t6sA:
undetectable		 1o76B-3t6sA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 11 ALA A 169
THR A  44
VAL A 296
ALA A 102
VAL A  98
 None
 1.17A 1rv7A-3t6sA:
undetectable
1rv7B-3t6sA:
undetectable		 1rv7A-3t6sA:
13.73
1rv7B-3t6sA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 6 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.94A 1tyrA-3t6sA:
undetectable		 1tyrA-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 8 TYR A 289
THR A 293
LEU A  15
ASP A 300
 None
 1.13A 1uyuA-3t6sA:
undetectable		 1uyuA-3t6sA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 8 TYR A 289
THR A 293
LEU A  15
THR A 144
 None
 1.12A 1uyuA-3t6sA:
undetectable		 1uyuA-3t6sA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 8 TYR A 289
THR A 293
LEU A  15
ASP A 300
 None
 1.11A 1uyuB-3t6sA:
undetectable		 1uyuB-3t6sA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 8 TYR A 289
THR A 293
LEU A  15
THR A 144
 None
 1.13A 1uyuB-3t6sA:
undetectable		 1uyuB-3t6sA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 6 ARG A 152
SER A 158
GLY A 217
THR A 218
 None
 0.97A 2f7fA-3t6sA:
undetectable		 2f7fA-3t6sA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 3t6s CERJ
(Streptomyces
tendae) 		3 / 3 TRP A   3
ALA A 251
VAL A 182
 None
 0.92A 2izqC-3t6sA:
undetectable
2izqD-3t6sA:
undetectable		 2izqC-3t6sA:
14.46
2izqD-3t6sA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 9 GLY A 178
LEU A   6
SER A 174
LEU A 130
ASP A 177
 None
 1.44A 2j2pB-3t6sA:
undetectable
2j2pC-3t6sA:
undetectable		 2j2pB-3t6sA:
20.06
2j2pC-3t6sA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 3t6s CERJ
(Streptomyces
tendae) 		6 / 12 SER A  82
ALA A 122
GLY A 121
GLY A 118
ASN A 117
GLY A 324
 None
 1.18A 2pkmA-3t6sA:
undetectable		 2pkmA-3t6sA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 3t6s CERJ
(Streptomyces
tendae) 		6 / 12 SER A  82
ALA A 122
GLY A 121
GLY A 118
ASN A 117
GLY A 325
 None
 1.32A 2pkmA-3t6sA:
undetectable		 2pkmA-3t6sA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 3t6s CERJ
(Streptomyces
tendae) 		3 / 3 GLY A 178
ASP A 177
SER A 174
 None
 0.54A 2qhfA-3t6sA:
undetectable		 2qhfA-3t6sA:
26.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 6 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 1.04A 2roxB-3t6sA:
undetectable		 2roxB-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 9 ALA A  49
ALA A  53
GLY A 167
SER A  47
ALA A  46
 None
 1.43A 2vh3A-3t6sA:
undetectable		 2vh3A-3t6sA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 6 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 1.04A 3cfqA-3t6sA:
undetectable		 3cfqA-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 7 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.90A 3cfqA-3t6sA:
undetectable
3cfqB-3t6sA:
undetectable		 3cfqA-3t6sA:
16.48
3cfqB-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 12 GLY A 328
GLY A 121
GLY A 118
GLY A 326
LEU A  80
 None
 0.79A 3eluA-3t6sA:
undetectable		 3eluA-3t6sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 12 GLY A 328
GLY A 121
GLY A 118
GLY A 326
LEU A  80
 None
 0.82A 3elwA-3t6sA:
undetectable		 3elwA-3t6sA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 3t6s CERJ
(Streptomyces
tendae) 		3 / 3 TRP A   3
ALA A 251
VAL A 182
 None
 0.94A 3l8lC-3t6sA:
undetectable
3l8lD-3t6sA:
undetectable		 3l8lC-3t6sA:
14.46
3l8lD-3t6sA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 7 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.89A 3ozkB-3t6sA:
undetectable		 3ozkB-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 9 ASN A 117
GLY A 325
GLY A 324
PHE A 323
GLY A 326
 None
 1.13A 3ztvA-3t6sA:
undetectable		 3ztvA-3t6sA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_A_TCWA1126_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 6 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.87A 4d7bB-3t6sA:
undetectable		 4d7bB-3t6sA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 9 ASN A 117
GLY A 325
GLY A 324
PHE A 323
GLY A 326
 None
 1.25A 4h2fA-3t6sA:
undetectable		 4h2fA-3t6sA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 11 ALA A 186
LEU A 321
PHE A 323
LEU A 274
THR A 185
 None
 1.38A 4i1nA-3t6sA:
undetectable		 4i1nA-3t6sA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 6 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.96A 4i89A-3t6sA:
undetectable		 4i89A-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 8 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.82A 4ik7B-3t6sA:
undetectable		 4ik7B-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 6 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.81A 4ikiB-3t6sA:
undetectable		 4ikiB-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 7 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.94A 4ikjA-3t6sA:
undetectable
4ikjB-3t6sA:
undetectable		 4ikjA-3t6sA:
16.48
4ikjB-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 7 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.90A 4ikkA-3t6sA:
undetectable
4ikkB-3t6sA:
undetectable		 4ikkA-3t6sA:
16.48
4ikkB-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3t6s CERJ
(Streptomyces
tendae) 		6 / 12 ALA A 303
GLY A 145
GLY A 297
ASP A 146
LEU A  84
ALA A 169
 None
 1.02A 4lg1A-3t6sA:
undetectable		 4lg1A-3t6sA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 12 ALA A 303
GLY A 145
GLY A 297
LEU A  84
ALA A 169
 None
 0.86A 4lg1B-3t6sA:
undetectable		 4lg1B-3t6sA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3t6s CERJ
(Streptomyces
tendae) 		6 / 12 ALA A 303
GLY A 145
GLY A 297
ASP A 146
LEU A  84
ALA A 169
 None
 1.04A 4lg1C-3t6sA:
undetectable		 4lg1C-3t6sA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 12 GLY A 299
ALA A 298
GLY A 297
LEU A  84
GLY A 167
 None
 0.93A 4o3fA-3t6sA:
undetectable		 4o3fA-3t6sA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 7 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.86A 4pwjB-3t6sA:
undetectable		 4pwjB-3t6sA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 10 ALA A 303
ALA A 168
ALA A  13
GLY A 294
THR A 293
 None
 1.03A 4qvyK-3t6sA:
undetectable
4qvyL-3t6sA:
undetectable		 4qvyK-3t6sA:
19.83
4qvyL-3t6sA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 10 ALA A 303
ALA A 168
ALA A  13
GLY A 294
THR A 293
 None
 1.02A 4qvyY-3t6sA:
undetectable
4qvyZ-3t6sA:
undetectable		 4qvyY-3t6sA:
19.83
4qvyZ-3t6sA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 3t6s CERJ
(Streptomyces
tendae) 		3 / 3 PHE A 179
THR A 185
LEU A 171
 None
 0.63A 4qztA-3t6sA:
undetectable		 4qztA-3t6sA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 12 THR A 175
GLY A 135
GLY A 133
GLY A 131
ALA A 136
 None
 1.02A 4uciB-3t6sA:
undetectable		 4uciB-3t6sA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA907_0
(PROTEIN ARGONAUTE-2)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 5 ALA A  61
THR A 144
THR A 143
TYR A 302
 None
 1.47A 4w5oA-3t6sA:
0.0		 4w5oA-3t6sA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 6 ALA A  61
THR A 144
THR A 143
TYR A 302
 None
 1.44A 4w5qA-3t6sA:
undetectable		 4w5qA-3t6sA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 6 ALA A  61
THR A 144
THR A 143
TYR A 302
 None
 1.48A 4w5tA-3t6sA:
undetectable		 4w5tA-3t6sA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3t6s CERJ
(Streptomyces
tendae) 		3 / 4 ARG A 268
GLY A 271
GLU A 273
 None
 0.58A 4z2dB-3t6sA:
undetectable
4z2dC-3t6sA:
undetectable		 4z2dB-3t6sA:
24.06
4z2dC-3t6sA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 5 ALA A  61
THR A 144
THR A 143
TYR A 302
 None
 1.47A 4z4dA-3t6sA:
0.0		 4z4dA-3t6sA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA907_0
(PROTEIN ARGONAUTE-2)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 5 ALA A  61
THR A 144
THR A 143
TYR A 302
 None
 1.46A 4z4eA-3t6sA:
0.0		 4z4eA-3t6sA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 6 ALA A  61
THR A 144
THR A 143
TYR A 302
 None
 1.44A 4z4fA-3t6sA:
undetectable		 4z4fA-3t6sA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 6 ALA A  61
THR A 144
THR A 143
TYR A 302
 None
 1.44A 4z4iA-3t6sA:
undetectable		 4z4iA-3t6sA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 6 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.96A 5bojA-3t6sA:
undetectable		 5bojA-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 7 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.93A 5bojB-3t6sA:
undetectable		 5bojB-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 7 ASP A 257
ARG A 319
GLY A 317
GLU A 337
 None
 1.03A 5bs8A-3t6sA:
undetectable
5bs8B-3t6sA:
undetectable
5bs8C-3t6sA:
undetectable		 5bs8A-3t6sA:
21.79
5bs8B-3t6sA:
22.50
5bs8C-3t6sA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 7 ASP A 257
ARG A 319
GLY A 317
GLU A 337
 None
 1.08A 5btfA-3t6sA:
undetectable
5btfC-3t6sA:
undetectable
5btfD-3t6sA:
undetectable		 5btfA-3t6sA:
21.79
5btfC-3t6sA:
21.79
5btfD-3t6sA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 6 LEU A 240
ALA A 243
LEU A 239
THR A 187
 None
 0.91A 5l4iA-3t6sA:
undetectable		 5l4iA-3t6sA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 7 VAL A 336
ILE A 338
VAL A   8
ALA A 180
 None
 0.68A 5ospA-3t6sA:
undetectable		 5ospA-3t6sA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3t6s CERJ
(Streptomyces
tendae) 		4 / 7 VAL A 336
ILE A 338
VAL A   8
ALA A 180
 None
 0.65A 5osrA-3t6sA:
undetectable		 5osrA-3t6sA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 3t6s CERJ
(Streptomyces
tendae) 		5 / 12 SER A  82
TYR A 302
ILE A 123
LEU A 173
LEU A  78
 None
 1.44A 5zwrB-3t6sA:
undetectable		 5zwrB-3t6sA:
24.02