SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		3 / 3 TRP A 268
VAL A 271
TRP A 275
 None
 0.97A 1c4dA-3t79A:
undetectable
1c4dB-3t79A:
undetectable		 1c4dA-3t79A:
2.24
1c4dB-3t79A:
2.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_A_BEZA1501_0
(RAS-RELATED PROTEIN
RAB-9A)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		4 / 5 ILE A 109
TRP A 268
LEU A 261
PRO A 262
 None
 1.39A 1s8fA-3t79A:
undetectable
1s8fB-3t79A:
undetectable		 1s8fA-3t79A:
18.09
1s8fB-3t79A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		3 / 3 ASN A 272
TRP A 275
GLN A 273
 None
 1.44A 1xoqA-3t79A:
undetectable		 1xoqA-3t79A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		3 / 3 THR A  15
THR A  13
PRO A  12
 None
 0.87A 209dC-3t79A:
undetectable		 209dC-3t79A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		4 / 7 SER A 294
ASP A 169
LEU A 315
GLU A 308
 None
 1.09A 2cdqB-3t79A:
undetectable		 2cdqB-3t79A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		3 / 3 PRO A 198
THR A 196
PRO A 194
 None
 0.85A 2d55C-3t79A:
undetectable		 2d55C-3t79A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		4 / 8 VAL A 159
THR A 158
ASP A 142
ILE A 234
 None
 0.90A 2qbmA-3t79A:
undetectable		 2qbmA-3t79A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		5 / 12 LEU A 208
LEU A 137
LEU A 140
GLN A 144
LEU A 345
 None
 1.45A 3d90A-3t79A:
undetectable		 3d90A-3t79A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		5 / 12 MET A  71
ALA A  77
LEU A   4
LEU A   7
LEU A  11
 None
 1.17A 3erdA-3t79A:
undetectable		 3erdA-3t79A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		5 / 6 LEU A 340
SER A 343
ILE A 199
CYH A 197
PHE A 195
 None
 1.49A 3ko0B-3t79A:
0.0		 3ko0B-3t79A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		5 / 11 LEU A 340
SER A 343
ILE A 199
CYH A 197
PHE A 195
 None
 1.49A 3ko0A-3t79A:
undetectable
3ko0B-3t79A:
0.0
3ko0C-3t79A:
undetectable
3ko0D-3t79A:
undetectable		 3ko0A-3t79A:
13.68
3ko0B-3t79A:
13.68
3ko0C-3t79A:
13.68
3ko0D-3t79A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		5 / 11 ASP A 170
LEU A 177
LEU A 341
SER A 343
ILE A 199
 None
 1.26A 3ko0A-3t79A:
undetectable
3ko0B-3t79A:
undetectable
3ko0I-3t79A:
undetectable
3ko0J-3t79A:
undetectable		 3ko0A-3t79A:
13.68
3ko0B-3t79A:
13.68
3ko0I-3t79A:
13.68
3ko0J-3t79A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		5 / 11 LEU A 340
SER A 343
ILE A 199
CYH A 197
PHE A 195
 None
 1.46A 3ko0O-3t79A:
undetectable
3ko0P-3t79A:
undetectable
3ko0Q-3t79A:
undetectable
3ko0R-3t79A:
undetectable		 3ko0O-3t79A:
13.68
3ko0P-3t79A:
13.68
3ko0Q-3t79A:
13.68
3ko0R-3t79A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		5 / 10 LEU A 340
SER A 343
ILE A 199
CYH A 197
PHE A 195
 None
 1.46A 3ko0O-3t79A:
undetectable
3ko0P-3t79A:
undetectable
3ko0Q-3t79A:
undetectable
3ko0R-3t79A:
undetectable		 3ko0O-3t79A:
13.68
3ko0P-3t79A:
13.68
3ko0Q-3t79A:
13.68
3ko0R-3t79A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		5 / 10 LEU A  88
LYS A  48
VAL A  51
ILE A  54
ILE A  22
 None
 1.39A 3kz7A-3t79A:
undetectable		 3kz7A-3t79A:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		4 / 8 PRO A 317
SER A 343
LEU A 340
ASP A 339
 None
 1.00A 3lsfH-3t79A:
undetectable		 3lsfH-3t79A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		3 / 3 TYR A  53
ASP A  59
ASP A  63
 None
 0.87A 4a6eA-3t79A:
undetectable		 4a6eA-3t79A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		3 / 3 PHE A 191
THR A 299
LEU A 340
 None
 0.61A 4qztA-3t79A:
undetectable		 4qztA-3t79A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_D_ACTD406_0
(PROTON-GATED ION
CHANNEL)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		4 / 4 ILE A 233
ILE A 231
ARG A 235
TYR A 206
 None
 1.48A 4zzcD-3t79A:
1.2		 4zzcD-3t79A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		4 / 6 ILE A 361
LEU A 367
PHE A 362
THR A 347
 None
 1.03A 5b1aN-3t79A:
undetectable
5b1aW-3t79A:
undetectable		 5b1aN-3t79A:
20.72
5b1aW-3t79A:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		3 / 3 VAL A  96
GLN A  89
CYH A  68
 None
 0.85A 5icxC-3t79A:
undetectable
5icxF-3t79A:
undetectable		 5icxC-3t79A:
19.49
5icxF-3t79A:
6.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3t79 KLLA0E03807P
(Kluyveromyces
lactis) 		5 / 12 ASN A 311
PRO A 198
ILE A 199
ILE A 307
PHE A 185
 None
 1.47A 6j21A-3t79A:
undetectable		 6j21A-3t79A:
20.61