SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t7y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3t7y YOP PROTEINS
TRANSLOCATION
PROTEIN U
(Chlamydia
trachomatis) 		3 / 3 SER A 257
ALA A 269
VAL A 268
 None
 0.55A 4o2bA-3t7yA:
undetectable		 4o2bA-3t7yA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3t7y YOP PROTEINS
TRANSLOCATION
PROTEIN U
(Chlamydia
trachomatis) 		3 / 3 SER A 257
ALA A 269
VAL A 268
 None
 0.57A 4x1iA-3t7yA:
undetectable		 4x1iA-3t7yA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3t7y YOP PROTEINS
TRANSLOCATION
PROTEIN U
(Chlamydia
trachomatis) 		3 / 3 SER A 257
ALA A 269
VAL A 268
 None
 0.55A 5eypA-3t7yA:
undetectable		 5eypA-3t7yA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9Y_A_1N1A1001_2
(EPHRIN TYPE-A
RECEPTOR 2)		 3t7y YOP PROTEINS
TRANSLOCATION
PROTEIN U
(Chlamydia
trachomatis) 		3 / 3 ILE A 336
ILE A 325
MET A 306
 None
 0.70A 5i9yA-3t7yA:
undetectable		 5i9yA-3t7yA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3t7y YOP PROTEINS
TRANSLOCATION
PROTEIN U
(Chlamydia
trachomatis) 		5 / 10 ILE A 270
ILE A 282
VAL A 333
THR A 329
GLU A 318
 None
 1.19A 5lg3G-3t7yA:
undetectable		 5lg3G-3t7yA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3t7y YOP PROTEINS
TRANSLOCATION
PROTEIN U
(Chlamydia
trachomatis) 		5 / 10 ILE A 270
ILE A 282
VAL A 333
THR A 329
GLU A 318
 None
 1.18A 5lg3H-3t7yA:
undetectable		 5lg3H-3t7yA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3t7y YOP PROTEINS
TRANSLOCATION
PROTEIN U
(Chlamydia
trachomatis) 		5 / 12 ILE A 270
ILE A 282
VAL A 333
THR A 329
GLU A 318
 None
 1.21A 5lg3J-3t7yA:
undetectable		 5lg3J-3t7yA:
14.92