SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t9n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 3t9n SMALL-CONDUCTANCE
MECHANOSENSITIVE
CHANNEL
(Caldanaerobacter
subterraneus) 		4 / 8 PHE A 188
VAL A 256
VAL A 221
VAL A 236
 None
 0.94A 1iwiA-3t9nA:
undetectable		 1iwiA-3t9nA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 3t9n SMALL-CONDUCTANCE
MECHANOSENSITIVE
CHANNEL
(Caldanaerobacter
subterraneus) 		5 / 11 GLY A  81
ALA A  80
ILE A  30
ILE A  75
ILE A  35
 None
 1.09A 3ebzB-3t9nA:
undetectable		 3ebzB-3t9nA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 3t9n SMALL-CONDUCTANCE
MECHANOSENSITIVE
CHANNEL
(Caldanaerobacter
subterraneus) 		4 / 7 GLY A 167
ILE A 169
ASN A 138
GLN A 111
 None
 0.85A 4g0vA-3t9nA:
undetectable		 4g0vA-3t9nA:
17.66