SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3t9w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 193
ALA A 287
SER A 282
HIS A 281
 NI  A 307 (-3.6A)
None
None
CU  A 311 (-3.1A)
 1.27A 1errA-3t9wA:
undetectable
1errB-3t9wA:
undetectable		 1errA-3t9wA:
21.14
1errB-3t9wA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 4 VAL A 207
TRP A 272
TRP A 209
 None
 1.37A 1gmkC-3t9wA:
undetectable
1gmkD-3t9wA:
undetectable		 1gmkC-3t9wA:
5.16
1gmkD-3t9wA:
5.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 ALA A 138
VAL A 166
TRP A  70
 None
 0.96A 1grmA-3t9wA:
undetectable		 1grmA-3t9wA:
5.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 ALA A 138
VAL A 166
TRP A  70
 None
 0.96A 1grmB-3t9wA:
undetectable		 1grmB-3t9wA:
5.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 4 HIS A 219
CYH A 276
HIS A 281
MET A 286
 CU  A 311 (-3.1A)
CU  A 311 (-2.1A)
CU  A 311 (-3.1A)
CU  A 311 (-3.3A)
 0.51A 1oe1A-3t9wA:
21.2		 1oe1A-3t9wA:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 219
CYH A 276
HIS A 281
MET A 286
 CU  A 311 (-3.1A)
CU  A 311 (-2.1A)
CU  A 311 (-3.1A)
CU  A 311 (-3.3A)
 0.50A 1oe2A-3t9wA:
10.3		 1oe2A-3t9wA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 4 HIS A 219
CYH A 276
HIS A 281
MET A 286
 CU  A 311 (-3.1A)
CU  A 311 (-2.1A)
CU  A 311 (-3.1A)
CU  A 311 (-3.3A)
 0.54A 1oe3A-3t9wA:
21.0		 1oe3A-3t9wA:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		5 / 12 ILE A 188
ASP A 185
GLY A 213
GLY A 215
LEU A 251
 None
 0.88A 1rjdA-3t9wA:
undetectable		 1rjdA-3t9wA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		5 / 12 ILE A 188
ASP A 185
GLY A 213
GLY A 215
LEU A 251
 None
 0.87A 1rjdB-3t9wA:
undetectable		 1rjdB-3t9wA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		5 / 12 ILE A 188
ASP A 185
GLY A 213
GLY A 215
LEU A 251
 None
 0.88A 1rjdC-3t9wA:
undetectable		 1rjdC-3t9wA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A  90
HIS A 144
HIS A 146
 None
 0.70A 1rjoA-3t9wA:
undetectable		 1rjoA-3t9wA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_1
(VITAMIN D3 RECEPTOR)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 SER A 108
ARG A 116
HIS A  92
HIS A 144
 None
 0.90A 1s19A-3t9wA:
undetectable		 1s19A-3t9wA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A  90
HIS A 144
HIS A 146
 None
 0.69A 1w2zA-3t9wA:
undetectable		 1w2zA-3t9wA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A  90
HIS A 144
HIS A 146
 None
 0.65A 1w2zB-3t9wA:
undetectable		 1w2zB-3t9wA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A  90
HIS A 144
HIS A 146
 None
 0.66A 1w2zC-3t9wA:
undetectable		 1w2zC-3t9wA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A  90
HIS A 144
HIS A 146
 None
 0.64A 1w2zD-3t9wA:
undetectable		 1w2zD-3t9wA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 4 HIS A 219
CYH A 276
HIS A 281
MET A 286
 CU  A 311 (-3.1A)
CU  A 311 (-2.1A)
CU  A 311 (-3.1A)
CU  A 311 (-3.3A)
 0.46A 2fqdA-3t9wA:
17.3		 2fqdA-3t9wA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 4 HIS A 219
CYH A 276
HIS A 281
MET A 286
 CU  A 311 (-3.1A)
CU  A 311 (-2.1A)
CU  A 311 (-3.1A)
CU  A 311 (-3.3A)
 0.43A 2fqeA-3t9wA:
17.4		 2fqeA-3t9wA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 4 HIS A 219
CYH A 276
HIS A 281
MET A 286
 CU  A 311 (-3.1A)
CU  A 311 (-2.1A)
CU  A 311 (-3.1A)
CU  A 311 (-3.3A)
 0.43A 2fqfA-3t9wA:
17.3		 2fqfA-3t9wA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 4 HIS A 219
CYH A 276
HIS A 281
MET A 286
 CU  A 311 (-3.1A)
CU  A 311 (-2.1A)
CU  A 311 (-3.1A)
CU  A 311 (-3.3A)
 0.45A 2fqgA-3t9wA:
undetectable		 2fqgA-3t9wA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A  90
HIS A 144
HIS A 146
 None
 0.67A 2oqeA-3t9wA:
undetectable		 2oqeA-3t9wA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A  90
HIS A 144
HIS A 146
 None
 0.66A 2oqeB-3t9wA:
undetectable		 2oqeB-3t9wA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A  90
HIS A 144
HIS A 146
 None
 0.67A 2oqeC-3t9wA:
undetectable		 2oqeC-3t9wA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A  90
HIS A 144
HIS A 146
 None
 0.67A 2oqeD-3t9wA:
undetectable		 2oqeD-3t9wA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A  90
HIS A 144
HIS A 146
 None
 0.67A 2oqeF-3t9wA:
undetectable		 2oqeF-3t9wA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 TRP A 228
GLN A 260
TRP A 272
 None
 0.94A 2vqyA-3t9wA:
undetectable		 2vqyA-3t9wA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A  90
HIS A 144
HIS A 146
 None
 0.67A 2w0qB-3t9wA:
undetectable		 2w0qB-3t9wA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		5 / 8 GLY A 102
HIS A  90
ILE A  77
ALA A 147
HIS A 144
 None
 1.45A 2x0pA-3t9wA:
undetectable		 2x0pA-3t9wA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 4 HIS A 219
CYH A 276
HIS A 281
MET A 286
 CU  A 311 (-3.1A)
CU  A 311 (-2.1A)
CU  A 311 (-3.1A)
CU  A 311 (-3.3A)
 0.49A 2xxgA-3t9wA:
10.2		 2xxgA-3t9wA:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 219
CYH A 276
HIS A 281
MET A 286
 CU  A 311 (-3.1A)
CU  A 311 (-2.1A)
CU  A 311 (-3.1A)
CU  A 311 (-3.3A)
 0.51A 2xxgC-3t9wA:
10.2		 2xxgC-3t9wA:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A  92
HIS A 144
HIS A  90
 None
 0.74A 3ag4A-3t9wA:
undetectable		 3ag4A-3t9wA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A 144
HIS A  92
HIS A 142
 None
 0.71A 3ag4A-3t9wA:
undetectable		 3ag4A-3t9wA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A 144
HIS A  92
HIS A 142
 None
 0.76A 3ag4N-3t9wA:
undetectable		 3ag4N-3t9wA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 VAL A 167
VAL A 166
GLN A 260
ARG A 206
 None
 1.39A 3bjwH-3t9wA:
undetectable		 3bjwH-3t9wA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 VAL A 167
VAL A 166
GLN A 260
ARG A 206
 None
 1.37A 3bjwB-3t9wA:
undetectable		 3bjwB-3t9wA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A  90
HIS A 144
HIS A 146
 None
 0.73A 3hiiA-3t9wA:
undetectable		 3hiiA-3t9wA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 GLU A 151
GLY A 153
THR A 154
 None
 0.49A 3iazA-3t9wA:
undetectable		 3iazA-3t9wA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A 275
HIS A 222
HIS A 224
 CU  A 310 ( 3.3A)
CU  A 308 ( 3.4A)
CU  A 310 ( 3.3A)
 0.77A 3mihA-3t9wA:
undetectable		 3mihA-3t9wA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A 275
HIS A 224
MET A 273
 CU  A 310 ( 3.3A)
CU  A 310 ( 3.3A)
CU  A 310 ( 4.4A)
 0.59A 3mihA-3t9wA:
undetectable		 3mihA-3t9wA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 7 VAL A  94
LEU A  89
MET A  41
ILE A  77
 None
 1.01A 3rfmA-3t9wA:
undetectable		 3rfmA-3t9wA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 4 HIS A 219
CYH A 276
HIS A 281
MET A 286
 CU  A 311 (-3.1A)
CU  A 311 (-2.1A)
CU  A 311 (-3.1A)
CU  A 311 (-3.3A)
 0.44A 4ef3A-3t9wA:
3.8		 4ef3A-3t9wA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		5 / 12 ALA A  43
ILE A 212
TYR A 143
LEU A  67
LEU A 165
 None
 1.23A 4l9qB-3t9wA:
undetectable		 4l9qB-3t9wA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 277
HIS A 222
HIS A 275
HIS A 224
 CU  A 309 ( 3.2A)
CU  A 308 ( 3.4A)
CU  A 310 ( 3.3A)
CU  A 310 ( 3.3A)
 0.88A 5mhwA-3t9wA:
10.7		 5mhwA-3t9wA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 277
HIS A 222
HIS A 275
HIS A 224
 CU  A 309 ( 3.2A)
CU  A 308 ( 3.4A)
CU  A 310 ( 3.3A)
CU  A 310 ( 3.3A)
 0.88A 5mhxA-3t9wA:
18.3		 5mhxA-3t9wA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 277
HIS A 222
HIS A 275
HIS A 224
 CU  A 309 ( 3.2A)
CU  A 308 ( 3.4A)
CU  A 310 ( 3.3A)
CU  A 310 ( 3.3A)
 0.88A 5mhyA-3t9wA:
18.3		 5mhyA-3t9wA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 277
HIS A 222
HIS A 275
HIS A 224
 CU  A 309 ( 3.2A)
CU  A 308 ( 3.4A)
CU  A 310 ( 3.3A)
CU  A 310 ( 3.3A)
 0.89A 5mhzA-3t9wA:
18.3		 5mhzA-3t9wA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 277
HIS A 222
HIS A 275
HIS A 224
 CU  A 309 ( 3.2A)
CU  A 308 ( 3.4A)
CU  A 310 ( 3.3A)
CU  A 310 ( 3.3A)
 0.89A 5mi1A-3t9wA:
18.3		 5mi1A-3t9wA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 277
HIS A 222
HIS A 275
HIS A 224
 CU  A 309 ( 3.2A)
CU  A 308 ( 3.4A)
CU  A 310 ( 3.3A)
CU  A 310 ( 3.3A)
 0.88A 5mi2A-3t9wA:
18.3		 5mi2A-3t9wA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 277
HIS A 222
HIS A 275
HIS A 224
 CU  A 309 ( 3.2A)
CU  A 308 ( 3.4A)
CU  A 310 ( 3.3A)
CU  A 310 ( 3.3A)
 0.89A 5miaA-3t9wA:
10.7		 5miaA-3t9wA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 277
HIS A 222
HIS A 275
HIS A 224
 CU  A 309 ( 3.2A)
CU  A 308 ( 3.4A)
CU  A 310 ( 3.3A)
CU  A 310 ( 3.3A)
 0.88A 5mibA-3t9wA:
18.3		 5mibA-3t9wA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 277
HIS A 222
HIS A 275
HIS A 224
 CU  A 309 ( 3.2A)
CU  A 308 ( 3.4A)
CU  A 310 ( 3.3A)
CU  A 310 ( 3.3A)
 0.89A 5micA-3t9wA:
10.7		 5micA-3t9wA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 277
HIS A 222
HIS A 275
HIS A 224
 CU  A 309 ( 3.2A)
CU  A 308 ( 3.4A)
CU  A 310 ( 3.3A)
CU  A 310 ( 3.3A)
 0.89A 5midA-3t9wA:
18.3		 5midA-3t9wA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 277
HIS A 222
HIS A 275
HIS A 224
 CU  A 309 ( 3.2A)
CU  A 308 ( 3.4A)
CU  A 310 ( 3.3A)
CU  A 310 ( 3.3A)
 0.89A 5mieA-3t9wA:
10.7		 5mieA-3t9wA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 HIS A 277
HIS A 222
HIS A 275
HIS A 224
 CU  A 309 ( 3.2A)
CU  A 308 ( 3.4A)
CU  A 310 ( 3.3A)
CU  A 310 ( 3.3A)
 0.88A 5migA-3t9wA:
10.7		 5migA-3t9wA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A  92
HIS A  90
HIS A 146
 None
 1.01A 5oexA-3t9wA:
undetectable		 5oexA-3t9wA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 5 PRO A  65
GLY A  54
TYR A  53
VAL A  62
 None
 1.44A 5x80C-3t9wA:
undetectable
5x80D-3t9wA:
undetectable		 5x80C-3t9wA:
25.98
5x80D-3t9wA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		4 / 6 GLY A  52
ASP A 145
GLY A  64
GLY A 163
 None
 0.77A 6ag0C-3t9wA:
undetectable		 6ag0C-3t9wA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3t9w SMALL LACCASE,
MULTI-COPPER OXIDASE
(Amycolatopsis
sp.
ATCC
39116) 		3 / 3 HIS A 144
HIS A  92
HIS A 142
 None
 0.70A 6giqa-3t9wA:
undetectable		 6giqa-3t9wA:
18.69