SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ta6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 10 LEU A 243
VAL A  43
VAL A 238
GLY A   9
LEU A  15
 None
 1.43A 1fk9A-3ta6A:
undetectable		 1fk9A-3ta6A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 251
ASP A  40
VAL A 233
VAL A 238
ILE A   7
 None
 0.92A 2f8gA-3ta6A:
undetectable		 2f8gA-3ta6A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 156
ALA A 118
ASP A 111
ILE A 195
LEU A 199
 None
 1.19A 2jn3A-3ta6A:
undetectable		 2jn3A-3ta6A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		4 / 7 GLY A 217
ALA A 188
ALA A 183
VAL A 233
 None
 0.77A 3a2qA-3ta6A:
undetectable		 3a2qA-3ta6A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 12 CYH A  93
SER A  94
LEU A 126
THR A 127
ALA A  68
 None
 1.05A 3a35A-3ta6A:
undetectable		 3a35A-3ta6A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 12 CYH A  93
SER A  94
LEU A 126
THR A 127
ALA A  68
 None
 1.04A 3a35B-3ta6A:
undetectable		 3a35B-3ta6A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 12 CYH A  93
SER A  94
LEU A 126
THR A 127
ALA A  68
 None
 1.07A 3a3bA-3ta6A:
undetectable		 3a3bA-3ta6A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 9 LEU A 251
ASP A  40
VAL A 233
VAL A 238
ILE A   7
 None
 0.93A 3oxvA-3ta6A:
undetectable		 3oxvA-3ta6A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 10 LEU A 251
ASP A  40
VAL A 233
VAL A 238
ILE A   7
 None
 0.92A 3oxwD-3ta6A:
undetectable		 3oxwD-3ta6A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		3 / 3 LYS A   4
PRO A   5
LEU A   6
 None
 0.82A 3tpxE-3ta6A:
undetectable		 3tpxE-3ta6A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 239
LEU A 214
GLY A 216
PHE A 248
LEU A 243
 None
 1.07A 3vywC-3ta6A:
undetectable		 3vywC-3ta6A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRK_D_CAMD502_0
(CAMPHOR
5-MONOOXYGENASE)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		4 / 5 PHE A 248
LEU A   6
GLY A 235
VAL A 219
 None
 1.00A 3wrkD-3ta6A:
undetectable		 3wrkD-3ta6A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 156
VAL A 130
LEU A   6
ILE A 169
ALA A 208
 None
 1.09A 4ltwA-3ta6A:
undetectable		 4ltwA-3ta6A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		4 / 4 ALA A 249
ALA A 252
ALA A 253
ALA A 256
 None
 0.13A 4oadA-3ta6A:
undetectable		 4oadA-3ta6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		4 / 4 ALA A 249
ALA A 252
ALA A 253
ALA A 256
 None
 0.12A 4oaeA-3ta6A:
undetectable		 4oaeA-3ta6A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 233
LEU A 199
LEU A 152
ILE A 195
VAL A 130
 None
 0.96A 4y0sA-3ta6A:
undetectable		 4y0sA-3ta6A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A211_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		4 / 6 VAL A 114
LYS A 117
ALA A 118
VAL A 130
 None
 1.02A 5i8fA-3ta6A:
undetectable		 5i8fA-3ta6A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		3 / 3 THR A  65
SER A  94
TYR A  95
 None
 0.85A 5jsdA-3ta6A:
undetectable		 5jsdA-3ta6A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		3 / 3 THR A  65
SER A  94
TYR A  95
 None
 0.85A 5jsdB-3ta6A:
undetectable		 5jsdB-3ta6A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		3 / 3 THR A  65
SER A  94
TYR A  95
 None
 0.85A 5jsdC-3ta6A:
undetectable		 5jsdC-3ta6A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		3 / 3 THR A  65
SER A  94
TYR A  95
 None
 0.86A 5jseA-3ta6A:
undetectable		 5jseA-3ta6A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		3 / 3 THR A  65
SER A  94
TYR A  95
 None
 0.84A 5jseB-3ta6A:
undetectable		 5jseB-3ta6A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		3 / 3 THR A  65
SER A  94
TYR A  95
 None
 0.84A 5jseC-3ta6A:
undetectable		 5jseC-3ta6A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 172
LEU A 214
GLY A 239
ASN A  10
ALA A  42
 None
 1.28A 5kbwA-3ta6A:
undetectable		 5kbwA-3ta6A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 172
LEU A 214
GLY A 239
ASN A  10
ALA A  42
 None
 1.27A 5kbwB-3ta6A:
undetectable		 5kbwB-3ta6A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 172
LEU A 214
GLY A 239
ASN A  10
ALA A  42
 None
 1.26A 5kc0A-3ta6A:
0.0		 5kc0A-3ta6A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 172
LEU A 214
GLY A 239
ASN A  10
ALA A  42
 None
 1.36A 5kc4E-3ta6A:
undetectable		 5kc4E-3ta6A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		6 / 11 LEU A  56
ASP A  58
LEU A  62
THR A  65
LEU A  64
VAL A  24
 None
 1.35A 5twjD-3ta6A:
undetectable		 5twjD-3ta6A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 10 LEU A 243
VAL A  43
VAL A 238
GLY A   9
LEU A  15
 None
 1.34A 6bsgA-3ta6A:
undetectable		 6bsgA-3ta6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 10 LEU A 243
VAL A  43
VAL A 238
GLY A   9
LEU A  15
 None
 1.21A 6bsiA-3ta6A:
undetectable		 6bsiA-3ta6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 10 LEU A 243
VAL A  43
VAL A 238
GLY A   9
LEU A  15
 None
 1.35A 6bsjA-3ta6A:
undetectable		 6bsjA-3ta6A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		4 / 6 GLN A  69
VAL A  96
ALA A 121
THR A 120
 None
 1.04A 6cduB-3ta6A:
undetectable
6cduC-3ta6A:
undetectable		 6cduB-3ta6A:
20.85
6cduC-3ta6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 3ta6 TRIOSEPHOSPHATE
ISOMERASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 251
ASP A  40
VAL A 233
VAL A 238
ILE A   7
 None
 0.91A 6dh6A-3ta6A:
undetectable		 6dh6A-3ta6A:
13.67