SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tad'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 11 PHE C 829
ARG C 822
ALA C 809
LEU C 825
ALA C 826
 None
 1.47A 1jb0B-3tadC:
undetectable		 1jb0B-3tadC:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_B_RBFB502_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 11 ILE C 731
LEU C 729
GLY C 791
SER C 790
LEU C 811
 None
 1.34A 1kyvA-3tadC:
undetectable
1kyvB-3tadC:
undetectable		 1kyvA-3tadC:
20.58
1kyvB-3tadC:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 726
HIS C 727
LEU C 692
GLY C 691
HIS C 793
 None
 1.48A 1v8bA-3tadC:
undetectable		 1v8bA-3tadC:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 726
HIS C 727
LEU C 692
GLY C 691
HIS C 793
 None
 1.48A 1v8bB-3tadC:
undetectable		 1v8bB-3tadC:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 726
HIS C 727
LEU C 692
GLY C 691
HIS C 793
 None
 1.47A 1v8bC-3tadC:
undetectable		 1v8bC-3tadC:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		3 / 3 LEU C 620
HIS C 656
LYS C 659
 None
 1.11A 1y7iA-3tadC:
undetectable		 1y7iA-3tadC:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 729
ALA C 734
GLY C 791
SER C 790
LEU C 811
 None
 1.25A 2a58A-3tadC:
undetectable
2a58B-3tadC:
undetectable		 2a58A-3tadC:
20.58
2a58B-3tadC:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 729
ALA C 734
GLY C 791
SER C 790
LEU C 811
 None
 1.26A 2a58B-3tadC:
undetectable
2a58C-3tadC:
undetectable		 2a58B-3tadC:
20.58
2a58C-3tadC:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 729
ALA C 734
GLY C 791
SER C 790
LEU C 811
 None
 1.25A 2a58D-3tadC:
undetectable
2a58E-3tadC:
undetectable		 2a58D-3tadC:
20.58
2a58E-3tadC:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		5 / 12 LEU A1063
LEU A1054
LEU A1051
ALA A1048
ILE A1024
 None
 1.25A 2bxpA-3tadA:
undetectable		 2bxpA-3tadA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		5 / 12 ILE A 939
TRP A 906
LEU A 907
MET A 913
TYR A 917
 None
 1.11A 2no0A-3tadA:
undetectable		 2no0A-3tadA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		5 / 12 ILE A 943
VAL A 903
TRP A 906
LEU A 907
MET A 913
 None
 1.31A 2no0A-3tadA:
undetectable		 2no0A-3tadA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		5 / 12 ILE A 943
VAL A 903
TRP A 906
LEU A 907
MET A 913
 None
 1.20A 2no0B-3tadA:
undetectable		 2no0B-3tadA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 9 PHE C 829
ARG C 822
ALA C 809
LEU C 825
ALA C 826
 None
 1.42A 2o01B-3tadC:
undetectable		 2o01B-3tadC:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		5 / 12 LEU A 934
LEU A 956
ALA A 957
MET A 913
PHE A 895
 None
 1.43A 2oaxD-3tadA:
undetectable		 2oaxD-3tadA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_1
(DEOXYCYTIDINE KINASE)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		5 / 12 ILE A 939
TRP A 906
LEU A 907
MET A 913
TYR A 917
 None
 1.13A 2ziaB-3tadA:
undetectable		 2ziaB-3tadA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_1
(DEOXYCYTIDINE KINASE)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		5 / 12 ILE A 943
VAL A 903
TRP A 906
LEU A 907
MET A 913
 None
 1.29A 2ziaB-3tadA:
undetectable		 2ziaB-3tadA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		4 / 8 LEU A1153
LEU A1138
TYR A1147
ILE A1156
 None
 0.94A 3cldB-3tadA:
undetectable		 3cldB-3tadA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 11 PHE C 829
ARG C 822
ALA C 809
LEU C 825
ALA C 826
 None
 1.47A 3pcqB-3tadC:
undetectable		 3pcqB-3tadC:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		3 / 3 LYS A1057
VAL A1061
HIS A1062
 None
 1.03A 3tj7A-3tadA:
undetectable		 3tj7A-3tadA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		4 / 8 SER A1109
SER A1031
ASN A1110
GLY A1077
 None
 1.00A 4af0A-3tadA:
undetectable		 4af0A-3tadA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		4 / 6 LEU A 909
TYR A1016
LEU A 885
GLU A 886
 None
 1.07A 4f3tA-3tadA:
undetectable		 4f3tA-3tadA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 11 ILE C 735
LEU C 687
ASP C 705
GLY C 706
PHE C 743
 None
 1.27A 4fogA-3tadC:
undetectable		 4fogA-3tadC:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 11 ILE C 735
LEU C 687
ASP C 705
GLY C 706
PHE C 743
 None
 1.33A 4fogC-3tadC:
undetectable		 4fogC-3tadC:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 726
HIS C 727
LEU C 692
GLY C 691
HIS C 793
 None
 1.50A 4lvcC-3tadC:
undetectable		 4lvcC-3tadC:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 GLY C 619
ALA C 616
GLY C 621
LEU C 624
LEU C 649
 None
 0.94A 4o33A-3tadC:
undetectable		 4o33A-3tadC:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		3 / 3 PRO A 914
MET A 913
TYR A 917
 None
 1.07A 4qa0B-3tadA:
undetectable		 4qa0B-3tadA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		3 / 3 PRO A 914
MET A 913
TYR A 917
 None
 1.11A 4qa0A-3tadA:
undetectable		 4qa0A-3tadA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		4 / 8 CYH A1080
SER A1137
LEU A1032
ILE A1078
 None
 0.93A 4xtaB-3tadA:
undetectable		 4xtaB-3tadA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		4 / 7 LEU A 909
TYR A1016
LEU A 885
GLU A 886
 None
 0.89A 4z4fA-3tadA:
undetectable		 4z4fA-3tadA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 726
HIS C 727
LEU C 692
GLY C 691
HIS C 793
 None
 1.48A 5hm8A-3tadC:
undetectable		 5hm8A-3tadC:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 726
HIS C 727
LEU C 692
GLY C 691
HIS C 793
 None
 1.48A 5hm8B-3tadC:
undetectable		 5hm8B-3tadC:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 726
HIS C 727
LEU C 692
GLY C 691
HIS C 793
 None
 1.48A 5hm8C-3tadC:
undetectable		 5hm8C-3tadC:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 726
HIS C 727
LEU C 692
GLY C 691
HIS C 793
 None
 1.48A 5hm8D-3tadC:
undetectable		 5hm8D-3tadC:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 726
HIS C 727
LEU C 692
GLY C 691
HIS C 793
 None
 1.48A 5hm8E-3tadC:
undetectable		 5hm8E-3tadC:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 726
HIS C 727
LEU C 692
GLY C 691
HIS C 793
 None
 1.48A 5hm8F-3tadC:
undetectable		 5hm8F-3tadC:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 726
HIS C 727
LEU C 692
GLY C 691
HIS C 793
 None
 1.48A 5hm8G-3tadC:
undetectable		 5hm8G-3tadC:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 726
HIS C 727
LEU C 692
GLY C 691
HIS C 793
 None
 1.48A 5hm8H-3tadC:
undetectable		 5hm8H-3tadC:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 ILE C 651
LEU C 660
SER C 626
GLY C 650
GLY C 627
 None
 1.24A 5nnaB-3tadC:
undetectable		 5nnaB-3tadC:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 ILE C 651
LEU C 660
SER C 626
GLY C 650
GLY C 627
 None
 1.22A 5nnaC-3tadC:
undetectable		 5nnaC-3tadC:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		4 / 7 LEU A 909
TYR A1016
LEU A 885
GLU A 886
 None
 0.85A 5t7bA-3tadA:
undetectable		 5t7bA-3tadA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		5 / 12 LEU C 726
HIS C 727
LEU C 692
GLY C 691
HIS C 793
 None
 1.48A 5utuH-3tadC:
undetectable		 5utuH-3tadC:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		3 / 3 MET A 913
ASP A1047
ARG A 955
 None
 1.07A 5z6jA-3tadA:
undetectable		 5z6jA-3tadA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3tad LIPRIN-ALPHA-2
(Homo
sapiens) 		3 / 3 MET A 913
ASP A1047
ARG A 955
 None
 1.15A 5z6kA-3tadA:
undetectable		 5z6kA-3tadA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 3tad LIPRIN-BETA-1
(Mus
musculus) 		4 / 5 ASN C 768
VAL C 683
LEU C 709
SER C 730
 None
 1.19A 6a7pA-3tadC:
undetectable		 6a7pA-3tadC:
17.80