SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tau'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 3tau GUANYLATE KINASE
(Listeria
monocytogenes) 		5 / 11 THR A  84
GLU A  91
LEU A  93
ILE A  99
ASP A  34
 None
 1.47A 1t6zA-3tauA:
undetectable		 1t6zA-3tauA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 3tau GUANYLATE KINASE
(Listeria
monocytogenes) 		5 / 11 ASP A 170
PRO A 125
GLY A  17
THR A  20
VAL A 172
 None
None
SO4  A 206 (-3.3A)
None
SO4  A 207 (-3.8A)
 1.39A 2uvnB-3tauA:
undetectable		 2uvnB-3tauA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G44_A_YTZA1512_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3tau GUANYLATE KINASE
(Listeria
monocytogenes) 		5 / 9 LEU A 128
VAL A 146
ARG A 149
MET A 150
ALA A 153
 None
 1.27A 5g44A-3tauA:
undetectable		 5g44A-3tauA:
19.86