SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3taw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 TYR A 306
GLY A 302
PHE A 270
 None
 0.70A 2m2pB-3tawA:
undetectable		 2m2pB-3tawA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 PHE A 353
ILE A 106
GLU A 235
SER A 208
ASP A 150
 UNL  A 388 ( 4.2A)
UNL  A 388 ( 4.8A)
UNL  A 387 ( 2.7A)
None
None
 1.44A 2pgfA-3tawA:
undetectable		 2pgfA-3tawA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 GLY A 268
ASP A 303
SER A 272
 None
EDO  A 400 (-3.5A)
None
 0.66A 2qhfA-3tawA:
undetectable		 2qhfA-3tawA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		4 / 6 SER A 118
VAL A 377
TYR A 367
ASP A 120
 None
 1.47A 2x45A-3tawA:
undetectable		 2x45A-3tawA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_1
(PHOSPHOLIPASE A2)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		5 / 10 GLU A 342
GLY A 369
PRO A  83
ARG A  49
LYS A 343
 None
 1.41A 3bjwD-3tawA:
undetectable		 3bjwD-3tawA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		4 / 5 PRO A 280
THR A 351
VAL A 352
GLY A 369
 EDO  A 394 (-3.9A)
UNL  A 388 ( 4.6A)
None
None
 1.18A 3elzA-3tawA:
undetectable		 3elzA-3tawA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 THR A 187
VAL A 177
THR A 179
VAL A 162
 None
 0.56A 3em0B-3tawA:
undetectable		 3em0B-3tawA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 ASP A 100
SER A 102
ARG A  69
 None
 0.83A 3loqA-3tawA:
undetectable		 3loqA-3tawA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 GLU A 194
GLU A 141
ASN A 142
 EDO  A 397 (-2.8A)
None
EDO  A 397 (-3.1A)
 0.81A 3lp9B-3tawA:
5.4
3lp9D-3tawA:
5.8		 3lp9B-3tawA:
20.78
3lp9D-3tawA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 GLU A 194
GLU A 143
ASN A 142
 EDO  A 397 (-2.8A)
None
EDO  A 397 (-3.1A)
 0.86A 3lp9B-3tawA:
5.4
3lp9D-3tawA:
5.8		 3lp9B-3tawA:
20.78
3lp9D-3tawA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 SER A 208
ARG A 152
GLY A 278
ALA A 371
GLY A 369
 None
 1.19A 4r29B-3tawA:
undetectable		 4r29B-3tawA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 LEU A 274
GLN A 273
LYS A 207
 None
None
UNL  A 387 (-2.7A)
 0.86A 6exiB-3tawA:
undetectable		 6exiB-3tawA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 LEU A 274
GLN A 273
LYS A 207
 None
None
UNL  A 387 (-2.7A)
 0.80A 6exiA-3tawA:
undetectable		 6exiA-3tawA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		4 / 8 LYS A  63
GLU A  76
ARG A 109
GLN A 104
 None
 1.07A 6fbvD-3tawA:
undetectable		 6fbvD-3tawA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		4 / 4 LEU A 113
ASP A 150
PRO A 151
ARG A  97
 None
 1.09A 6fgdA-3tawA:
undetectable		 6fgdA-3tawA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		4 / 6 GLY A 350
VAL A 354
PHE A 270
PHE A 334
 None
 1.00A 6h7lA-3tawA:
undetectable		 6h7lA-3tawA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE
(Parabacteroides
distasonis) 		4 / 6 GLY A 350
VAL A 354
PHE A 270
PHE A 334
 None
 1.01A 6h7lB-3tawA:
undetectable		 6h7lB-3tawA:
11.52