SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tb2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 10 PRO A  40
THR A  44
PRO A  45
CYH A  47
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-4.4A)
GOL  A 223 (-4.1A)
 0.54A 1h4oA-3tb2A:
17.6
1h4oB-3tb2A:
17.7		 1h4oA-3tb2A:
20.69
1h4oB-3tb2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 8 PRO A  40
THR A  44
PRO A  45
CYH A  47
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-4.4A)
GOL  A 223 (-4.1A)
 0.54A 1h4oB-3tb2A:
17.7		 1h4oB-3tb2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 9 PRO A  40
THR A  44
PRO A  45
CYH A  47
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-4.4A)
GOL  A 223 (-4.1A)
 0.57A 1h4oC-3tb2A:
17.5
1h4oD-3tb2A:
17.5		 1h4oC-3tb2A:
20.69
1h4oD-3tb2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 9 PRO A  40
THR A  44
PRO A  45
CYH A  47
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-4.4A)
GOL  A 223 (-4.1A)
 0.55A 1h4oD-3tb2A:
17.5		 1h4oD-3tb2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 9 PRO A  40
THR A  44
PRO A  45
CYH A  47
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-4.4A)
GOL  A 223 (-4.1A)
 0.53A 1h4oE-3tb2A:
17.6
1h4oF-3tb2A:
17.5		 1h4oE-3tb2A:
20.69
1h4oF-3tb2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 9 PRO A  40
THR A  44
PRO A  45
CYH A  47
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-4.4A)
GOL  A 223 (-4.1A)
 0.55A 1h4oF-3tb2A:
17.5		 1h4oF-3tb2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 8 PRO A  40
THR A  44
PRO A  45
CYH A  47
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-4.4A)
GOL  A 223 (-4.1A)
 0.56A 1h4oG-3tb2A:
17.6		 1h4oG-3tb2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 9 PRO A  40
THR A  44
PRO A  45
CYH A  47
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-4.4A)
GOL  A 223 (-4.1A)
 0.55A 1h4oH-3tb2A:
17.6		 1h4oH-3tb2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 9 PRO A  40
THR A  44
PRO A  45
CYH A  47
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-4.4A)
GOL  A 223 (-4.1A)
 0.58A 1hd2A-3tb2A:
17.5		 1hd2A-3tb2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 8 PRO A  40
THR A  44
PRO A  45
CYH A  47
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-4.4A)
GOL  A 223 (-4.1A)
 0.56A 1oc3A-3tb2A:
17.4		 1oc3A-3tb2A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 9 PRO A  40
THR A  44
PRO A  45
CYH A  47
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-4.4A)
GOL  A 223 (-4.1A)
 0.55A 1oc3B-3tb2A:
17.3		 1oc3B-3tb2A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		4 / 6 ARG A 152
ASP A  42
ASP A  80
GLU A  50
 None
 0.92A 1rjdA-3tb2A:
undetectable		 1rjdA-3tb2A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		4 / 6 ARG A 152
ASP A  42
ASP A  80
GLU A  50
 None
 0.91A 1rjdB-3tb2A:
undetectable		 1rjdB-3tb2A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		4 / 6 ARG A 152
ASP A  42
ASP A  80
GLU A  50
 None
 0.91A 1rjdC-3tb2A:
undetectable		 1rjdC-3tb2A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		4 / 7 ILE A  29
GLN A 165
LEU A 161
LEU A  68
 None
 0.98A 2qqcB-3tb2A:
undetectable
2qqcC-3tb2A:
undetectable		 2qqcB-3tb2A:
17.60
2qqcC-3tb2A:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		4 / 7 LEU A 161
LEU A  68
ILE A  29
GLN A 165
 None
 0.97A 2qqcA-3tb2A:
undetectable
2qqcF-3tb2A:
undetectable		 2qqcA-3tb2A:
13.74
2qqcF-3tb2A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		4 / 7 LEU A 161
LEU A  68
ILE A  29
GLN A 165
 None
 1.05A 2qqcG-3tb2A:
undetectable
2qqcJ-3tb2A:
undetectable		 2qqcG-3tb2A:
13.74
2qqcJ-3tb2A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		4 / 7 LEU A 161
LEU A  68
ILE A  29
GLN A 165
 None
 0.95A 2qqcI-3tb2A:
undetectable
2qqcL-3tb2A:
undetectable		 2qqcI-3tb2A:
13.74
2qqcL-3tb2A:
17.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 7 THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
 GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
 0.53A 2v2gA-3tb2A:
30.1
2v2gB-3tb2A:
30.3		 2v2gA-3tb2A:
45.34
2v2gB-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 7 THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
 GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
 0.53A 2v2gA-3tb2A:
30.1
2v2gB-3tb2A:
30.3		 2v2gA-3tb2A:
45.34
2v2gB-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 7 THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
 GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
 0.57A 2v2gC-3tb2A:
30.2
2v2gD-3tb2A:
30.4		 2v2gC-3tb2A:
45.34
2v2gD-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 7 THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
 GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
 0.55A 2v2gC-3tb2A:
30.2
2v2gD-3tb2A:
30.4		 2v2gC-3tb2A:
45.34
2v2gD-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		6 / 8 THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
ALA A 148
 GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
GOL  A 223 (-3.6A)
 0.53A 2v32A-3tb2A:
30.0
2v32B-3tb2A:
30.3		 2v32A-3tb2A:
45.34
2v32B-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		6 / 8 THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
ALA A 148
 GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
GOL  A 223 (-3.6A)
 0.49A 2v32A-3tb2A:
30.0
2v32B-3tb2A:
30.3		 2v32A-3tb2A:
45.34
2v32B-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		6 / 8 PRO A  40
THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
 0.60A 2v32C-3tb2A:
30.0
2v32D-3tb2A:
30.2		 2v32C-3tb2A:
45.34
2v32D-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 8 THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
 GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
 0.50A 2v32C-3tb2A:
30.0
2v32D-3tb2A:
30.2		 2v32C-3tb2A:
45.34
2v32D-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_A_BEZA1222_0
(PEROXIREDOXIN 6.)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		7 / 9 PRO A  40
THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
ALA A 148
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
GOL  A 223 (-3.6A)
 0.58A 2v41A-3tb2A:
30.1
2v41B-3tb2A:
30.0		 2v41A-3tb2A:
45.34
2v41B-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_B_BEZB1222_0
(PEROXIREDOXIN 6.)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		7 / 9 PRO A  40
THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
ALA A 148
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
GOL  A 223 (-3.6A)
 0.54A 2v41A-3tb2A:
30.1
2v41B-3tb2A:
30.0		 2v41A-3tb2A:
45.34
2v41B-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		6 / 8 PRO A  40
THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
 0.61A 2v41C-3tb2A:
30.2
2v41D-3tb2A:
30.1		 2v41C-3tb2A:
45.34
2v41D-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		6 / 8 PRO A  40
THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
 0.63A 2v41C-3tb2A:
30.2
2v41D-3tb2A:
30.1		 2v41C-3tb2A:
45.34
2v41D-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 7 THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
 GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
 0.56A 2v41E-3tb2A:
30.1
2v41F-3tb2A:
30.0		 2v41E-3tb2A:
45.34
2v41F-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 7 THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
 GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
 0.67A 2v41E-3tb2A:
30.1
2v41F-3tb2A:
30.0		 2v41E-3tb2A:
45.34
2v41F-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 8 THR A  44
PRO A  45
VAL A  46
ARG A 129
ALA A 148
 GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-4.1A)
GOL  A 223 (-3.6A)
 0.29A 2v41G-3tb2A:
29.7
2v41H-3tb2A:
30.2		 2v41G-3tb2A:
45.34
2v41H-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		4 / 8 VAL A  46
GLU A 118
ARG A 129
ALA A 148
 GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
GOL  A 223 (-3.6A)
 0.52A 2v41G-3tb2A:
29.7
2v41H-3tb2A:
30.2		 2v41G-3tb2A:
45.34
2v41H-3tb2A:
45.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		6 / 8 PRO A  40
THR A  44
PRO A  45
VAL A  46
GLU A 118
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-3.7A)
GOL  A 223 (-3.4A)
GOL  A 223 (-4.1A)
 0.63A 2v41G-3tb2A:
29.7
2v41H-3tb2A:
30.2		 2v41G-3tb2A:
45.34
2v41H-3tb2A:
45.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 10 PRO A  40
THR A  44
PRO A  45
CYH A  47
ARG A 129
 GOL  A 223 (-4.3A)
GOL  A 223 ( 4.3A)
GOL  A 223 (-3.6A)
GOL  A 223 (-4.4A)
GOL  A 223 (-4.1A)
 0.56A 2vl2A-3tb2A:
17.4
2vl2C-3tb2A:
15.5		 2vl2A-3tb2A:
20.42
2vl2C-3tb2A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		4 / 8 ARG A 152
ASP A  42
ASP A  80
GLU A  50
 None
 0.82A 2zw9A-3tb2A:
undetectable		 2zw9A-3tb2A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NNR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 12 PHE A  12
VAL A 100
ARG A 152
ILE A  35
PRO A  40
 None
None
None
None
GOL  A 223 (-4.3A)
 1.23A 4nnrA-3tb2A:
undetectable
4nnrB-3tb2A:
undetectable		 4nnrA-3tb2A:
21.82
4nnrB-3tb2A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		5 / 12 HIS A  79
LEU A 126
HIS A  39
ASP A  42
SER A  78
 None
 1.44A 4r88A-3tb2A:
undetectable		 4r88A-3tb2A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		4 / 6 HIS A  79
ASP A  42
HIS A  39
TRP A  95
 None
 1.33A 5m45A-3tb2A:
undetectable		 5m45A-3tb2A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		4 / 6 HIS A  79
ASP A  42
HIS A  39
TRP A  95
 None
 1.33A 5m45D-3tb2A:
undetectable		 5m45D-3tb2A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		4 / 6 HIS A  79
ASP A  42
HIS A  39
TRP A  95
 None
 1.33A 5m45G-3tb2A:
undetectable		 5m45G-3tb2A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 3tb2 1-CYS PEROXIREDOXIN
(Plasmodium
yoelii) 		4 / 6 HIS A  79
ASP A  42
HIS A  39
TRP A  95
 None
 1.33A 5m45J-3tb2A:
undetectable		 5m45J-3tb2A:
13.77