SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tb6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 3tb6 ARABINOSE METABOLISM
TRANSCRIPTIONAL
REPRESSOR
(Bacillus
subtilis) 		3 / 3 ASP A 302
ASP A 274
LYS A 320
 None
 1.06A 1lqtB-3tb6A:
2.9		 1lqtB-3tb6A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 3tb6 ARABINOSE METABOLISM
TRANSCRIPTIONAL
REPRESSOR
(Bacillus
subtilis) 		3 / 3 ASP A 302
ASP A 274
LYS A 320
 None
 1.09A 1lquB-3tb6A:
2.9		 1lquB-3tb6A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3tb6 ARABINOSE METABOLISM
TRANSCRIPTIONAL
REPRESSOR
(Bacillus
subtilis) 		5 / 12 ILE A 297
VAL A 280
LEU A 284
LEU A 258
THR A 257
 None
 1.00A 2aw1A-3tb6A:
undetectable		 2aw1A-3tb6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 3tb6 ARABINOSE METABOLISM
TRANSCRIPTIONAL
REPRESSOR
(Bacillus
subtilis) 		3 / 3 THR A 144
LYS A 279
GLU A 142
 None
None
ARB  A 400 (-4.4A)
 0.81A 3ijdB-3tb6A:
undetectable		 3ijdB-3tb6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 3tb6 ARABINOSE METABOLISM
TRANSCRIPTIONAL
REPRESSOR
(Bacillus
subtilis) 		4 / 8 ILE A  82
ILE A 136
VAL A 331
ILE A 164
 None
 0.83A 3p4wC-3tb6A:
undetectable		 3p4wC-3tb6A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3tb6 ARABINOSE METABOLISM
TRANSCRIPTIONAL
REPRESSOR
(Bacillus
subtilis) 		4 / 5 LEU A 132
LEU A 139
GLY A 138
GLY A  83
 None
 0.84A 3si7C-3tb6A:
undetectable
3si7D-3tb6A:
1.3		 3si7C-3tb6A:
22.87
3si7D-3tb6A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3tb6 ARABINOSE METABOLISM
TRANSCRIPTIONAL
REPRESSOR
(Bacillus
subtilis) 		3 / 3 THR A  87
ASN A 119
GLU A 142
 None
None
ARB  A 400 (-4.4A)
 0.74A 3v4tA-3tb6A:
undetectable
3v4tC-3tb6A:
undetectable		 3v4tA-3tb6A:
21.14
3v4tC-3tb6A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 3tb6 ARABINOSE METABOLISM
TRANSCRIPTIONAL
REPRESSOR
(Bacillus
subtilis) 		5 / 9 LEU A  85
ILE A 101
LEU A 105
ILE A 169
GLY A 138
 None
 1.11A 4kukA-3tb6A:
undetectable		 4kukA-3tb6A:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3tb6 ARABINOSE METABOLISM
TRANSCRIPTIONAL
REPRESSOR
(Bacillus
subtilis) 		5 / 12 ALA A 328
GLY A 138
GLY A  83
LEU A 132
LEU A 131
 None
 1.01A 4lg1A-3tb6A:
undetectable		 4lg1A-3tb6A:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3tb6 ARABINOSE METABOLISM
TRANSCRIPTIONAL
REPRESSOR
(Bacillus
subtilis) 		5 / 12 ALA A 328
GLY A 138
GLY A  83
LEU A 132
LEU A 131
 None
 0.99A 4lg1B-3tb6A:
undetectable		 4lg1B-3tb6A:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3tb6 ARABINOSE METABOLISM
TRANSCRIPTIONAL
REPRESSOR
(Bacillus
subtilis) 		5 / 12 ALA A 328
GLY A 138
GLY A  83
LEU A 132
LEU A 131
 None
 1.00A 4lg1C-3tb6A:
undetectable		 4lg1C-3tb6A:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 3tb6 ARABINOSE METABOLISM
TRANSCRIPTIONAL
REPRESSOR
(Bacillus
subtilis) 		5 / 12 LEU A 128
LEU A 139
ALA A 178
MET A 168
LEU A 157
 None
 1.10A 5og9B-3tb6A:
undetectable		 5og9B-3tb6A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 3tb6 ARABINOSE METABOLISM
TRANSCRIPTIONAL
REPRESSOR
(Bacillus
subtilis) 		4 / 5 GLY A 299
LEU A 313
SER A 303
TYR A  92
 None
None
None
ARB  A 400 (-4.7A)
 1.28A 6ji6A-3tb6A:
undetectable		 6ji6A-3tb6A:
23.00