SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tbj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 3tbj ACTIBIND
(Aspergillus
niger) 		4 / 7 TYR A 237
VAL A 228
ILE A 145
GLY A 230
 None
 0.87A 11gsA-3tbjA:
undetectable		 11gsA-3tbjA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3tbj ACTIBIND
(Aspergillus
niger) 		4 / 8 TYR A 237
VAL A 228
ILE A 145
GLY A 230
 None
 0.88A 2gssA-3tbjA:
undetectable		 2gssA-3tbjA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3tbj ACTIBIND
(Aspergillus
niger) 		4 / 8 TYR A 237
VAL A 228
ILE A 145
GLY A 230
 None
 0.88A 2gssB-3tbjA:
undetectable		 2gssB-3tbjA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 3tbj ACTIBIND
(Aspergillus
niger) 		4 / 8 TYR A 121
ASP A 120
TRP A 118
HIS A 138
 EDO  A 307 ( 3.7A)
None
None
PO4  A 304 (-3.9A)
 1.37A 2ha2A-3tbjA:
undetectable		 2ha2A-3tbjA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3tbj ACTIBIND
(Aspergillus
niger) 		4 / 7 TYR A 237
VAL A 228
ILE A 145
GLY A 230
 None
 0.89A 3gssA-3tbjA:
undetectable		 3gssA-3tbjA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3tbj ACTIBIND
(Aspergillus
niger) 		4 / 7 TYR A 237
VAL A 228
ILE A 145
GLY A 230
 None
 0.89A 3gssB-3tbjA:
undetectable		 3gssB-3tbjA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3tbj ACTIBIND
(Aspergillus
niger) 		4 / 8 TYR A 237
VAL A 228
ILE A 145
GLY A 230
 None
 0.85A 3hjoA-3tbjA:
undetectable		 3hjoA-3tbjA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3tbj ACTIBIND
(Aspergillus
niger) 		5 / 12 GLU A 158
PRO A 147
GLY A 160
ILE A  98
ASN A  97
 None
None
None
None
NAG  A 301 (-1.8A)
 1.28A 3jb2A-3tbjA:
undetectable		 3jb2A-3tbjA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 3tbj ACTIBIND
(Aspergillus
niger) 		3 / 3 HIS A  74
PHE A 163
PHE A 162
 PO4  A 304 (-3.9A)
None
None
 0.58A 3lk0D-3tbjA:
0.3		 3lk0D-3tbjA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 3tbj ACTIBIND
(Aspergillus
niger) 		4 / 8 TYR A 237
VAL A 228
ILE A 145
GLY A 230
 None
 0.83A 3n9jA-3tbjA:
undetectable		 3n9jA-3tbjA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 3tbj ACTIBIND
(Aspergillus
niger) 		5 / 9 THR A  99
GLN A 105
LEU A 111
LEU A 110
ARG A 107
 None
None
None
PO4  A 305 (-4.2A)
None
 1.49A 3nbqD-3tbjA:
undetectable		 3nbqD-3tbjA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 3tbj ACTIBIND
(Aspergillus
niger) 		5 / 10 ILE A 142
TYR A 150
ILE A 145
GLU A 158
ARG A  93
 None
 1.26A 3u6tA-3tbjA:
undetectable		 3u6tA-3tbjA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3tbj ACTIBIND
(Aspergillus
niger) 		4 / 7 TYR A 223
TYR A 121
PRO A 256
TYR A  61
 None
EDO  A 307 ( 3.7A)
None
None
 1.31A 3ugrA-3tbjA:
undetectable		 3ugrA-3tbjA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X30_A_T44A401_1
(THYROXINE-BINDING
GLOBULIN)		 3tbj ACTIBIND
(Aspergillus
niger) 		5 / 9 ALA A 232
GLN A  57
LEU A 173
LEU A  76
LEU A 169
 None
 1.49A 4x30A-3tbjA:
undetectable		 4x30A-3tbjA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 3tbj ACTIBIND
(Aspergillus
niger) 		4 / 5 LEU A 169
TYR A 237
ALA A 232
ILE A 233
 None
 1.19A 4y03B-3tbjA:
undetectable		 4y03B-3tbjA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 3tbj ACTIBIND
(Aspergillus
niger) 		4 / 8 PRO A  67
TYR A 117
SER A 180
SER A  64
 None
 1.11A 5l1fA-3tbjA:
undetectable
5l1fB-3tbjA:
undetectable		 5l1fA-3tbjA:
16.32
5l1fB-3tbjA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 3tbj ACTIBIND
(Aspergillus
niger) 		3 / 3 LYS A 137
HIS A 133
HIS A 138
 PO4  A 304 (-2.9A)
PO4  A 304 (-3.7A)
PO4  A 304 (-3.9A)
 1.29A 5oexA-3tbjA:
undetectable		 5oexA-3tbjA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 3tbj ACTIBIND
(Aspergillus
niger) 		3 / 3 LYS A 137
HIS A 133
HIS A 138
 PO4  A 304 (-2.9A)
PO4  A 304 (-3.7A)
PO4  A 304 (-3.9A)
 1.29A 5oexB-3tbjA:
undetectable		 5oexB-3tbjA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 3tbj ACTIBIND
(Aspergillus
niger) 		3 / 3 LYS A 137
HIS A 133
HIS A 138
 PO4  A 304 (-2.9A)
PO4  A 304 (-3.7A)
PO4  A 304 (-3.9A)
 1.30A 5oexC-3tbjA:
undetectable		 5oexC-3tbjA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 3tbj ACTIBIND
(Aspergillus
niger) 		3 / 3 LYS A 137
HIS A 133
HIS A 138
 PO4  A 304 (-2.9A)
PO4  A 304 (-3.7A)
PO4  A 304 (-3.9A)
 1.30A 5oexD-3tbjA:
undetectable		 5oexD-3tbjA:
16.04