SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tc1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 7 GLN A   5
PHE A 166
MET A  43
ALA A  45
 None
 1.26A 1linA-3tc1A:
undetectable		 1linA-3tc1A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		3 / 3 PHE A 196
LEU A  38
MET A  43
 None
 0.77A 1mx1D-3tc1A:
undetectable		 1mx1D-3tc1A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 12 ARG A  39
LEU A  46
LEU A 295
LEU A  38
LEU A   6
 None
 1.20A 1og5A-3tc1A:
undetectable		 1og5A-3tc1A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 8 ASP A 200
TYR A 155
LEU A 159
THR A 272
 MG  A 500 (-2.9A)
None
None
None
 0.96A 1rmtD-3tc1A:
undetectable		 1rmtD-3tc1A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		6 / 11 SER A  73
LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.79A 1rqjA-3tc1A:
25.8		 1rqjA-3tc1A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		6 / 11 SER A  73
LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
None
MG  A 500 (-2.9A)
 0.64A 1rqjA-3tc1A:
25.8		 1rqjA-3tc1A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		6 / 11 SER A  73
LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.74A 1rqjB-3tc1A:
25.7		 1rqjB-3tc1A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		6 / 11 SER A  73
LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
None
MG  A 500 (-2.9A)
 0.60A 1rqjB-3tc1A:
25.7		 1rqjB-3tc1A:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 11 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.73A 1yhlA-3tc1A:
25.1		 1yhlA-3tc1A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 11 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.47A 1yhlA-3tc1A:
25.1		 1yhlA-3tc1A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 11 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.81A 1yq7A-3tc1A:
25.9		 1yq7A-3tc1A:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 11 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.53A 1yq7A-3tc1A:
25.9		 1yq7A-3tc1A:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.70A 1yv5A-3tc1A:
26.0		 1yv5A-3tc1A:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.49A 1yv5A-3tc1A:
26.0		 1yv5A-3tc1A:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 9 ASP A  77
LYS A 162
THR A 163
GLN A 197
LYS A 224
 None
 0.94A 2e91A-3tc1A:
13.0		 2e91A-3tc1A:
26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 9 ASP A  77
LYS A 162
THR A 163
GLN A 197
LYS A 224
 None
 0.97A 2e91B-3tc1A:
20.5		 2e91B-3tc1A:
26.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 11 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.69A 2f8cF-3tc1A:
26.2		 2f8cF-3tc1A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 11 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.45A 2f8cF-3tc1A:
26.2		 2f8cF-3tc1A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.68A 2f8zF-3tc1A:
26.1		 2f8zF-3tc1A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.47A 2f8zF-3tc1A:
26.1		 2f8zF-3tc1A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 12 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.73A 2f94F-3tc1A:
25.9		 2f94F-3tc1A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 12 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.51A 2f94F-3tc1A:
25.9		 2f94F-3tc1A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.75A 2f9kF-3tc1A:
26.0		 2f9kF-3tc1A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.47A 2f9kF-3tc1A:
26.0		 2f9kF-3tc1A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 9 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.95A 2o1oA-3tc1A:
23.3		 2o1oA-3tc1A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		6 / 10 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
LYS A 224
 None
 0.89A 2o1oB-3tc1A:
24.4		 2o1oB-3tc1A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 ASP A  77
LYS A 162
THR A 163
GLN A 197
ASP A 201
 None
 0.94A 2q58A-3tc1A:
23.5		 2q58A-3tc1A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 201
 None
 0.68A 2q58A-3tc1A:
23.5		 2q58A-3tc1A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 9 ASP A  77
LYS A 162
THR A 163
GLN A 197
LYS A 224
 None
 0.87A 2q58B-3tc1A:
24.3		 2q58B-3tc1A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 12 LEU A 231
THR A 272
LYS A 224
GLN A 197
ASP A 219
 None
None
None
None
MG  A 500 ( 4.0A)
 1.41A 2vavB-3tc1A:
0.0		 2vavB-3tc1A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_I_CSCI1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 12 LEU A 231
THR A 272
LYS A 224
GLN A 197
ASP A 219
 None
None
None
None
MG  A 500 ( 4.0A)
 1.40A 2vavI-3tc1A:
0.0		 2vavI-3tc1A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		3 / 3 ASN A 216
ASP A 201
GLN A 197
 None
 0.79A 3eeyC-3tc1A:
undetectable		 3eeyC-3tc1A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		3 / 3 ASN A 216
ASP A 201
GLN A 197
 None
 0.80A 3eeyD-3tc1A:
undetectable		 3eeyD-3tc1A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		3 / 3 ASN A 216
ASP A 201
GLN A 197
 None
 0.77A 3eeyE-3tc1A:
undetectable		 3eeyE-3tc1A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.79A 3ez3D-3tc1A:
25.2		 3ez3D-3tc1A:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.43A 3ez3D-3tc1A:
25.2		 3ez3D-3tc1A:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_D_TOPD200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 9 ALA A 276
VAL A 302
ILE A 167
LEU A  38
PHE A 192
 None
 1.38A 3fl9D-3tc1A:
undetectable		 3fl9D-3tc1A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 11 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.75A 3n45F-3tc1A:
26.1		 3n45F-3tc1A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 11 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.47A 3n45F-3tc1A:
26.1		 3n45F-3tc1A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.73A 3n46F-3tc1A:
26.0		 3n46F-3tc1A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.46A 3n46F-3tc1A:
26.0		 3n46F-3tc1A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 6 GLU A 296
ILE A 287
GLU A 290
ASN A 291
 None
 1.03A 3pgyA-3tc1A:
undetectable
3pgyB-3tc1A:
undetectable		 3pgyA-3tc1A:
23.50
3pgyB-3tc1A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		3 / 3 PHE A 166
SER A  73
GLN A  70
 None
 0.88A 3smtA-3tc1A:
0.1		 3smtA-3tc1A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 8 ASP A 201
GLU A 138
ASP A 219
GLU A 222
 None
None
MG  A 500 ( 4.0A)
None
 1.14A 4feuF-3tc1A:
undetectable		 4feuF-3tc1A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 7 ASP A 201
GLU A 138
ASP A 219
GLU A 222
 None
None
MG  A 500 ( 4.0A)
None
 1.15A 4fexB-3tc1A:
undetectable		 4fexB-3tc1A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.72A 4kpdA-3tc1A:
26.2		 4kpdA-3tc1A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.49A 4kpdA-3tc1A:
26.2		 4kpdA-3tc1A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 9 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.77A 4kpjA-3tc1A:
26.0		 4kpjA-3tc1A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 9 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.51A 4kpjA-3tc1A:
26.0		 4kpjA-3tc1A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.76A 4kq5A-3tc1A:
25.9		 4kq5A-3tc1A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.53A 4kq5A-3tc1A:
25.9		 4kq5A-3tc1A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.74A 4kqsA-3tc1A:
26.3		 4kqsA-3tc1A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.49A 4kqsA-3tc1A:
26.3		 4kqsA-3tc1A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.74A 4nkeA-3tc1A:
26.0		 4nkeA-3tc1A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.48A 4nkeA-3tc1A:
26.0		 4nkeA-3tc1A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 9 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.78A 4nkfA-3tc1A:
26.0		 4nkfA-3tc1A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 9 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.52A 4nkfA-3tc1A:
26.0		 4nkfA-3tc1A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.74A 4nuaA-3tc1A:
26.1		 4nuaA-3tc1A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.48A 4nuaA-3tc1A:
26.1		 4nuaA-3tc1A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 9 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.72A 4oguA-3tc1A:
25.7		 4oguA-3tc1A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 9 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.43A 4oguA-3tc1A:
25.7		 4oguA-3tc1A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 11 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.72A 4p0wA-3tc1A:
26.2		 4p0wA-3tc1A:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 11 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.49A 4p0wA-3tc1A:
26.2		 4p0wA-3tc1A:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.75A 4rxdA-3tc1A:
24.7		 4rxdA-3tc1A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.45A 4rxdA-3tc1A:
24.7		 4rxdA-3tc1A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.72A 4rxdB-3tc1A:
24.8		 4rxdB-3tc1A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.46A 4rxdB-3tc1A:
24.8		 4rxdB-3tc1A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.74A 4rxdC-3tc1A:
24.9		 4rxdC-3tc1A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 10 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.46A 4rxdC-3tc1A:
24.9		 4rxdC-3tc1A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 12 TYR A 155
TRP A 156
THR A 272
THR A 275
ALA A 276
 None
 0.79A 4u15A-3tc1A:
undetectable		 4u15A-3tc1A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 8 SER A  73
LEU A  74
ASP A  77
LYS A 162
 None
 0.90A 4umjA-3tc1A:
22.8		 4umjA-3tc1A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 9 SER A  73
LEU A  74
ASP A  77
LYS A 162
THR A 163
 None
 0.79A 4umjB-3tc1A:
22.9		 4umjB-3tc1A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 7 ILE A 167
LYS A 172
LEU A 171
GLY A 189
 None
 0.74A 5a06A-3tc1A:
undetectable		 5a06A-3tc1A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 7 ILE A 167
LYS A 172
LEU A 171
GLY A 189
 None
 0.74A 5a06B-3tc1A:
undetectable		 5a06B-3tc1A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 7 ILE A 167
LYS A 172
LEU A 171
GLY A 189
 None
 0.75A 5a06C-3tc1A:
undetectable		 5a06C-3tc1A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 7 ILE A 167
LYS A 172
LEU A 171
GLY A 189
 None
 0.75A 5a06E-3tc1A:
undetectable		 5a06E-3tc1A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 7 ILE A 167
LYS A 172
LEU A 171
GLY A 189
 None
 0.75A 5a06F-3tc1A:
undetectable		 5a06F-3tc1A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 5 GLU A 271
THR A 272
THR A 225
LEU A 244
 None
 1.29A 5axaA-3tc1A:
undetectable		 5axaA-3tc1A:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 5 GLU A 271
THR A 272
THR A 225
LEU A 244
 None
 1.29A 5axaC-3tc1A:
undetectable		 5axaC-3tc1A:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 12 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.74A 5cg5A-3tc1A:
25.4		 5cg5A-3tc1A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 12 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.47A 5cg5A-3tc1A:
25.4		 5cg5A-3tc1A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 12 LEU A  74
ASP A  77
LYS A 162
THR A 163
GLN A 197
 None
 0.75A 5cg6A-3tc1A:
25.7		 5cg6A-3tc1A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 12 LEU A  74
LYS A 162
THR A 163
GLN A 197
ASP A 200
 None
None
None
None
MG  A 500 (-2.9A)
 0.49A 5cg6A-3tc1A:
25.7		 5cg6A-3tc1A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 12 LEU A  42
LEU A  56
LEU A   6
ILE A   9
ALA A   8
 None
 1.30A 5j7wC-3tc1A:
undetectable		 5j7wC-3tc1A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 4 GLU A 271
THR A 272
THR A 225
LEU A 244
 None
 1.32A 5v96C-3tc1A:
undetectable		 5v96C-3tc1A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		4 / 4 GLU A 271
THR A 272
THR A 225
LEU A 244
 None
 1.32A 5v96D-3tc1A:
undetectable		 5v96D-3tc1A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)		 3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE
(Helicobacter
pylori) 		5 / 12 LEU A  42
LEU A  56
LEU A   6
ILE A   9
ALA A   8
 None
 1.42A 6qyaB-3tc1A:
undetectable		 6qyaB-3tc1A:
24.05