SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 183
GLY A 165
GLY A 164
VAL A 182
GLY A 204
 None
None
PO4  A 481 (-4.8A)
None
None
 0.88A 1n2xB-3tc9A:
undetectable		 1n2xB-3tc9A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 189
ASP A 154
THR A 142
GLY A 141
 EDO  A 492 (-3.5A)
EDO  A 492 ( 4.0A)
None
None
 1.01A 2f6dA-3tc9A:
undetectable		 2f6dA-3tc9A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A 173
ASP A 172
SER A 241
PHE A 243
 None
 1.20A 2p02A-3tc9A:
undetectable		 2p02A-3tc9A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 LEU A 333
ILE A 302
ILE A 222
LEU A 249
 None
 0.76A 2xkwB-3tc9A:
undetectable		 2xkwB-3tc9A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PHE A 440
GLY A 454
ILE A 393
PHE A 425
 EDO  A 490 (-4.9A)
None
None
None
 0.97A 3ko0O-3tc9A:
undetectable
3ko0Q-3tc9A:
undetectable		 3ko0O-3tc9A:
11.74
3ko0Q-3tc9A:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T8N_D_EDTD135_0
(STEROID
DELTA-ISOMERASE)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 11 GLY A 155
PRO A 156
GLY A 162
ARG A 189
ASP A 158
 None
None
None
EDO  A 492 (-3.5A)
None
 1.36A 3t8nD-3tc9A:
undetectable
3t8nF-3tc9A:
undetectable		 3t8nD-3tc9A:
15.68
3t8nF-3tc9A:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 PRO A 187
THR A 188
LEU A 205
 EDO  A 492 ( 4.7A)
None
EDO  A 496 ( 4.7A)
 0.80A 3ttrA-3tc9A:
undetectable		 3ttrA-3tc9A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 235
ILE A 236
ASN A 233
ILE A 221
 None
 1.06A 4jtpA-3tc9A:
undetectable		 4jtpA-3tc9A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A 173
ASP A 172
SER A 241
PHE A 243
 None
 1.18A 4kttA-3tc9A:
undetectable		 4kttA-3tc9A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A 173
ASP A 172
SER A 241
PHE A 243
 None
 1.22A 4kttC-3tc9A:
undetectable		 4kttC-3tc9A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A 173
ASP A 172
SER A 241
PHE A 243
 None
 1.16A 4ndnA-3tc9A:
undetectable		 4ndnA-3tc9A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PRO A 173
ASP A 172
SER A 241
PHE A 243
 None
 1.22A 4ndnC-3tc9A:
undetectable		 4ndnC-3tc9A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PRO A 173
ASP A 172
SER A 241
PHE A 243
 None
 1.25A 4odjA-3tc9A:
undetectable		 4odjA-3tc9A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 344
ALA A 345
ALA A 356
VAL A 400
GLN A 342
 None
 1.48A 4ryaA-3tc9A:
undetectable		 4ryaA-3tc9A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A 173
ASP A 172
SER A 241
PHE A 243
 None
 1.16A 5a1iA-3tc9A:
undetectable		 5a1iA-3tc9A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PRO A 173
ASP A 172
SER A 241
PHE A 243
 None
 1.16A 5a1iA-3tc9A:
undetectable		 5a1iA-3tc9A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 4 LEU A 181
ARG A 448
ILE A 450
PHE A 163
 None
PO4  A 481 (-2.9A)
None
None
 1.34A 5kirB-3tc9A:
undetectable		 5kirB-3tc9A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 TYR A 180
ASP A 192
ASP A 172
 None
 0.86A 5x6yA-3tc9A:
undetectable		 5x6yA-3tc9A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 386
ASN A 426
GLU A 446
ARG A 445
 None
None
PO4  A 481 ( 4.5A)
PO4  A 481 (-4.1A)
 1.12A 6b94A-3tc9A:
undetectable		 6b94A-3tc9A:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A 173
ASP A 172
SER A 241
PHE A 243
 None
 1.19A 6fboA-3tc9A:
undetectable		 6fboA-3tc9A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A 173
ASP A 172
SER A 241
PHE A 243
 None
 1.18A 6fcdA-3tc9A:
undetectable		 6fcdA-3tc9A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3tc9 HYPOTHETICAL
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PRO A 173
ASP A 172
SER A 241
PHE A 243
 None
 1.16A 6g6rA-3tc9A:
undetectable		 6g6rA-3tc9A:
23.41