SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tca'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 3tca AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING
FAMILY B MEMBER
1-INTERACTING
PROTEIN
(Mus
musculus) 		5 / 12 TYR A 422
LEU A 337
LEU A 316
LEU A 387
ILE A 342
 None
 1.34A 1fmlA-3tcaA:
undetectable		 1fmlA-3tcaA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 3tca AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING
FAMILY B MEMBER
1-INTERACTING
PROTEIN
(Mus
musculus) 		4 / 6 ILE A 371
LYS A 376
LYS A 374
ALA A 379
 None
 1.21A 1hk2A-3tcaA:
undetectable		 1hk2A-3tcaA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 3tca AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING
FAMILY B MEMBER
1-INTERACTING
PROTEIN
(Mus
musculus) 		3 / 3 ASP A 428
GLU A 299
TYR A 277
 None
 0.79A 1wsvA-3tcaA:
undetectable		 1wsvA-3tcaA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3tca AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING
FAMILY B MEMBER
1-INTERACTING
PROTEIN
(Mus
musculus) 		5 / 12 ILE A 233
GLY A 370
ALA A 379
VAL A 386
ILE A 399
 None
 0.94A 4rvdA-3tcaA:
undetectable		 4rvdA-3tcaA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 3tca AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING
FAMILY B MEMBER
1-INTERACTING
PROTEIN
(Mus
musculus) 		5 / 12 ILE A 233
GLY A 370
ALA A 379
VAL A 386
ILE A 399
 None
 0.94A 4rvgA-3tcaA:
undetectable		 4rvgA-3tcaA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 3tca AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING
FAMILY B MEMBER
1-INTERACTING
PROTEIN
(Mus
musculus) 		4 / 8 LEU A 426
TYR A 422
GLU A 241
ASN A 366
 None
 1.08A 6c71B-3tcaA:
undetectable		 6c71B-3tcaA:
11.34