SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tcr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3tcr MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
(Mycobacteroides
abscessus) 		5 / 12 ARG A 119
LEU A 162
GLY A 131
GLY A 122
ILE A 148
 None
 1.11A 1p91B-3tcrA:
undetectable		 1p91B-3tcrA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 3tcr MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
(Mycobacteroides
abscessus) 		4 / 7 ALA A  77
GLY A 141
ILE A 139
THR A 103
 None
 0.80A 1t7iB-3tcrA:
undetectable		 1t7iB-3tcrA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 3tcr MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
(Mycobacteroides
abscessus) 		4 / 7 ALA A  77
GLY A 141
ILE A 139
THR A 103
 None
 0.84A 1t7jB-3tcrA:
undetectable		 1t7jB-3tcrA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 3tcr MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
(Mycobacteroides
abscessus) 		5 / 12 LEU A 162
LEU A  50
ILE A  29
GLY A  43
LEU A  45
 None
 1.23A 2j7xA-3tcrA:
undetectable		 2j7xA-3tcrA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 3tcr MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
(Mycobacteroides
abscessus) 		5 / 12 MET A 159
THR A 163
ALA A 166
LEU A 144
LEU A  50
 None
 1.12A 2qxsB-3tcrA:
undetectable		 2qxsB-3tcrA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 3tcr MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
(Mycobacteroides
abscessus) 		4 / 7 THR A  87
LEU A 106
VAL A  63
VAL A  30
 None
 0.95A 4cp4A-3tcrA:
undetectable		 4cp4A-3tcrA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3tcr MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
(Mycobacteroides
abscessus) 		5 / 12 LEU A 162
LEU A  50
ILE A  29
GLY A  43
LEU A  45
 None
 1.21A 4j26A-3tcrA:
undetectable		 4j26A-3tcrA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3tcr MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
(Mycobacteroides
abscessus) 		5 / 12 ALA A 149
GLY A 150
GLY A  89
ASN A 147
GLY A 158
 None
 1.08A 4obwB-3tcrA:
undetectable		 4obwB-3tcrA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 3tcr MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
(Mycobacteroides
abscessus) 		5 / 11 LEU A 162
LEU A  50
ILE A  29
GLY A  43
LEU A  45
 None
 1.24A 4pxmB-3tcrA:
undetectable		 4pxmB-3tcrA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 3tcr MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
(Mycobacteroides
abscessus) 		5 / 12 GLY A 150
ILE A 114
ALA A 137
GLY A 135
GLU A 101
 None
 1.11A 4r29D-3tcrA:
undetectable		 4r29D-3tcrA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3tcr MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
(Mycobacteroides
abscessus) 		5 / 12 GLY A 141
ASP A 108
LEU A 107
VAL A  78
VAL A  74
 None
 1.11A 5dpdB-3tcrA:
2.0		 5dpdB-3tcrA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 3tcr MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
(Mycobacteroides
abscessus) 		5 / 12 VAL A  28
ALA A  99
VAL A  30
LEU A 107
ILE A 114
 None
 0.98A 5hv1A-3tcrA:
undetectable		 5hv1A-3tcrA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 3tcr MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
(Mycobacteroides
abscessus) 		5 / 12 VAL A  28
PRO A 100
ALA A  99
VAL A  30
ILE A 114
 None
 1.21A 5hv1A-3tcrA:
undetectable		 5hv1A-3tcrA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 3tcr MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
(Mycobacteroides
abscessus) 		5 / 9 ALA A 154
ASP A 157
ILE A 118
GLY A 131
PRO A 100
 None
 1.19A 5kr2A-3tcrA:
undetectable		 5kr2A-3tcrA:
20.92