SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tcv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3tcv GCN5-RELATED
N-ACETYLTRANSFERASE
(Brucella
abortus) 		4 / 6 PHE A 135
LEU A 195
PRO A 193
GLU A 191
 None
 1.00A 3vlnA-3tcvA:
undetectable		 3vlnA-3tcvA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 3tcv GCN5-RELATED
N-ACETYLTRANSFERASE
(Brucella
abortus) 		5 / 12 TYR A 133
LEU A 138
GLY A 139
TYR A 140
PHE A  18
 None
 1.16A 3vywC-3tcvA:
undetectable		 3vywC-3tcvA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 3tcv GCN5-RELATED
N-ACETYLTRANSFERASE
(Brucella
abortus) 		4 / 7 ILE A 117
ALA A  91
VAL A  90
ALA A 126
 None
 0.82A 4g77A-3tcvA:
undetectable		 4g77A-3tcvA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3tcv GCN5-RELATED
N-ACETYLTRANSFERASE
(Brucella
abortus) 		4 / 7 PHE A 221
PRO A 205
TRP A 202
PHE A 208
 None
 1.35A 4grqA-3tcvA:
undetectable
4grqC-3tcvA:
undetectable		 4grqA-3tcvA:
16.59
4grqC-3tcvA:
16.59