SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tdf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3tdf DIHYDRODIPICOLINATE
SYNTHASE
(Acinetobacter
baumannii) 		5 / 12 TYR A 184
GLY A 201
SER A  38
SER A 215
ILE A 222
 None
 1.20A 1nt2A-3tdfA:
undetectable		 1nt2A-3tdfA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3tdf DIHYDRODIPICOLINATE
SYNTHASE
(Acinetobacter
baumannii) 		5 / 12 TYR A 184
GLY A 201
SER A 215
ALA A 191
ASP A 200
 None
 1.02A 1nt2A-3tdfA:
undetectable		 1nt2A-3tdfA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3tdf DIHYDRODIPICOLINATE
SYNTHASE
(Acinetobacter
baumannii) 		4 / 5 VAL A 103
THR A 104
VAL A 141
GLY A 140
 None
 1.08A 2p2fA-3tdfA:
undetectable		 2p2fA-3tdfA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3tdf DIHYDRODIPICOLINATE
SYNTHASE
(Acinetobacter
baumannii) 		4 / 4 VAL A 103
THR A 104
VAL A 141
GLY A 140
 None
 1.09A 2p2fB-3tdfA:
undetectable		 2p2fB-3tdfA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3tdf DIHYDRODIPICOLINATE
SYNTHASE
(Acinetobacter
baumannii) 		5 / 12 SER A  49
ALA A  48
GLY A  76
TYR A 133
GLY A  78
 None
None
None
2KT  A 524 (-3.9A)
None
 1.11A 3f8wA-3tdfA:
undetectable		 3f8wA-3tdfA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3tdf DIHYDRODIPICOLINATE
SYNTHASE
(Acinetobacter
baumannii) 		5 / 12 SER A  49
ALA A  48
GLY A  76
TYR A 133
GLY A  78
 None
None
None
2KT  A 524 (-3.9A)
None
 1.09A 3f8wC-3tdfA:
undetectable		 3f8wC-3tdfA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3tdf DIHYDRODIPICOLINATE
SYNTHASE
(Acinetobacter
baumannii) 		5 / 12 TYR A 184
GLY A 201
SER A 215
ALA A 191
ASP A 200
 None
 1.06A 3id6C-3tdfA:
undetectable		 3id6C-3tdfA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3tdf DIHYDRODIPICOLINATE
SYNTHASE
(Acinetobacter
baumannii) 		5 / 12 ALA A 221
GLY A   4
SER A   5
MET A 214
ASP A 200
 None
 1.38A 3ou6D-3tdfA:
undetectable		 3ou6D-3tdfA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3tdf DIHYDRODIPICOLINATE
SYNTHASE
(Acinetobacter
baumannii) 		4 / 8 THR A  50
GLY A  17
GLY A  18
VAL A  19
 None
 0.73A 4qvvK-3tdfA:
undetectable
4qvvL-3tdfA:
undetectable		 4qvvK-3tdfA:
21.50
4qvvL-3tdfA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3tdf DIHYDRODIPICOLINATE
SYNTHASE
(Acinetobacter
baumannii) 		4 / 8 THR A  50
GLY A  17
GLY A  18
VAL A  19
 None
 0.73A 4qvvY-3tdfA:
undetectable
4qvvZ-3tdfA:
undetectable		 4qvvY-3tdfA:
21.50
4qvvZ-3tdfA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 3tdf DIHYDRODIPICOLINATE
SYNTHASE
(Acinetobacter
baumannii) 		5 / 5 LEU A 256
ALA A 207
THR A  36
VAL A  28
ILE A  39
 None
 1.49A 4xe3B-3tdfA:
undetectable		 4xe3B-3tdfA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3tdf DIHYDRODIPICOLINATE
SYNTHASE
(Acinetobacter
baumannii) 		5 / 7 LEU A 102
LEU A 130
ALA A 123
ALA A 125
ALA A  85
 None
 1.35A 4z90F-3tdfA:
undetectable
4z90G-3tdfA:
undetectable
4z90H-3tdfA:
undetectable
4z90J-3tdfA:
undetectable		 4z90F-3tdfA:
20.93
4z90G-3tdfA:
20.93
4z90H-3tdfA:
20.93
4z90J-3tdfA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3tdf DIHYDRODIPICOLINATE
SYNTHASE
(Acinetobacter
baumannii) 		5 / 12 LEU A 101
GLY A  76
LEU A  27
VAL A  28
ILE A  63
 None
 1.26A 6bxmA-3tdfA:
undetectable		 6bxmA-3tdfA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB7_A_PARA900_0
(AAC(3)-IIIB PROTEIN)		 3tdf DIHYDRODIPICOLINATE
SYNTHASE
(Acinetobacter
baumannii) 		5 / 10 ASN A 108
TYR A 119
HIS A 118
GLY A  78
GLU A  84
 None
 1.14A 6mb7A-3tdfA:
undetectable		 6mb7A-3tdfA:
15.11