SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3te6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3te6 REGULATORY PROTEIN
SIR3
(Saccharomyces
cerevisiae) 		3 / 3 GLY A 797
ASP A 581
ASN A 794
 None
 0.30A 1vq1A-3te6A:
undetectable		 1vq1A-3te6A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_2
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 3te6 REGULATORY PROTEIN
SIR3
(Saccharomyces
cerevisiae) 		4 / 4 TRP A 683
LEU A 646
VAL A 653
LYS A 657
 None
 1.26A 2hw2A-3te6A:
0.0		 2hw2A-3te6A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3te6 REGULATORY PROTEIN
SIR3
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 698
ALA A 615
ILE A 665
LEU A 664
VAL A 589
 None
 0.89A 3adxB-3te6A:
undetectable		 3adxB-3te6A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 3te6 REGULATORY PROTEIN
SIR3
(Saccharomyces
cerevisiae) 		5 / 10 ASP A 816
GLY A 821
GLY A 822
LEU A 828
ILE A 776
 None
 0.97A 3em4V-3te6A:
undetectable		 3em4V-3te6A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 3te6 REGULATORY PROTEIN
SIR3
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 592
LEU A 722
ASN A 723
ILE A 720
 None
 1.01A 3rfmA-3te6A:
undetectable		 3rfmA-3te6A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3te6 REGULATORY PROTEIN
SIR3
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 574
ILE A 693
ILE A 694
MET A 593
ILE A 665
 None
 0.88A 3zosA-3te6A:
undetectable		 3zosA-3te6A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3te6 REGULATORY PROTEIN
SIR3
(Saccharomyces
cerevisiae) 		5 / 12 SER A 599
THR A 598
ILE A 597
PHE A 608
TYR A 564
 None
 1.21A 6a93A-3te6A:
undetectable		 6a93A-3te6A:
23.43