SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3teb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		5 / 11 HIS A 254
ASN A  41
VAL A  40
ALA A  36
SER A 138
 None
 1.48A 2iyfA-3tebA:
undetectable		 2iyfA-3tebA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		4 / 6 HIS A 254
GLU A  90
ASP A 173
ASN A 142
 None
 1.18A 3vywA-3tebA:
3.0		 3vywA-3tebA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		4 / 7 GLY A 180
TYR A 185
ALA A 183
GLU A 186
 None
 0.91A 4hyfA-3tebA:
undetectable		 4hyfA-3tebA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		4 / 8 GLY A 180
TYR A 185
ALA A 183
GLU A 186
 None
 0.89A 4hyfB-3tebA:
undetectable		 4hyfB-3tebA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		4 / 8 GLY A 180
TYR A 185
ALA A 183
GLU A 186
 None
 0.90A 4hyfC-3tebA:
undetectable		 4hyfC-3tebA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		5 / 11 HIS A 254
ASN A  41
VAL A  40
ALA A  36
SER A 138
 None
 1.49A 4m83A-3tebA:
undetectable		 4m83A-3tebA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_B_ERYB501_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		5 / 11 HIS A 254
ASN A  41
VAL A  40
ALA A  36
SER A 138
 None
 1.50A 4m83B-3tebA:
undetectable		 4m83B-3tebA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		4 / 7 ASP A 173
GLN A  38
THR A   5
ILE A 257
 None
 0.91A 4pcuA-3tebA:
undetectable		 4pcuA-3tebA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		4 / 7 PHE A 174
ASP A 173
THR A   5
ILE A 257
 None
 1.09A 4pcuA-3tebA:
undetectable		 4pcuA-3tebA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		5 / 11 PHE A 174
ASP A 173
GLN A  38
THR A   5
ILE A 257
 None
 1.19A 4uuuA-3tebA:
undetectable
4uuuB-3tebA:
undetectable		 4uuuA-3tebA:
17.78
4uuuB-3tebA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		5 / 11 PHE A 174
ASP A 173
GLN A  38
THR A   5
ILE A 257
 None
 1.16A 4uuuB-3tebA:
undetectable		 4uuuB-3tebA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		5 / 11 ALA A  24
LEU A  23
GLU A 249
LYS A 248
LEU A   4
 None
 1.09A 4wg0K-3tebA:
undetectable
4wg0L-3tebA:
undetectable
4wg0M-3tebA:
undetectable		 4wg0K-3tebA:
3.85
4wg0L-3tebA:
3.85
4wg0M-3tebA:
3.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		3 / 3 CYH A 108
MET A 141
ASN A 142
 None
 1.09A 5qh8A-3tebA:
undetectable		 5qh8A-3tebA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		4 / 6 ILE A 155
MET A 151
ASN A 154
ASP A 150
 None
 1.45A 6dhbA-3tebA:
undetectable		 6dhbA-3tebA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 3teb ENDONUCLEASE/EXONUCL
EASE/PHOSPHATASE
(Leptotrichia
buccalis) 		4 / 6 ALA A  36
THR A 196
ILE A 261
PHE A 263
 None
 0.90A 6f8cA-3tebA:
undetectable		 6f8cA-3tebA:
18.36