SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tek'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 3tek THERMODBP-SINGLE
STRANDED DNA BINDING
PROTEIN
(Thermoproteus
tenax) 		4 / 8 SER A 119
ALA A 104
ARG A 107
LEU A 110
 None
 1.10A 2bxkA-3tekA:
2.2		 2bxkA-3tekA:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 3tek THERMODBP-SINGLE
STRANDED DNA BINDING
PROTEIN
(Thermoproteus
tenax) 		4 / 6 SER A  63
GLU A  12
SER A 119
GLN A 139
 None
 1.38A 2cl5B-3tekA:
undetectable		 2cl5B-3tekA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 3tek THERMODBP-SINGLE
STRANDED DNA BINDING
PROTEIN
(Thermoproteus
tenax) 		4 / 6 SER A  63
GLU A  12
SER A 119
GLN A 139
 None
 1.34A 2zvjA-3tekA:
undetectable		 2zvjA-3tekA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI1_A_B49A299_1
(CYCLIN-DEPENDENT
KINASE 2)		 3tek THERMODBP-SINGLE
STRANDED DNA BINDING
PROTEIN
(Thermoproteus
tenax) 		5 / 9 VAL A  60
PHE A  76
PHE A  68
ASP A 125
LEU A 124
 None
 1.06A 3ti1A-3tekA:
undetectable		 3ti1A-3tekA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3tek THERMODBP-SINGLE
STRANDED DNA BINDING
PROTEIN
(Thermoproteus
tenax) 		4 / 5 SER A  63
GLU A  12
SER A 119
GLN A 139
 None
 1.34A 5fhrB-3tekA:
undetectable		 5fhrB-3tekA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 3tek THERMODBP-SINGLE
STRANDED DNA BINDING
PROTEIN
(Thermoproteus
tenax) 		3 / 3 THR A  32
PRO A  46
ARG A  49
 None
 0.73A 5nd7B-3tekA:
undetectable		 5nd7B-3tekA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 3tek THERMODBP-SINGLE
STRANDED DNA BINDING
PROTEIN
(Thermoproteus
tenax) 		5 / 7 GLY A  38
GLY A  45
PRO A  46
GLY A  47
GLY A  48
 None
 1.05A 6ag0A-3tekA:
undetectable		 6ag0A-3tekA:
18.79