SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3teo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_A_ACTA3001_0 (BETA-CARBONIC ANHYDRASE)	3teo	CARBON DISULFIDE HYDROLASE (Acidianus sp. A1-3)	4 / 8	ASP A 37 HIS A 88 CYH A 91 GLY A 92	None CL A 205 (-4.6A) CL A 205 ( 4.7A) None	0.38A	1ekjA-3teoA: 12.4 1ekjB-3teoA: 8.4	1ekjA-3teoA: 24.07 1ekjB-3teoA: 24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_A_ACTA3003_0 (BETA-CARBONIC ANHYDRASE)	3teo	CARBON DISULFIDE HYDROLASE (Acidianus sp. A1-3)	5 / 8	CYH A 35 ASP A 37 HIS A 88 CYH A 91 GLY A 92	CL A 205 (-4.3A) None CL A 205 (-4.6A) CL A 205 ( 4.7A) None	0.92A	1ekjA-3teoA: 12.4 1ekjB-3teoA: 8.4	1ekjA-3teoA: 24.07 1ekjB-3teoA: 24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_E_ACTE3005_0 (BETA-CARBONIC ANHYDRASE)	3teo	CARBON DISULFIDE HYDROLASE (Acidianus sp. A1-3)	4 / 7	ASP A 37 HIS A 88 GLY A 60 GLY A 61	None CL A 205 (-4.6A) CL A 205 (-3.9A) None	0.95A	1ekjE-3teoA: 11.3 1ekjF-3teoA: 12.3	1ekjE-3teoA: 24.07 1ekjF-3teoA: 24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_G_ACTG3002_0 (BETA-CARBONIC ANHYDRASE)	3teo	CARBON DISULFIDE HYDROLASE (Acidianus sp. A1-3)	5 / 8	CYH A 35 ASP A 37 HIS A 88 CYH A 91 GLY A 92	CL A 205 (-4.3A) None CL A 205 (-4.6A) CL A 205 ( 4.7A) None	1.02A	1ekjG-3teoA: 12.9 1ekjH-3teoA: 9.5	1ekjG-3teoA: 24.07 1ekjH-3teoA: 24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EKJ_H_ACTH3006_0 (BETA-CARBONIC ANHYDRASE)	3teo	CARBON DISULFIDE HYDROLASE (Acidianus sp. A1-3)	4 / 6	CYH A 35 ASP A 37 HIS A 88 CYH A 91	CL A 205 (-4.3A) None CL A 205 (-4.6A) CL A 205 ( 4.7A)	1.12A	1ekjG-3teoA: 12.9 1ekjH-3teoA: 12.4	1ekjG-3teoA: 24.07 1ekjH-3teoA: 24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K2H_B_LYAB514_2 (DIHYDROFOLATE REDUCTASE/THYMIDYLAT E SYNTHASE)	3teo	CARBON DISULFIDE HYDROLASE (Acidianus sp. A1-3)	3 / 3	ARG A 57 THR A 75 THR A 64	None	0.76A	3k2hB-3teoA: undetectable	3k2hB-3teoA: 18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LB3_A_4CHA191_0 (DEHALOPEROXIDASE A)	3teo	CARBON DISULFIDE HYDROLASE (Acidianus sp. A1-3)	4 / 6	TYR A 139 HIS A 88 THR A 87 VAL A 174	None CL A 205 (-4.6A) None None	1.02A	3lb3A-3teoA: undetectable	3lb3A-3teoA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LB3_B_4CHB192_0 (DEHALOPEROXIDASE A)	3teo	CARBON DISULFIDE HYDROLASE (Acidianus sp. A1-3)	4 / 6	TYR A 139 HIS A 88 THR A 87 VAL A 174	None CL A 205 (-4.6A) None None	1.03A	3lb3B-3teoA: undetectable	3lb3B-3teoA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UCJ_A_AZMA229_1 (CARBONIC ANHYDRASE)	3teo	CARBON DISULFIDE HYDROLASE (Acidianus sp. A1-3)	5 / 10	CYH A 35 ASP A 37 HIS A 88 CYH A 91 GLY A 92	CL A 205 (-4.3A) None CL A 205 (-4.6A) CL A 205 ( 4.7A) None	0.93A	3ucjA-3teoA: 13.1	3ucjA-3teoA: 24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UCJ_B_AZMB229_2 (CARBONIC ANHYDRASE)	3teo	CARBON DISULFIDE HYDROLASE (Acidianus sp. A1-3)	5 / 10	CYH A 35 ASP A 37 HIS A 88 CYH A 91 GLY A 92	CL A 205 (-4.3A) None CL A 205 (-4.6A) CL A 205 ( 4.7A) None	0.93A	3ucjB-3teoA: 13.5	3ucjB-3teoA: 24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RVG_A_SAMA503_0 (D-MYCAROSE 3-C-METHYLTRANSFERAS E)	3teo	CARBON DISULFIDE HYDROLASE (Acidianus sp. A1-3)	5 / 12	THR A 87 ILE A 157 GLY A 154 VAL A 63 ILE A 68	None	0.92A	4rvgA-3teoA: undetectable	4rvgA-3teoA: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4USW_A_ACTA1470_0 (ADENYLATE CYCLASE TYPE 10)	3teo	CARBON DISULFIDE HYDROLASE (Acidianus sp. A1-3)	4 / 6	LEU A 94 LEU A 142 VAL A 144 PHE A 138	None	1.09A	4uswA-3teoA: undetectable	4uswA-3teoA: 20.13

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EKJ_A_ACTA3001_0","BETA-CARBONIC ANHYDRASE","3teo","CARBON DISULFIDE HYDROLASE","Acidianus sp. A1-3",4,"ASP A  37;HIS A  88;CYH A  91;GLY A  92","None; CL A 205 (-4.6A); CL A 205 ( 4.7A);None","0.38A","1ekjA-3teoA:12.4;1ekjB-3teoA:8.4","1ekjA-3teoA:24.07;1ekjB-3teoA:24.07"],["1EKJ_A_ACTA3003_0","BETA-CARBONIC ANHYDRASE","3teo","CARBON DISULFIDE HYDROLASE","Acidianus sp. A1-3",5,"CYH A  35;ASP A  37;HIS A  88;CYH A  91;GLY A  92"," CL A 205 (-4.3A);None; CL A 205 (-4.6A); CL A 205 ( 4.7A);None","0.92A","1ekjA-3teoA:12.4;1ekjB-3teoA:8.4","1ekjA-3teoA:24.07;1ekjB-3teoA:24.07"],["1EKJ_E_ACTE3005_0","BETA-CARBONIC ANHYDRASE","3teo","CARBON DISULFIDE HYDROLASE","Acidianus sp. A1-3",4,"ASP A  37;HIS A  88;GLY A  60;GLY A  61","None; CL A 205 (-4.6A); CL A 205 (-3.9A);None","0.95A","1ekjE-3teoA:11.3;1ekjF-3teoA:12.3","1ekjE-3teoA:24.07;1ekjF-3teoA:24.07"],["1EKJ_G_ACTG3002_0","BETA-CARBONIC ANHYDRASE","3teo","CARBON DISULFIDE HYDROLASE","Acidianus sp. A1-3",5,"CYH A  35;ASP A  37;HIS A  88;CYH A  91;GLY A  92"," CL A 205 (-4.3A);None; CL A 205 (-4.6A); CL A 205 ( 4.7A);None","1.02A","1ekjG-3teoA:12.9;1ekjH-3teoA:9.5","1ekjG-3teoA:24.07;1ekjH-3teoA:24.07"],["1EKJ_H_ACTH3006_0","BETA-CARBONIC ANHYDRASE","3teo","CARBON DISULFIDE HYDROLASE","Acidianus sp. A1-3",4,"CYH A  35;ASP A  37;HIS A  88;CYH A  91"," CL A 205 (-4.3A);None; CL A 205 (-4.6A); CL A 205 ( 4.7A)","1.12A","1ekjG-3teoA:12.9;1ekjH-3teoA:12.4","1ekjG-3teoA:24.07;1ekjH-3teoA:24.07"],["3K2H_B_LYAB514_2","DIHYDROFOLATE REDUCTASE\/THYMIDYLATE SYNTHASE","3teo","CARBON DISULFIDE HYDROLASE","Acidianus sp. A1-3",3,"ARG A  57;THR A  75;THR A  64","None","0.76A","3k2hB-3teoA:undetectable","3k2hB-3teoA:18.27"],["3LB3_A_4CHA191_0","DEHALOPEROXIDASE A","3teo","CARBON DISULFIDE HYDROLASE","Acidianus sp. A1-3",4,"TYR A 139;HIS A  88;THR A  87;VAL A 174","None; CL A 205 (-4.6A);None;None","1.02A","3lb3A-3teoA:undetectable","3lb3A-3teoA:20.00"],["3LB3_B_4CHB192_0","DEHALOPEROXIDASE A","3teo","CARBON DISULFIDE HYDROLASE","Acidianus sp. A1-3",4,"TYR A 139;HIS A  88;THR A  87;VAL A 174","None; CL A 205 (-4.6A);None;None","1.03A","3lb3B-3teoA:undetectable","3lb3B-3teoA:20.00"],["3UCJ_A_AZMA229_1","CARBONIC ANHYDRASE","3teo","CARBON DISULFIDE HYDROLASE","Acidianus sp. A1-3",5,"CYH A  35;ASP A  37;HIS A  88;CYH A  91;GLY A  92"," CL A 205 (-4.3A);None; CL A 205 (-4.6A); CL A 205 ( 4.7A);None","0.93A","3ucjA-3teoA:13.1","3ucjA-3teoA:24.59"],["3UCJ_B_AZMB229_2","CARBONIC ANHYDRASE","3teo","CARBON DISULFIDE HYDROLASE","Acidianus sp. A1-3",5,"CYH A  35;ASP A  37;HIS A  88;CYH A  91;GLY A  92"," CL A 205 (-4.3A);None; CL A 205 (-4.6A); CL A 205 ( 4.7A);None","0.93A","3ucjB-3teoA:13.5","3ucjB-3teoA:24.59"],["4RVG_A_SAMA503_0","D-MYCAROSE 3-C-METHYLTRANSFERASE","3teo","CARBON DISULFIDE HYDROLASE","Acidianus sp. A1-3",5,"THR A  87;ILE A 157;GLY A 154;VAL A  63;ILE A  68","None","0.92A","4rvgA-3teoA:undetectable","4rvgA-3teoA:19.05"],["4USW_A_ACTA1470_0","ADENYLATE CYCLASE TYPE 10","3teo","CARBON DISULFIDE HYDROLASE","Acidianus sp. A1-3",4,"LEU A  94;LEU A 142;VAL A 144;PHE A 138","None","1.09A","4uswA-3teoA:undetectable","4uswA-3teoA:20.13"]]