SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tev'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		4 / 5 LEU A 162
VAL A  44
LEU A  46
ARG A  65
 None
 1.10A 2oiqA-3tevA:
undetectable		 2oiqA-3tevA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		3 / 3 ARG A  65
GLU A  66
GLN A 331
 None
 0.85A 2p16A-3tevA:
undetectable		 2p16A-3tevA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		3 / 3 SER A 260
THR A 236
PHE A 209
 None
 0.70A 2x91A-3tevA:
undetectable		 2x91A-3tevA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		3 / 3 TYR A 226
GLU A 205
ASN A 136
 None
 1.00A 2y7hC-3tevA:
undetectable		 2y7hC-3tevA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		4 / 6 ILE A  74
VAL A  44
LEU A  23
LEU A  28
 None
 0.85A 3kp6A-3tevA:
undetectable
3kp6B-3tevA:
0.7		 3kp6A-3tevA:
17.56
3kp6B-3tevA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		4 / 6 ILE A 133
ALA A 151
THR A 155
ALA A 211
 None
 0.89A 3mdrB-3tevA:
undetectable		 3mdrB-3tevA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		5 / 10 THR A 107
ASN A 111
HIS A 165
GLY A 158
ALA A 160
 None
 1.30A 3pp7B-3tevA:
6.2		 3pp7B-3tevA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		4 / 8 LEU A 280
VAL A 303
VAL A 307
GLN A 311
 None
 0.73A 4em2A-3tevA:
undetectable		 4em2A-3tevA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		3 / 3 CYH A 173
ASN A 126
LYS A 175
 None
 1.11A 4k50A-3tevA:
undetectable		 4k50A-3tevA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		3 / 3 VAL A 295
THR A 299
ARG A 272
 None
 0.77A 5b2sB-3tevA:
undetectable		 5b2sB-3tevA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		3 / 3 VAL A 295
THR A 299
ARG A 272
 None
 0.77A 5b2tB-3tevA:
undetectable		 5b2tB-3tevA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		6 / 12 ILE A 256
GLY A 254
ASP A 253
ARG A 247
LEU A 131
ALA A 174
 None
 1.30A 5h5fA-3tevA:
undetectable		 5h5fA-3tevA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		5 / 10 THR A 107
ALA A  95
ALA A 160
GLY A 158
ASP A 132
 None
 1.22A 5lf3H-3tevA:
undetectable
5lf3I-3tevA:
undetectable		 5lf3H-3tevA:
20.87
5lf3I-3tevA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		5 / 10 THR A 107
ALA A  95
ALA A 160
GLY A 158
ASP A 132
 None
 1.22A 5lf3V-3tevA:
undetectable
5lf3W-3tevA:
undetectable		 5lf3V-3tevA:
20.87
5lf3W-3tevA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M6G_A_SORA711_0
(BETA-GLUCOSIDASE)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		6 / 12 ASP A  77
PHE A 127
LYS A 175
HIS A 176
MET A 220
MET A 288
 None
 0.79A 5m6gA-3tevA:
28.9		 5m6gA-3tevA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		4 / 8 ALA A  43
LEU A  23
VAL A  67
MET A  68
 None
 0.78A 5nujA-3tevA:
undetectable		 5nujA-3tevA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		5 / 9 MET A  20
LEU A  73
VAL A 255
ILE A 219
PHE A 127
 None
 1.16A 5tixA-3tevA:
0.0		 5tixA-3tevA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 3tev GLYCOSYL HYROLASE,
FAMILY 3
(Deinococcus
radiodurans) 		4 / 5 ARG A 198
ALA A 228
TYR A 226
ILE A 241
 None
 1.41A 6g9bA-3tevA:
undetectable
6g9bB-3tevA:
undetectable		 6g9bA-3tevA:
15.41
6g9bB-3tevA:
13.29