SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tex'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		5 / 12 LEU A 450
LEU A 385
GLN A 438
LEU A 421
THR A 381
 None
 1.22A 1a28B-3texA:
undetectable		 1a28B-3texA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		5 / 12 LEU A 450
LEU A 448
LEU A 385
LEU A 421
THR A 381
 None
 1.31A 1a28B-3texA:
undetectable		 1a28B-3texA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		5 / 11 LEU A 450
LEU A 271
LEU A 421
VAL A 332
ILE A 269
 None
 1.05A 1ee2A-3texA:
undetectable		 1ee2A-3texA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		5 / 11 LEU A 450
LEU A 271
LEU A 421
VAL A 332
ILE A 269
 None
 1.01A 1ee2B-3texA:
undetectable		 1ee2B-3texA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 8 SER A 221
TYR A 192
TYR A  22
VAL A 175
 CA  A 801 ( 4.6A)
None
None
None
 1.06A 1fduB-3texA:
undetectable		 1fduB-3texA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 8 GLU A 535
ASP A 546
ILE A 547
THR A 548
 None
 0.80A 1hmyA-3texA:
undetectable		 1hmyA-3texA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_D_MTXD354_1
(PTERIDINE REDUCTASE
1)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		5 / 12 SER A 234
PHE A 236
PRO A 154
LEU A 187
PRO A 184
 None
 1.45A 1p33D-3texA:
undetectable		 1p33D-3texA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		5 / 10 ILE A 726
VAL A 701
TYR A 699
GLY A 641
LEU A 627
 None
 1.39A 1s1uA-3texA:
undetectable		 1s1uA-3texA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 5 ILE A 665
SER A 717
ARG A 659
LEU A 663
 None
 1.18A 1y0xX-3texA:
undetectable		 1y0xX-3texA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 8 LEU A 187
GLY A 191
LEU A 203
PRO A 254
 None
 0.69A 1ya4A-3texA:
undetectable		 1ya4A-3texA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 7 LEU A 187
GLY A 191
LEU A 203
PRO A 254
 None
 0.60A 1ya4B-3texA:
undetectable		 1ya4B-3texA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		3 / 3 LYS A 545
ASP A 599
ASP A 593
 None
 1.02A 2br4D-3texA:
undetectable		 2br4D-3texA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 6 LEU A 187
LEU A 203
PRO A 254
VAL A 239
 None
 0.94A 2dqyC-3texA:
undetectable		 2dqyC-3texA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 7 ASP A 520
SER A 221
GLU A 188
ASP A 185
 None
CA  A 801 ( 4.6A)
CA  A 801 ( 2.4A)
None
 1.17A 3bc9A-3texA:
4.7		 3bc9A-3texA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		6 / 12 ASP A 546
LEU A 540
ILE A 591
ASP A 551
LEU A 578
LEU A 523
 None
 1.34A 3cjtC-3texA:
undetectable		 3cjtC-3texA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 7 PHE A 236
VAL A 194
ARG A 242
VAL A  35
 None
 1.31A 3dqrA-3texA:
undetectable
3dqrB-3texA:
undetectable		 3dqrA-3texA:
20.82
3dqrB-3texA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		3 / 3 ILE A 591
PHE A 531
HIS A 299
 None
 0.59A 3h0aA-3texA:
undetectable		 3h0aA-3texA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 8 SER A 234
PHE A 236
LEU A 187
PRO A 184
 None
 1.19A 3jq7B-3texA:
undetectable		 3jq7B-3texA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 6 VAL A 194
ARG A 242
VAL A  35
PHE A 236
 None
 1.42A 3jx4A-3texA:
undetectable
3jx4B-3texA:
undetectable		 3jx4A-3texA:
20.82
3jx4B-3texA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 5 SER A  38
ARG A 200
GLY A 129
GLU A 127
 None
 1.23A 3k9fA-3texA:
undetectable
3k9fB-3texA:
undetectable
3k9fC-3texA:
undetectable		 3k9fA-3texA:
21.20
3k9fB-3texA:
21.20
3k9fC-3texA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		3 / 3 ASN A 368
ASN A 328
GLU A 502
 None
 0.89A 3kpdC-3texA:
undetectable		 3kpdC-3texA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		5 / 11 THR A 228
THR A 488
ALA A 489
SER A 222
SER A 230
 None
 1.22A 3mg0N-3texA:
undetectable		 3mg0N-3texA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 7 PHE A 236
VAL A 194
ARG A 242
VAL A  35
 None
 1.30A 3nlqA-3texA:
undetectable
3nlqB-3texA:
undetectable		 3nlqA-3texA:
20.82
3nlqB-3texA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		5 / 11 LEU A 523
PHE A 552
TYR A 575
LEU A 540
ILE A 547
 None
 1.09A 3o94B-3texA:
undetectable		 3o94B-3texA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		5 / 12 ILE A 656
PHE A 678
ILE A 689
ILE A 734
VAL A 619
 None
 1.17A 3w68C-3texA:
undetectable		 3w68C-3texA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		3 / 3 HIS A 336
TRP A 346
SER A 640
 None
 1.00A 4lrhD-3texA:
undetectable		 4lrhD-3texA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		3 / 3 GLU A 502
ARG A 297
GLN A 485
 None
 0.87A 4rtbA-3texA:
undetectable		 4rtbA-3texA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 5 ARG A 200
GLY A 129
GLU A 127
SER A  38
 None
 1.21A 4z3oA-3texA:
undetectable
4z3oB-3texA:
undetectable		 4z3oA-3texA:
22.75
4z3oB-3texA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 6 VAL A 194
ARG A 242
VAL A  35
PHE A 236
 None
 1.39A 5addA-3texA:
undetectable
5addB-3texA:
undetectable		 5addA-3texA:
20.82
5addB-3texA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 6 VAL A 194
ARG A 242
VAL A  35
PHE A 236
 None
 1.44A 5adeA-3texA:
undetectable
5adeB-3texA:
undetectable		 5adeA-3texA:
20.82
5adeB-3texA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 7 ARG A 200
SER A  38
GLY A 129
GLU A 127
 None
 0.99A 5btaA-3texA:
undetectable
5btaC-3texA:
undetectable
5btaD-3texA:
undetectable		 5btaA-3texA:
21.37
5btaC-3texA:
21.37
5btaD-3texA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 6 SER A  38
GLY A 129
GLU A 127
ARG A 200
 None
 0.98A 5btaA-3texA:
undetectable
5btaB-3texA:
undetectable
5btaC-3texA:
1.6		 5btaA-3texA:
21.37
5btaB-3texA:
15.45
5btaC-3texA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 6 ARG A 200
SER A  38
GLY A 129
GLU A 127
 None
 0.95A 5btcA-3texA:
undetectable
5btcC-3texA:
undetectable
5btcD-3texA:
undetectable		 5btcA-3texA:
21.37
5btcC-3texA:
21.37
5btcD-3texA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 6 SER A  38
GLY A 129
GLU A 127
ARG A 200
 None
 0.95A 5btcA-3texA:
undetectable
5btcB-3texA:
undetectable
5btcC-3texA:
undetectable		 5btcA-3texA:
21.37
5btcB-3texA:
15.45
5btcC-3texA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 5 SER A  38
GLY A 129
GLU A 127
ARG A 200
 None
 1.17A 5cdqA-3texA:
undetectable
5cdqB-3texA:
undetectable
5cdqC-3texA:
undetectable		 5cdqA-3texA:
21.02
5cdqB-3texA:
14.22
5cdqC-3texA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 5 SER A  38
GLY A 129
GLU A 127
ARG A 200
 None
 1.11A 5cdqR-3texA:
undetectable
5cdqS-3texA:
undetectable
5cdqT-3texA:
undetectable		 5cdqR-3texA:
21.02
5cdqS-3texA:
14.22
5cdqT-3texA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		5 / 12 GLY A 626
ILE A 665
ILE A 620
ASN A 621
ASN A 630
 None
 1.07A 5fa8A-3texA:
undetectable		 5fa8A-3texA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 4 THR A 702
LEU A 639
HIS A 616
GLY A 641
 None
 1.39A 5gwyA-3texA:
undetectable		 5gwyA-3texA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		5 / 9 PRO A 407
VAL A 480
LEU A 481
ILE A 484
LEU A 378
 None
 1.29A 5iepA-3texA:
undetectable		 5iepA-3texA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 6 PRO A 154
GLY A 182
PHE A 464
ARG A 242
 None
 1.46A 5jcnB-3texA:
undetectable		 5jcnB-3texA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 8 THR A 488
SER A 230
SER A 227
ALA A 258
 None
 1.08A 5l5fY-3texA:
undetectable
5l5fZ-3texA:
undetectable		 5l5fY-3texA:
13.72
5l5fZ-3texA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		3 / 3 ALA A 257
GLN A 485
THR A 488
 None
 0.53A 5n0oA-3texA:
undetectable		 5n0oA-3texA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		3 / 3 VAL A  91
TYR A 114
GLN A 115
 None
 0.68A 5qgkA-3texA:
undetectable		 5qgkA-3texA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		3 / 3 VAL A  91
TYR A 114
GLN A 115
 None
 0.67A 5qgrA-3texA:
undetectable		 5qgrA-3texA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		3 / 3 VAL A  91
TYR A 114
GLN A 115
 None
 0.73A 5qgtA-3texA:
undetectable		 5qgtA-3texA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		5 / 12 LEU A 523
PHE A 552
ILE A 491
PHE A 493
GLU A 535
 None
 1.00A 5veuH-3texA:
undetectable		 5veuH-3texA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 3tex PROTECTIVE ANTIGEN
(Bacillus
anthracis) 		4 / 4 ILE A 635
LEU A 498
HIS A 597
ALA A 604
 None
 0.89A 6ck2C-3texA:
undetectable
6ck2D-3texA:
undetectable		 6ck2C-3texA:
3.02
6ck2D-3texA:
5.22