SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tf7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3tf7 42F3 MUT7 SCFV (42F3
ALPHA CHAIN, LINKER,
42F3 BETA CHAIN)
(Mus
musculus) 		5 / 12 LEU C 233
SER C 227
SER C  99
SER C  93
LEU C 209
 None
None
GOL  C 254 ( 3.9A)
None
None
 1.41A 2zlcA-3tf7C:
undetectable		 2zlcA-3tf7C:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 3tf7 42F3 MUT7 SCFV (42F3
ALPHA CHAIN, LINKER,
42F3 BETA CHAIN)
(Mus
musculus) 		3 / 3 ASP C  70
SER C  72
ARG C  21
 None
 0.96A 3loqA-3tf7C:
undetectable		 3loqA-3tf7C:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3tf7 42F3 MUT7 SCFV (42F3
ALPHA CHAIN, LINKER,
42F3 BETA CHAIN)
(Mus
musculus) 		3 / 3 TYR C 181
GLY C 191
ASP C 192
 None
 0.56A 3ou6C-3tf7C:
undetectable		 3ou6C-3tf7C:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_E_ACHE301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3tf7 42F3 MUT7 SCFV (42F3
ALPHA CHAIN, LINKER,
42F3 BETA CHAIN)
(Mus
musculus) 		4 / 8 TRP C 167
TYR C 197
THR C 153
TYR C 222
 None
 1.35A 3wipA-3tf7C:
undetectable
3wipE-3tf7C:
undetectable		 3wipA-3tf7C:
22.10
3wipE-3tf7C:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 3tf7 42F3 MUT7 SCFV (42F3
ALPHA CHAIN, LINKER,
42F3 BETA CHAIN)
(Mus
musculus) 		4 / 7 SER C  71
ASP C  70
SER C  72
PHE C  66
 None
 0.92A 4ac9C-3tf7C:
undetectable		 4ac9C-3tf7C:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3tf7 42F3 MUT7 SCFV (42F3
ALPHA CHAIN, LINKER,
42F3 BETA CHAIN)
(Mus
musculus) 		4 / 4 TYR C  35
GLY C  98
SER C  93
LEU C 101
 None
 1.45A 5bphC-3tf7C:
undetectable		 5bphC-3tf7C:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 3tf7 42F3 MUT7 SCFV (42F3
ALPHA CHAIN, LINKER,
42F3 BETA CHAIN)
(Mus
musculus) 		3 / 3 SER C  51
TYR C  50
TYR C  49
 None
 0.50A 5lakA-3tf7C:
undetectable
5lakI-3tf7C:
undetectable		 5lakA-3tf7C:
21.84
5lakI-3tf7C:
2.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 3tf7 42F3 MUT7 SCFV (42F3
ALPHA CHAIN, LINKER,
42F3 BETA CHAIN)
(Mus
musculus) 		3 / 3 SER C  51
TYR C  50
TYR C  49
 None
 0.34A 5lakC-3tf7C:
undetectable
5lakJ-3tf7C:
undetectable		 5lakC-3tf7C:
21.84
5lakJ-3tf7C:
2.08