SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tfm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3tfm MYOSIN X
(Rattus
norvegicus) 		4 / 7 LYS A  33
LEU A  32
PHE A  11
LEU A 212
 None
 1.04A 1v55C-3tfmA:
undetectable
1v55J-3tfmA:
undetectable		 1v55C-3tfmA:
20.15
1v55J-3tfmA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3tfm MYOSIN X
(Rattus
norvegicus) 		4 / 7 LYS A  33
LEU A  32
PHE A  11
LEU A 212
 None
 1.02A 2eijC-3tfmA:
undetectable
2eijJ-3tfmA:
undetectable		 2eijC-3tfmA:
20.15
2eijJ-3tfmA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3tfm MYOSIN X
(Rattus
norvegicus) 		4 / 7 LYS A  33
LEU A  32
PHE A  11
LEU A 212
 None
 1.06A 2eimC-3tfmA:
undetectable
2eimJ-3tfmA:
undetectable		 2eimC-3tfmA:
20.15
2eimJ-3tfmA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3tfm MYOSIN X
(Rattus
norvegicus) 		5 / 12 ILE A 114
LEU A  79
SER A 132
GLN A 133
ILE A 112
 None
 1.30A 2ogyA-3tfmA:
undetectable		 2ogyA-3tfmA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 3tfm MYOSIN X
(Rattus
norvegicus) 		3 / 3 LYS A   9
VAL A  31
HIS A  12
 None
 0.97A 3tj7A-3tfmA:
undetectable		 3tj7A-3tfmA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3tfm MYOSIN X
(Rattus
norvegicus) 		3 / 3 ASP A 113
VAL A  96
ASN A  55
 None
 0.80A 4lmnA-3tfmA:
undetectable		 4lmnA-3tfmA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3tfm MYOSIN X
(Rattus
norvegicus) 		4 / 6 ILE A 103
GLY A  58
ASN A  55
ILE A 115
 None
 0.96A 5j4nB-3tfmA:
undetectable		 5j4nB-3tfmA:
17.84