SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tg9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		5 / 12 ALA A  62
LEU A 242
ALA A 241
PHE A  58
LEU A  57
 None
 1.23A 1g5yB-3tg9A:
undetectable		 1g5yB-3tg9A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		4 / 6 HIS A  92
ILE A  91
ALA A  62
VAL A 161
 None
 1.06A 1hk1A-3tg9A:
undetectable		 1hk1A-3tg9A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		3 / 3 VAL A 310
ALA A  18
HIS A  45
 None
 0.75A 1q23G-3tg9A:
undetectable		 1q23G-3tg9A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		3 / 3 VAL A 310
ALA A  18
HIS A  45
 None
 0.77A 1q23L-3tg9A:
undetectable		 1q23L-3tg9A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		4 / 6 ALA A  18
LEU A  19
SER A  31
CYH A 295
 None
 1.05A 1sbrA-3tg9A:
undetectable
1sbrB-3tg9A:
undetectable		 1sbrA-3tg9A:
21.80
1sbrB-3tg9A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		4 / 6 ALA A 228
VAL A 174
GLU A 175
PHE A 179
 None
 0.59A 2cizA-3tg9A:
undetectable		 2cizA-3tg9A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		4 / 8 ILE A  26
ALA A 232
HIS A  46
GLU A 233
 None
 0.92A 2x0pA-3tg9A:
undetectable		 2x0pA-3tg9A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		4 / 5 VAL A 165
VAL A 162
GLN A  65
ARG A 181
 None
 1.36A 3bjwH-3tg9A:
undetectable		 3bjwH-3tg9A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		4 / 5 VAL A 165
VAL A 162
GLN A  65
ARG A 181
 None
 1.32A 3bjwB-3tg9A:
undetectable		 3bjwB-3tg9A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		4 / 7 LEU A 247
ARG A 244
SER A 187
MET A 235
 None
 1.26A 4klrA-3tg9A:
undetectable		 4klrA-3tg9A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		4 / 8 GLY A 226
THR A  59
TRP A 274
PHE A 155
 None
 1.25A 4m5mA-3tg9A:
undetectable		 4m5mA-3tg9A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		5 / 10 ASP A 234
ALA A 200
GLY A 188
PHE A 190
GLY A  50
 None
 1.07A 4mmdA-3tg9A:
undetectable		 4mmdA-3tg9A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		5 / 12 ASP A 234
ALA A 200
GLY A 188
PHE A 190
GLY A  50
 None
 1.08A 4mmdB-3tg9A:
undetectable		 4mmdB-3tg9A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		4 / 4 VAL A 310
ALA A 312
ASN A 313
GLN A 314
 None
 1.30A 4zgfA-3tg9A:
undetectable		 4zgfA-3tg9A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		5 / 12 GLY A 159
LEU A 128
VAL A 120
GLY A 223
LEU A 158
 None
 1.17A 5hg0A-3tg9A:
undetectable		 5hg0A-3tg9A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		5 / 12 PHE A 155
TYR A 269
LEU A 256
PHE A  58
LEU A 238
 None
 1.15A 5iepA-3tg9A:
undetectable		 5iepA-3tg9A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		5 / 12 GLY A 227
GLY A 293
GLY A  50
LYS A 212
ASP A 291
 None
 0.88A 5ikmA-3tg9A:
undetectable		 5ikmA-3tg9A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		5 / 12 ILE A   8
GLY A  16
ALA A  18
ALA A 200
ALA A 312
 None
 1.04A 5zw4A-3tg9A:
undetectable		 5zw4A-3tg9A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		5 / 12 GLY A 159
ALA A  62
ASP A 225
ILE A 156
LEU A 128
 None
 1.02A 6b3aA-3tg9A:
undetectable		 6b3aA-3tg9A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		5 / 12 GLY A 159
ALA A  62
ASP A 225
ILE A 156
LEU A 128
 None
 0.96A 6b3bA-3tg9A:
undetectable		 6b3bA-3tg9A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 3tg9 PENICILLIN-BINDING
PROTEIN
(Bacillus
halodurans) 		3 / 3 ASP A 208
LEU A 206
ARG A  37
 None
 0.77A 7dfrA-3tg9A:
undetectable		 7dfrA-3tg9A:
18.26