SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tgv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3tgv HEME-BINDING PROTEIN
HUTZ
(Vibrio
cholerae) 		4 / 7 SER A 106
ARG A 137
GLN A 111
GLU A 107
 None
 1.17A 2c8aA-3tgvA:
undetectable		 2c8aA-3tgvA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3tgv HEME-BINDING PROTEIN
HUTZ
(Vibrio
cholerae) 		4 / 6 LEU A 138
GLN A 139
LEU A  28
PHE A  46
 None
 0.94A 3ag1C-3tgvA:
undetectable
3ag1J-3tgvA:
undetectable		 3ag1C-3tgvA:
20.08
3ag1J-3tgvA:
14.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 3tgv HEME-BINDING PROTEIN
HUTZ
(Vibrio
cholerae) 		4 / 4 LEU A  14
GLY A 150
LEU A 151
GLU A 152
 None
 0.26A 3tgvB-3tgvA:
27.3		 3tgvB-3tgvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 3tgv HEME-BINDING PROTEIN
HUTZ
(Vibrio
cholerae) 		6 / 6 ARG A  22
GLN A  48
TYR A  53
PHE A  95
PRO A 140
LEU A 144
 None
 0.67A 3tgvB-3tgvA:
27.3		 3tgvB-3tgvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 3tgv HEME-BINDING PROTEIN
HUTZ
(Vibrio
cholerae) 		4 / 6 GLN A  48
TYR A  53
PHE A  95
LEU A  93
 None
 1.45A 3tgvB-3tgvA:
27.3		 3tgvB-3tgvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TGV_C_BEZC1_0
(HEME-BINDING PROTEIN
HUTZ)		 3tgv HEME-BINDING PROTEIN
HUTZ
(Vibrio
cholerae) 		5 / 5 ARG A  22
TYR A  53
PHE A  95
PRO A 140
LEU A 144
 None
 0.23A 3tgvC-3tgvA:
27.8		 3tgvC-3tgvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 3tgv HEME-BINDING PROTEIN
HUTZ
(Vibrio
cholerae) 		6 / 6 ARG A  22
GLN A  48
TYR A  53
PHE A  95
PRO A 140
LEU A 144
 None
 0.60A 3tgvD-3tgvA:
27.2		 3tgvD-3tgvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 3tgv HEME-BINDING PROTEIN
HUTZ
(Vibrio
cholerae) 		4 / 6 GLN A  48
TYR A  53
PHE A  95
LEU A  93
 None
 1.34A 3tgvD-3tgvA:
27.2		 3tgvD-3tgvA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 3tgv HEME-BINDING PROTEIN
HUTZ
(Vibrio
cholerae) 		4 / 6 GLY A 121
GLU A 122
PHE A 120
ILE A 113
 None
 0.92A 5kmfA-3tgvA:
undetectable
5kmfC-3tgvA:
undetectable		 5kmfA-3tgvA:
18.56
5kmfC-3tgvA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3tgv HEME-BINDING PROTEIN
HUTZ
(Vibrio
cholerae) 		3 / 3 MET A  76
GLN A  29
ARG A  25
 None
 1.07A 5m35B-3tgvA:
undetectable		 5m35B-3tgvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3tgv HEME-BINDING PROTEIN
HUTZ
(Vibrio
cholerae) 		3 / 3 MET A  76
GLN A  29
ARG A  25
 None
 1.07A 5m36A-3tgvA:
undetectable		 5m36A-3tgvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3tgv HEME-BINDING PROTEIN
HUTZ
(Vibrio
cholerae) 		3 / 3 MET A  76
GLN A  29
ARG A  25
 None
 1.06A 6fn9A-3tgvA:
undetectable		 6fn9A-3tgvA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3tgv HEME-BINDING PROTEIN
HUTZ
(Vibrio
cholerae) 		3 / 3 MET A  76
GLN A  29
ARG A  25
 None
 1.08A 6fnaB-3tgvA:
undetectable		 6fnaB-3tgvA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3tgv HEME-BINDING PROTEIN
HUTZ
(Vibrio
cholerae) 		3 / 3 MET A  76
GLN A  29
ARG A  25
 None
 1.06A 6fnbA-3tgvA:
undetectable		 6fnbA-3tgvA:
20.35