SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3th1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		4 / 6 LEU A  89
VAL A 156
VAL A 118
ASP A 120
 None
 1.14A 1dz4B-3th1A:
undetectable		 1dz4B-3th1A:
21.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		8 / 11 ASP A  51
ILE A  73
PRO A  76
TYR A 164
ARG A 185
HIS A 188
HIS A 190
CYH A 218
 DTD  A 301 (-4.1A)
DTD  A 301 (-4.9A)
DTD  A 301 (-4.5A)
DTD  A 301 ( 3.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
FE  A 300 (-3.3A)
DTD  A 301 ( 4.3A)
 0.87A 1s9aA-3th1A:
28.8		 1s9aA-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		9 / 11 ILE A  73
GLY A  75
PRO A  76
TYR A 130
TYR A 164
ARG A 185
HIS A 188
HIS A 190
CYH A 218
 DTD  A 301 (-4.9A)
DTD  A 301 (-3.5A)
DTD  A 301 (-4.5A)
FE  A 300 (-3.9A)
DTD  A 301 ( 3.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
FE  A 300 (-3.3A)
DTD  A 301 ( 4.3A)
 0.77A 1s9aA-3th1A:
28.8		 1s9aA-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		6 / 11 ILE A  73
PRO A  76
TYR A 130
ARG A 185
HIS A 188
CYH A 218
 DTD  A 301 (-4.9A)
DTD  A 301 (-4.5A)
FE  A 300 (-3.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
DTD  A 301 ( 4.3A)
 1.42A 1s9aA-3th1A:
28.8		 1s9aA-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		6 / 11 LEU A  48
ASP A  51
ILE A  73
TYR A  77
TYR A 164
CYH A 218
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.1A)
DTD  A 301 (-4.9A)
None
DTD  A 301 ( 3.9A)
DTD  A 301 ( 4.3A)
 1.34A 1s9aA-3th1A:
28.8		 1s9aA-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		7 / 11 LEU A  48
ASP A  51
ILE A  73
TYR A 164
ARG A 185
HIS A 188
CYH A 218
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.1A)
DTD  A 301 (-4.9A)
DTD  A 301 ( 3.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
DTD  A 301 ( 4.3A)
 0.82A 1s9aA-3th1A:
28.8		 1s9aA-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		7 / 11 LEU A  48
ILE A  73
GLY A  75
TYR A 164
ARG A 185
HIS A 188
CYH A 218
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.9A)
DTD  A 301 (-3.5A)
DTD  A 301 ( 3.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
DTD  A 301 ( 4.3A)
 0.96A 1s9aA-3th1A:
28.8		 1s9aA-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		9 / 12 ASP A  51
ILE A  73
TYR A 130
TYR A 164
ARG A 185
HIS A 188
HIS A 190
GLN A 204
CYH A 218
 DTD  A 301 (-4.1A)
DTD  A 301 (-4.9A)
FE  A 300 (-3.9A)
DTD  A 301 ( 3.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
FE  A 300 (-3.3A)
DTD  A 301 ( 4.5A)
DTD  A 301 ( 4.3A)
 0.66A 1s9aB-3th1A:
28.9		 1s9aB-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		7 / 12 ILE A  73
GLY A  75
PRO A  76
TYR A 130
HIS A 188
GLN A 204
CYH A 218
 DTD  A 301 (-4.9A)
DTD  A 301 (-3.5A)
DTD  A 301 (-4.5A)
FE  A 300 (-3.9A)
FE  A 300 (-3.5A)
DTD  A 301 ( 4.5A)
DTD  A 301 ( 4.3A)
 1.36A 1s9aB-3th1A:
28.9		 1s9aB-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		10 / 12 ILE A  73
GLY A  75
PRO A  76
TYR A 130
TYR A 164
ARG A 185
HIS A 188
HIS A 190
GLN A 204
CYH A 218
 DTD  A 301 (-4.9A)
DTD  A 301 (-3.5A)
DTD  A 301 (-4.5A)
FE  A 300 (-3.9A)
DTD  A 301 ( 3.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
FE  A 300 (-3.3A)
DTD  A 301 ( 4.5A)
DTD  A 301 ( 4.3A)
 0.62A 1s9aB-3th1A:
28.9		 1s9aB-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		6 / 12 ILE A  73
GLY A  75
PRO A  76
TYR A 164
HIS A 188
GLN A 204
 DTD  A 301 (-4.9A)
DTD  A 301 (-3.5A)
DTD  A 301 (-4.5A)
DTD  A 301 ( 3.9A)
FE  A 300 (-3.5A)
DTD  A 301 ( 4.5A)
 1.36A 1s9aB-3th1A:
28.9		 1s9aB-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		6 / 12 LEU A  48
ASP A  51
ILE A  73
HIS A 188
GLN A 204
CYH A 218
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.1A)
DTD  A 301 (-4.9A)
FE  A 300 (-3.5A)
DTD  A 301 ( 4.5A)
DTD  A 301 ( 4.3A)
 1.35A 1s9aB-3th1A:
28.9		 1s9aB-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		9 / 12 LEU A  48
ASP A  51
ILE A  73
TYR A 164
ARG A 185
HIS A 188
HIS A 190
GLN A 204
CYH A 218
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.1A)
DTD  A 301 (-4.9A)
DTD  A 301 ( 3.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
FE  A 300 (-3.3A)
DTD  A 301 ( 4.5A)
DTD  A 301 ( 4.3A)
 0.73A 1s9aB-3th1A:
28.9		 1s9aB-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		6 / 12 LEU A  48
ILE A  73
GLY A  75
HIS A 188
GLN A 204
CYH A 218
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.9A)
DTD  A 301 (-3.5A)
FE  A 300 (-3.5A)
DTD  A 301 ( 4.5A)
DTD  A 301 ( 4.3A)
 1.31A 1s9aB-3th1A:
28.9		 1s9aB-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		9 / 12 LEU A  48
ILE A  73
GLY A  75
TYR A 164
ARG A 185
HIS A 188
HIS A 190
GLN A 204
CYH A 218
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.9A)
DTD  A 301 (-3.5A)
DTD  A 301 ( 3.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
FE  A 300 (-3.3A)
DTD  A 301 ( 4.5A)
DTD  A 301 ( 4.3A)
 0.82A 1s9aB-3th1A:
28.9		 1s9aB-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		6 / 12 LEU A  48
ILE A  73
GLY A  75
TYR A 164
HIS A 188
GLN A 204
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.9A)
DTD  A 301 (-3.5A)
DTD  A 301 ( 3.9A)
FE  A 300 (-3.5A)
DTD  A 301 ( 4.5A)
 1.30A 1s9aB-3th1A:
28.9		 1s9aB-3th1A:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		5 / 12 LEU A  48
TYR A 164
ARG A 185
HIS A 188
CYH A 217
 DTD  A 301 ( 4.8A)
DTD  A 301 ( 3.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
None
 1.00A 1s9aB-3th1A:
28.9		 1s9aB-3th1A:
36.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		8 / 11 LEU A  48
ASP A  51
GLY A  75
PRO A  76
TYR A 130
TYR A 164
HIS A 188
HIS A 190
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.1A)
DTD  A 301 (-3.5A)
DTD  A 301 (-4.5A)
FE  A 300 (-3.9A)
DTD  A 301 ( 3.9A)
FE  A 300 (-3.5A)
FE  A 300 (-3.3A)
 1.02A 1tmxA-3th1A:
26.8		 1tmxA-3th1A:
28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		9 / 11 LEU A  48
GLY A  75
PRO A  76
TYR A 130
TYR A 164
ILE A 166
ARG A 185
HIS A 188
HIS A 190
 DTD  A 301 ( 4.8A)
DTD  A 301 (-3.5A)
DTD  A 301 (-4.5A)
FE  A 300 (-3.9A)
DTD  A 301 ( 3.9A)
DTD  A 301 ( 4.5A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
FE  A 300 (-3.3A)
 0.78A 1tmxA-3th1A:
26.8		 1tmxA-3th1A:
28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		6 / 11 LEU A  48
PRO A  76
TYR A 130
ILE A 166
ARG A 185
HIS A 188
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.5A)
FE  A 300 (-3.9A)
DTD  A 301 ( 4.5A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
 1.37A 1tmxA-3th1A:
26.8		 1tmxA-3th1A:
28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		8 / 12 LEU A  48
ASP A  51
GLY A  75
PRO A  76
TYR A 130
TYR A 164
HIS A 188
HIS A 190
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.1A)
DTD  A 301 (-3.5A)
DTD  A 301 (-4.5A)
FE  A 300 (-3.9A)
DTD  A 301 ( 3.9A)
FE  A 300 (-3.5A)
FE  A 300 (-3.3A)
 0.80A 1tmxB-3th1A:
26.8		 1tmxB-3th1A:
28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		7 / 12 LEU A  48
GLY A  75
PRO A  76
ILE A 166
ARG A 185
HIS A 190
HIS A 188
 DTD  A 301 ( 4.8A)
DTD  A 301 (-3.5A)
DTD  A 301 (-4.5A)
DTD  A 301 ( 4.5A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.3A)
FE  A 300 (-3.5A)
 1.49A 1tmxB-3th1A:
26.8		 1tmxB-3th1A:
28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		9 / 12 LEU A  48
GLY A  75
PRO A  76
TYR A 130
TYR A 164
ILE A 166
ARG A 185
HIS A 188
HIS A 190
 DTD  A 301 ( 4.8A)
DTD  A 301 (-3.5A)
DTD  A 301 (-4.5A)
FE  A 300 (-3.9A)
DTD  A 301 ( 3.9A)
DTD  A 301 ( 4.5A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
FE  A 300 (-3.3A)
 0.61A 1tmxB-3th1A:
26.8		 1tmxB-3th1A:
28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		5 / 12 LEU A  48
PRO A  76
TYR A 130
ILE A 166
HIS A 188
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.5A)
FE  A 300 (-3.9A)
DTD  A 301 ( 4.5A)
FE  A 300 (-3.5A)
 1.19A 1tmxB-3th1A:
26.8		 1tmxB-3th1A:
28.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		4 / 6 ARG A 246
GLY A 197
PHE A 198
PRO A 200
 None
 1.08A 2m2oB-3th1A:
undetectable		 2m2oB-3th1A:
11.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		7 / 12 ASP A  51
ILE A  73
PRO A  76
TYR A 130
TYR A 164
ARG A 185
HIS A 188
 DTD  A 301 (-4.1A)
DTD  A 301 (-4.9A)
DTD  A 301 (-4.5A)
FE  A 300 (-3.9A)
DTD  A 301 ( 3.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
 0.89A 3hgiA-3th1A:
29.5		 3hgiA-3th1A:
35.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		9 / 12 ILE A  73
GLY A  75
PRO A  76
TYR A  77
TYR A 130
TYR A 164
ARG A 185
HIS A 188
HIS A 190
 DTD  A 301 (-4.9A)
DTD  A 301 (-3.5A)
DTD  A 301 (-4.5A)
None
FE  A 300 (-3.9A)
DTD  A 301 ( 3.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
FE  A 300 (-3.3A)
 0.69A 3hgiA-3th1A:
29.5		 3hgiA-3th1A:
35.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		7 / 12 LEU A  48
ASP A  51
ILE A  73
PRO A  76
TYR A 164
ARG A 185
HIS A 188
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.1A)
DTD  A 301 (-4.9A)
DTD  A 301 (-4.5A)
DTD  A 301 ( 3.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
 0.97A 3hgiA-3th1A:
29.5		 3hgiA-3th1A:
35.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		5 / 12 LEU A  48
ASP A  51
VAL A  52
ILE A  73
ARG A 185
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.1A)
None
DTD  A 301 (-4.9A)
DTD  A 301 (-4.2A)
 0.73A 3hgiA-3th1A:
29.5		 3hgiA-3th1A:
35.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		5 / 12 LEU A  48
ASP A  51
VAL A  52
ILE A  73
TYR A 164
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.1A)
None
DTD  A 301 (-4.9A)
DTD  A 301 ( 3.9A)
 1.18A 3hgiA-3th1A:
29.5		 3hgiA-3th1A:
35.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		8 / 12 LEU A  48
ILE A  73
GLY A  75
PRO A  76
TYR A 164
ARG A 185
HIS A 188
HIS A 190
 DTD  A 301 ( 4.8A)
DTD  A 301 (-4.9A)
DTD  A 301 (-3.5A)
DTD  A 301 (-4.5A)
DTD  A 301 ( 3.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
FE  A 300 (-3.3A)
 0.90A 3hgiA-3th1A:
29.5		 3hgiA-3th1A:
35.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		5 / 12 LEU A  48
VAL A  52
ILE A  73
ARG A 185
HIS A 188
 DTD  A 301 ( 4.8A)
None
DTD  A 301 (-4.9A)
DTD  A 301 (-4.2A)
FE  A 300 (-3.5A)
 1.27A 3hgiA-3th1A:
29.5		 3hgiA-3th1A:
35.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		5 / 12 LEU A  48
VAL A  52
ILE A  73
TYR A 164
HIS A 188
 DTD  A 301 ( 4.8A)
None
DTD  A 301 (-4.9A)
DTD  A 301 ( 3.9A)
FE  A 300 (-3.5A)
 1.17A 3hgiA-3th1A:
29.5		 3hgiA-3th1A:
35.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		4 / 5 THR A 183
ILE A 166
GLU A  45
PHE A  53
 None
DTD  A 301 ( 4.5A)
None
3PH  A 302 ( 4.9A)
 1.12A 4ac9C-3th1A:
undetectable		 4ac9C-3th1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		4 / 5 THR A 183
ILE A 166
GLU A  45
PHE A  53
 None
DTD  A 301 ( 4.5A)
None
3PH  A 302 ( 4.9A)
 1.14A 4acaC-3th1A:
undetectable		 4acaC-3th1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		4 / 5 THR A 183
ILE A 166
GLU A  45
PHE A  53
 None
DTD  A 301 ( 4.5A)
None
3PH  A 302 ( 4.9A)
 1.21A 4acbC-3th1A:
undetectable		 4acbC-3th1A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		4 / 6 GLY A 128
SER A 124
VAL A 162
HIS A  97
 None
 1.15A 5ewuA-3th1A:
undetectable		 5ewuA-3th1A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		3 / 3 THR A  94
PRO A 138
ARG A 143
 None
 0.79A 5nd7B-3th1A:
undetectable		 5nd7B-3th1A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 3th1 CHLOROCATECHOL
1,2-DIOXYGENASE
(Pseudomonas
putida) 		5 / 12 VAL A 121
PHE A 191
ILE A 119
LEU A 240
VAL A 189
 None
 0.86A 5uvmB-3th1A:
undetectable		 5uvmB-3th1A:
21.22