SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ti8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.38A 1a4gA-3ti8A:
53.9		 1a4gA-3ti8A:
36.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_A_ZMRA466_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.12A 1a4gA-3ti8A:
53.9		 1a4gA-3ti8A:
36.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.42A 1a4gB-3ti8A:
54.0		 1a4gB-3ti8A:
36.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ASP A 151
ARG A 152
ILE A 222
 LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
None
 0.21A 1a4gB-3ti8A:
54.0		 1a4gB-3ti8A:
36.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F9G_A_ASCA950_0
(HYALURONATE LYASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 ARG A 152
ASN A 294
ARG A 371
ARG A 118
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-3.0A)
 1.45A 1f9gA-3ti8A:
undetectable		 1f9gA-3ti8A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 ARG A 300
VAL A 290
ASN A 299
ASP A 324
 None
None
None
CA  A 601 (-3.3A)
 1.32A 1hwiC-3ti8A:
undetectable		 1hwiC-3ti8A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 ARG A 300
VAL A 290
ASN A 299
ASP A 324
 None
None
None
CA  A 601 (-3.3A)
 1.32A 1hwiD-3ti8A:
undetectable		 1hwiD-3ti8A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 1k2rA-3ti8A:
undetectable
1k2rB-3ti8A:
undetectable		 1k2rA-3ti8A:
22.15
1k2rB-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 1k2rA-3ti8A:
undetectable
1k2rB-3ti8A:
undetectable		 1k2rA-3ti8A:
22.15
1k2rB-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 1k2sA-3ti8A:
undetectable
1k2sB-3ti8A:
undetectable		 1k2sA-3ti8A:
22.15
1k2sB-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 1k2sA-3ti8A:
undetectable
1k2sB-3ti8A:
undetectable		 1k2sA-3ti8A:
22.15
1k2sB-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 1k2tA-3ti8A:
undetectable
1k2tB-3ti8A:
undetectable		 1k2tA-3ti8A:
22.15
1k2tB-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 1k2tA-3ti8A:
undetectable
1k2tB-3ti8A:
undetectable		 1k2tA-3ti8A:
22.15
1k2tB-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 1k2uA-3ti8A:
undetectable
1k2uB-3ti8A:
undetectable		 1k2uA-3ti8A:
22.15
1k2uB-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.44A 1k2uA-3ti8A:
undetectable
1k2uB-3ti8A:
undetectable		 1k2uA-3ti8A:
22.15
1k2uB-3ti8A:
22.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7F_A_BCZA801_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
TRP A 178
ILE A 222
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
None
None
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.8A)
 0.45A 1l7fA-3ti8A:
65.0		 1l7fA-3ti8A:
43.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
ARG A 152
ARG A 371
 LNV  A 901 (-3.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
 0.13A 1l7fA-3ti8A:
65.0		 1l7fA-3ti8A:
43.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7G_A_BCZA801_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 LEU A 134
ASP A 151
ARG A 152
ARG A 156
TRP A 178
ILE A 222
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.8A)
 0.45A 1l7gA-3ti8A:
65.0		 1l7gA-3ti8A:
43.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7H_A_BCZA801_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
TRP A 178
ILE A 222
ARG A 224
GLU A 227
GLU A 276
GLU A 277
TYR A 406
 LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
None
None
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-4.8A)
 0.48A 1l7hA-3ti8A:
64.9		 1l7hA-3ti8A:
43.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
ARG A 152
ARG A 371
 LNV  A 901 (-3.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
 0.12A 1l7hA-3ti8A:
64.9		 1l7hA-3ti8A:
43.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 1lzxA-3ti8A:
undetectable
1lzxB-3ti8A:
undetectable		 1lzxA-3ti8A:
22.15
1lzxB-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 1lzxA-3ti8A:
undetectable
1lzxB-3ti8A:
undetectable		 1lzxA-3ti8A:
22.15
1lzxB-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 1lzzA-3ti8A:
undetectable
1lzzB-3ti8A:
undetectable		 1lzzA-3ti8A:
22.15
1lzzB-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 1lzzA-3ti8A:
undetectable
1lzzB-3ti8A:
undetectable		 1lzzA-3ti8A:
22.15
1lzzB-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 1m00A-3ti8A:
undetectable
1m00B-3ti8A:
undetectable		 1m00A-3ti8A:
22.15
1m00B-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.44A 1m00A-3ti8A:
undetectable
1m00B-3ti8A:
undetectable		 1m00A-3ti8A:
22.15
1m00B-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 1mmvA-3ti8A:
undetectable
1mmvB-3ti8A:
undetectable		 1mmvA-3ti8A:
22.15
1mmvB-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 1mmvA-3ti8A:
undetectable
1mmvB-3ti8A:
undetectable		 1mmvA-3ti8A:
22.15
1mmvB-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 1mmwA-3ti8A:
undetectable
1mmwB-3ti8A:
undetectable		 1mmwA-3ti8A:
22.15
1mmwB-3ti8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 1mmwA-3ti8A:
undetectable
1mmwB-3ti8A:
undetectable		 1mmwA-3ti8A:
22.15
1mmwB-3ti8A:
22.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ARG A 152
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.34A 1nncA-3ti8A:
64.3		 1nncA-3ti8A:
43.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		6 / 12 ARG A 224
ALA A 246
GLU A 276
GLU A 277
ARG A 118
TYR A 406
 LNV  A 901 (-4.1A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.0A)
LNV  A 901 (-4.8A)
 1.49A 1nncA-3ti8A:
64.3		 1nncA-3ti8A:
43.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NNC_A_ZMRA479_2
(NEURAMINIDASE N9)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ASP A 151
ARG A 156
TRP A 178
ILE A 222
 LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
None
None
 0.14A 1nncA-3ti8A:
64.3		 1nncA-3ti8A:
43.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 1om4A-3ti8A:
undetectable
1om4B-3ti8A:
undetectable		 1om4A-3ti8A:
22.64
1om4B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.44A 1om4A-3ti8A:
undetectable
1om4B-3ti8A:
undetectable		 1om4A-3ti8A:
22.64
1om4B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.33A 1om5A-3ti8A:
undetectable
1om5B-3ti8A:
undetectable		 1om5A-3ti8A:
22.37
1om5B-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 1om5A-3ti8A:
undetectable
1om5B-3ti8A:
undetectable		 1om5A-3ti8A:
22.37
1om5B-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 1p6hA-3ti8A:
undetectable
1p6hB-3ti8A:
undetectable		 1p6hA-3ti8A:
22.37
1p6hB-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 1p6hA-3ti8A:
undetectable
1p6hB-3ti8A:
undetectable		 1p6hA-3ti8A:
22.37
1p6hB-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 1p6iA-3ti8A:
undetectable
1p6iB-3ti8A:
undetectable		 1p6iA-3ti8A:
22.37
1p6iB-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 1p6iA-3ti8A:
undetectable
1p6iB-3ti8A:
undetectable		 1p6iA-3ti8A:
22.37
1p6iB-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 1p6jA-3ti8A:
undetectable
1p6jB-3ti8A:
undetectable		 1p6jA-3ti8A:
22.37
1p6jB-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 1p6jA-3ti8A:
undetectable
1p6jB-3ti8A:
undetectable		 1p6jA-3ti8A:
22.37
1p6jB-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 1p6kA-3ti8A:
undetectable
1p6kB-3ti8A:
undetectable		 1p6kA-3ti8A:
22.37
1p6kB-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 1p6kA-3ti8A:
undetectable
1p6kB-3ti8A:
undetectable		 1p6kA-3ti8A:
22.37
1p6kB-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.46A 1rs6A-3ti8A:
undetectable
1rs6B-3ti8A:
undetectable		 1rs6A-3ti8A:
22.37
1rs6B-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 1rs6A-3ti8A:
undetectable
1rs6B-3ti8A:
undetectable		 1rs6A-3ti8A:
22.37
1rs6B-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 1rs7A-3ti8A:
undetectable
1rs7B-3ti8A:
undetectable		 1rs7A-3ti8A:
22.37
1rs7B-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.45A 1rs7A-3ti8A:
undetectable
1rs7B-3ti8A:
undetectable		 1rs7A-3ti8A:
22.37
1rs7B-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 1zvlA-3ti8A:
undetectable
1zvlB-3ti8A:
undetectable		 1zvlA-3ti8A:
22.37
1zvlB-3ti8A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 1zzqA-3ti8A:
undetectable
1zzqB-3ti8A:
undetectable		 1zzqA-3ti8A:
22.42
1zzqB-3ti8A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 1zzqA-3ti8A:
undetectable
1zzqB-3ti8A:
undetectable		 1zzqA-3ti8A:
22.42
1zzqB-3ti8A:
22.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.22A 2cmlA-3ti8A:
64.9		 2cmlA-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 227
ALA A 246
ARG A 292
ASN A 294
TYR A 406
 LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.8A)
 1.14A 2cmlA-3ti8A:
64.9		 2cmlA-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1477_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.22A 2cmlA-3ti8A:
64.9		 2cmlA-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 SER A 367
SER A 372
ASN A 400
TRP A 403
 None
 0.14A 2cmlA-3ti8A:
64.9		 2cmlA-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.21A 2cmlB-3ti8A:
64.8		 2cmlB-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_B_ZMRB2477_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.24A 2cmlB-3ti8A:
64.8		 2cmlB-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 8 SER A 367
SER A 370
SER A 372
ASN A 400
TRP A 403
 None
 0.52A 2cmlB-3ti8A:
64.8		 2cmlB-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.23A 2cmlC-3ti8A:
64.7		 2cmlC-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 227
ALA A 246
ARG A 292
ASN A 294
TYR A 406
 LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.8A)
 1.18A 2cmlC-3ti8A:
64.7		 2cmlC-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3477_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.31A 2cmlC-3ti8A:
64.7		 2cmlC-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 SER A 367
SER A 372
ASN A 400
TRP A 403
 None
 0.21A 2cmlC-3ti8A:
64.7		 2cmlC-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.24A 2cmlD-3ti8A:
64.8		 2cmlD-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_D_ZMRD4477_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.26A 2cmlD-3ti8A:
64.8		 2cmlD-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 SER A 367
SER A 370
ASN A 400
TRP A 403
 None
 0.70A 2cmlD-3ti8A:
64.8		 2cmlD-3ti8A:
45.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 SER A 367
SER A 372
ASN A 400
TRP A 403
 None
 0.20A 2cmlD-3ti8A:
64.8		 2cmlD-3ti8A:
45.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 118
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.43A 2f0zA-3ti8A:
7.6		 2f0zA-3ti8A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 156
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 901 (-4.0A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 1.09A 2f0zA-3ti8A:
7.6		 2f0zA-3ti8A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F10_A_BCZA382_0
(SIALIDASE 2)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 118
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.45A 2f10A-3ti8A:
11.0		 2f10A-3ti8A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 2g6hA-3ti8A:
undetectable
2g6hB-3ti8A:
undetectable		 2g6hA-3ti8A:
22.42
2g6hB-3ti8A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.46A 2g6hA-3ti8A:
undetectable
2g6hB-3ti8A:
undetectable		 2g6hA-3ti8A:
22.42
2g6hB-3ti8A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 2g6kA-3ti8A:
undetectable
2g6kB-3ti8A:
undetectable		 2g6kA-3ti8A:
22.42
2g6kB-3ti8A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.45A 2g6kA-3ti8A:
undetectable
2g6kB-3ti8A:
undetectable		 2g6kA-3ti8A:
22.42
2g6kB-3ti8A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 2g6mA-3ti8A:
undetectable
2g6mB-3ti8A:
undetectable		 2g6mA-3ti8A:
22.42
2g6mB-3ti8A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.44A 2g6mA-3ti8A:
undetectable
2g6mB-3ti8A:
undetectable		 2g6mA-3ti8A:
22.42
2g6mB-3ti8A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_B_017B203_1
(HIV-1 PROTEASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 GLU A 128
PRO A  82
LYS A 188
GLY A 125
 None
 1.29A 2hs1B-3ti8A:
undetectable		 2hs1B-3ti8A:
14.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ARG A 152
ARG A 156
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 347
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 ( 4.7A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.52A 2htqA-3ti8A:
71.8		 2htqA-3ti8A:
69.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTQ_A_ZMRA472_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ASP A 151
TRP A 178
ILE A 222
ARG A 224
 LNV  A 901 (-3.4A)
None
None
LNV  A 901 (-4.1A)
 0.30A 2htqA-3ti8A:
71.8		 2htqA-3ti8A:
69.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTU_A_BCZA801_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
TRP A 178
SER A 179
ILE A 222
ARG A 224
GLU A 276
ARG A 292
TYR A 347
TYR A 406
 LNV  A 901 (-3.6A)
None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
LNV  A 901 ( 4.6A)
None
LNV  A 901 (-4.1A)
LNV  A 901 (-2.9A)
LNV  A 901 (-2.8A)
LNV  A 901 ( 4.7A)
LNV  A 901 (-4.8A)
 0.52A 2htuA-3ti8A:
73.3		 2htuA-3ti8A:
69.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTU_A_BCZA801_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 118
ASP A 151
GLU A 227
ARG A 371
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
 0.29A 2htuA-3ti8A:
73.3		 2htuA-3ti8A:
69.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 2hx3A-3ti8A:
undetectable
2hx3B-3ti8A:
undetectable		 2hx3A-3ti8A:
22.64
2hx3B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 2hx3A-3ti8A:
undetectable
2hx3B-3ti8A:
undetectable		 2hx3A-3ti8A:
22.64
2hx3B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 2hx4A-3ti8A:
undetectable
2hx4B-3ti8A:
undetectable		 2hx4A-3ti8A:
22.64
2hx4B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 2hx4A-3ti8A:
undetectable
2hx4B-3ti8A:
undetectable		 2hx4A-3ti8A:
22.64
2hx4B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 3b3mA-3ti8A:
undetectable
3b3mB-3ti8A:
undetectable		 3b3mA-3ti8A:
22.64
3b3mB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 3b3mA-3ti8A:
undetectable
3b3mB-3ti8A:
undetectable		 3b3mA-3ti8A:
22.64
3b3mB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 3b3nA-3ti8A:
undetectable
3b3nB-3ti8A:
undetectable		 3b3nA-3ti8A:
22.64
3b3nB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 3b3nA-3ti8A:
undetectable
3b3nB-3ti8A:
undetectable		 3b3nA-3ti8A:
22.64
3b3nB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 3b3oA-3ti8A:
undetectable
3b3oB-3ti8A:
undetectable		 3b3oA-3ti8A:
22.64
3b3oB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 3b3oA-3ti8A:
undetectable
3b3oB-3ti8A:
undetectable		 3b3oA-3ti8A:
22.64
3b3oB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.37A 3b3pA-3ti8A:
undetectable
3b3pB-3ti8A:
undetectable		 3b3pA-3ti8A:
22.64
3b3pB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 3b3pA-3ti8A:
undetectable
3b3pB-3ti8A:
undetectable		 3b3pA-3ti8A:
22.64
3b3pB-3ti8A:
22.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.10A 3b7eA-3ti8A:
69.9		 3b7eA-3ti8A:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_A_ZMRA1001_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.06A 3b7eA-3ti8A:
69.9		 3b7eA-3ti8A:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.11A 3b7eB-3ti8A:
69.7		 3b7eB-3ti8A:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_B_ZMRB1002_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.04A 3b7eB-3ti8A:
69.7		 3b7eB-3ti8A:
58.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 152
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
TYR A 347
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-4.0A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 ( 4.7A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.33A 3ckzA-3ti8A:
69.9		 3ckzA-3ti8A:
57.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 6 ASP A 151
ARG A 156
TRP A 178
ILE A 222
ARG A 224
 LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
None
None
LNV  A 901 (-4.1A)
 0.68A 3ckzA-3ti8A:
69.9		 3ckzA-3ti8A:
57.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_1
(CYTOCHROME P450 2R1)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 THR A 148
ALA A 157
THR A 131
VAL A 161
MET A 159
 None
 0.97A 3czhA-3ti8A:
undetectable		 3czhA-3ti8A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 THR A 148
ALA A 157
THR A 131
VAL A 161
MET A 159
 None
 0.99A 3czhB-3ti8A:
undetectable		 3czhB-3ti8A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 3fc5A-3ti8A:
undetectable
3fc5B-3ti8A:
undetectable		 3fc5A-3ti8A:
22.64
3fc5B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.44A 3fc5A-3ti8A:
undetectable
3fc5B-3ti8A:
undetectable		 3fc5A-3ti8A:
22.64
3fc5B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 GLU A 227
GLU A 277
TRP A 423
 LNV  A 901 (-3.4A)
LNV  A 901 ( 3.8A)
None
 0.91A 3hrdA-3ti8A:
undetectable
3hrdE-3ti8A:
undetectable
3hrdF-3ti8A:
undetectable		 3hrdA-3ti8A:
20.54
3hrdE-3ti8A:
20.54
3hrdF-3ti8A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 3hsnA-3ti8A:
undetectable
3hsnB-3ti8A:
undetectable		 3hsnA-3ti8A:
22.64
3hsnB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 3hsnA-3ti8A:
undetectable
3hsnB-3ti8A:
undetectable		 3hsnA-3ti8A:
22.64
3hsnB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.45A 3hsoA-3ti8A:
undetectable
3hsoB-3ti8A:
undetectable		 3hsoA-3ti8A:
22.64
3hsoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 3hsoA-3ti8A:
undetectable
3hsoB-3ti8A:
undetectable		 3hsoA-3ti8A:
22.64
3hsoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 3hspA-3ti8A:
undetectable
3hspB-3ti8A:
undetectable		 3hspA-3ti8A:
22.64
3hspB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 3hspA-3ti8A:
undetectable
3hspB-3ti8A:
undetectable		 3hspA-3ti8A:
22.64
3hspB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 3jt3A-3ti8A:
undetectable
3jt3B-3ti8A:
undetectable		 3jt3A-3ti8A:
22.64
3jt3B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 3jt3A-3ti8A:
undetectable
3jt3B-3ti8A:
undetectable		 3jt3A-3ti8A:
22.64
3jt3B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 3jt4A-3ti8A:
undetectable
3jt4B-3ti8A:
undetectable		 3jt4A-3ti8A:
22.64
3jt4B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 3jt4A-3ti8A:
undetectable
3jt4B-3ti8A:
undetectable		 3jt4A-3ti8A:
22.64
3jt4B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 3jt5A-3ti8A:
undetectable
3jt5B-3ti8A:
undetectable		 3jt5A-3ti8A:
22.64
3jt5B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.44A 3jt5A-3ti8A:
undetectable
3jt5B-3ti8A:
undetectable		 3jt5A-3ti8A:
22.64
3jt5B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 3jt6A-3ti8A:
undetectable
3jt6B-3ti8A:
undetectable		 3jt6A-3ti8A:
22.64
3jt6B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 3jt6A-3ti8A:
undetectable
3jt6B-3ti8A:
undetectable		 3jt6A-3ti8A:
22.64
3jt6B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 3jt7A-3ti8A:
undetectable
3jt7B-3ti8A:
undetectable		 3jt7A-3ti8A:
22.64
3jt7B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 3jt7A-3ti8A:
undetectable
3jt7B-3ti8A:
undetectable		 3jt7A-3ti8A:
22.64
3jt7B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 3jt8A-3ti8A:
undetectable
3jt8B-3ti8A:
undetectable		 3jt8A-3ti8A:
22.64
3jt8B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 3jt8A-3ti8A:
undetectable
3jt8B-3ti8A:
undetectable		 3jt8A-3ti8A:
22.64
3jt8B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 3jt9A-3ti8A:
undetectable
3jt9B-3ti8A:
undetectable		 3jt9A-3ti8A:
22.64
3jt9B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 3jt9A-3ti8A:
undetectable
3jt9B-3ti8A:
undetectable		 3jt9A-3ti8A:
22.64
3jt9B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 3jtaA-3ti8A:
undetectable
3jtaB-3ti8A:
undetectable		 3jtaA-3ti8A:
22.64
3jtaB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 3jtaA-3ti8A:
undetectable
3jtaB-3ti8A:
undetectable		 3jtaA-3ti8A:
22.64
3jtaB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 3jwsA-3ti8A:
undetectable
3jwsB-3ti8A:
undetectable		 3jwsA-3ti8A:
22.79
3jwsB-3ti8A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 3jwsA-3ti8A:
undetectable
3jwsB-3ti8A:
undetectable		 3jwsA-3ti8A:
22.79
3jwsB-3ti8A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 3jwtA-3ti8A:
undetectable
3jwtB-3ti8A:
undetectable		 3jwtA-3ti8A:
22.79
3jwtB-3ti8A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 3jwtA-3ti8A:
undetectable
3jwtB-3ti8A:
undetectable		 3jwtA-3ti8A:
22.79
3jwtB-3ti8A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 3jwuA-3ti8A:
undetectable
3jwuB-3ti8A:
undetectable		 3jwuA-3ti8A:
22.79
3jwuB-3ti8A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 3jwuA-3ti8A:
undetectable
3jwuB-3ti8A:
undetectable		 3jwuA-3ti8A:
22.79
3jwuB-3ti8A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 3jwvA-3ti8A:
undetectable
3jwvB-3ti8A:
undetectable		 3jwvA-3ti8A:
22.79
3jwvB-3ti8A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 3jwvA-3ti8A:
undetectable
3jwvB-3ti8A:
undetectable		 3jwvA-3ti8A:
22.79
3jwvB-3ti8A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 3jx0A-3ti8A:
undetectable
3jx0B-3ti8A:
undetectable		 3jx0A-3ti8A:
22.64
3jx0B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 3jx0A-3ti8A:
undetectable
3jx0B-3ti8A:
undetectable		 3jx0A-3ti8A:
22.64
3jx0B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.35A 3jx1A-3ti8A:
undetectable
3jx1B-3ti8A:
undetectable		 3jx1A-3ti8A:
22.64
3jx1B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 3jx1A-3ti8A:
undetectable
3jx1B-3ti8A:
undetectable		 3jx1A-3ti8A:
22.64
3jx1B-3ti8A:
22.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_A_BCZA468_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 156
TRP A 178
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-4.0A)
None
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.8A)
 0.43A 3k37A-3ti8A:
53.9		 3k37A-3ti8A:
35.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ASP A 151
ARG A 152
ARG A 371
 LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
 0.16A 3k37A-3ti8A:
53.9		 3k37A-3ti8A:
35.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 156
TRP A 178
ARG A 224
GLU A 227
ALA A 246
GLU A 277
ARG A 292
ARG A 371
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
None
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-2.9A)
 0.34A 3k37B-3ti8A:
53.9		 3k37B-3ti8A:
35.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
GLU A 276
TYR A 406
 LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.23A 3k37B-3ti8A:
53.9		 3k37B-3ti8A:
35.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.8A)
 0.55A 3k39A-3ti8A:
53.2		 3k39A-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 277
ARG A 292
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.8A)
 0.47A 3k39B-3ti8A:
53.2		 3k39B-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
 0.54A 3k39C-3ti8A:
53.3		 3k39C-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
 1.48A 3k39C-3ti8A:
53.3		 3k39C-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
 LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-2.9A)
 0.55A 3k39D-3ti8A:
53.3		 3k39D-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.8A)
 0.54A 3k39E-3ti8A:
53.3		 3k39E-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.8A)
 0.53A 3k39F-3ti8A:
53.4		 3k39F-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.8A)
 0.54A 3k39G-3ti8A:
53.4		 3k39G-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.8A)
 0.54A 3k39H-3ti8A:
53.3		 3k39H-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
 0.54A 3k39I-3ti8A:
53.2		 3k39I-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
 1.47A 3k39I-3ti8A:
53.2		 3k39I-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
 0.55A 3k39J-3ti8A:
53.3		 3k39J-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
 1.48A 3k39J-3ti8A:
53.3		 3k39J-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
 0.55A 3k39K-3ti8A:
53.3		 3k39K-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
 1.48A 3k39K-3ti8A:
53.3		 3k39K-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
 0.54A 3k39L-3ti8A:
53.3		 3k39L-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
 1.49A 3k39L-3ti8A:
53.3		 3k39L-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.8A)
 0.54A 3k39M-3ti8A:
53.4		 3k39M-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 901 (-3.6A)
None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.53A 3k39N-3ti8A:
53.3		 3k39N-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.55A 3k39O-3ti8A:
53.4		 3k39O-3ti8A:
35.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 901 (-3.6A)
None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.54A 3k39P-3ti8A:
53.4		 3k39P-3ti8A:
35.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 3n2rA-3ti8A:
undetectable
3n2rB-3ti8A:
undetectable		 3n2rA-3ti8A:
22.64
3n2rB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 3n2rA-3ti8A:
undetectable
3n2rB-3ti8A:
undetectable		 3n2rA-3ti8A:
22.64
3n2rB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.34A 3n5vA-3ti8A:
undetectable
3n5vB-3ti8A:
undetectable		 3n5vA-3ti8A:
22.64
3n5vB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 3n5vA-3ti8A:
undetectable
3n5vB-3ti8A:
undetectable		 3n5vA-3ti8A:
22.64
3n5vB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 3n5yA-3ti8A:
undetectable
3n5yB-3ti8A:
undetectable		 3n5yA-3ti8A:
22.64
3n5yB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 3n5yA-3ti8A:
undetectable
3n5yB-3ti8A:
undetectable		 3n5yA-3ti8A:
22.64
3n5yB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 3n5zA-3ti8A:
undetectable
3n5zB-3ti8A:
undetectable		 3n5zA-3ti8A:
22.64
3n5zB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 3n5zA-3ti8A:
undetectable
3n5zB-3ti8A:
undetectable		 3n5zA-3ti8A:
22.64
3n5zB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 3n61A-3ti8A:
undetectable
3n61B-3ti8A:
undetectable		 3n61A-3ti8A:
22.64
3n61B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.29A 3n65A-3ti8A:
undetectable
3n65B-3ti8A:
undetectable		 3n65A-3ti8A:
22.25
3n65B-3ti8A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 3nlkA-3ti8A:
undetectable
3nlkB-3ti8A:
undetectable		 3nlkA-3ti8A:
22.79
3nlkB-3ti8A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 3nlkA-3ti8A:
undetectable
3nlkB-3ti8A:
undetectable		 3nlkA-3ti8A:
22.79
3nlkB-3ti8A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.35A 3nlmA-3ti8A:
undetectable
3nlmB-3ti8A:
undetectable		 3nlmA-3ti8A:
22.64
3nlmB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 3nlmA-3ti8A:
undetectable
3nlmB-3ti8A:
undetectable		 3nlmA-3ti8A:
22.64
3nlmB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 3nlnA-3ti8A:
undetectable
3nlnB-3ti8A:
undetectable		 3nlnA-3ti8A:
22.79
3nlnB-3ti8A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 3nlnA-3ti8A:
undetectable
3nlnB-3ti8A:
undetectable		 3nlnA-3ti8A:
22.79
3nlnB-3ti8A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 3nloA-3ti8A:
undetectable
3nloB-3ti8A:
undetectable		 3nloA-3ti8A:
22.79
3nloB-3ti8A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 3nlvA-3ti8A:
undetectable
3nlvB-3ti8A:
undetectable		 3nlvA-3ti8A:
22.64
3nlvB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 3nlvA-3ti8A:
undetectable
3nlvB-3ti8A:
undetectable		 3nlvA-3ti8A:
22.64
3nlvB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.37A 3nlwA-3ti8A:
undetectable
3nlwB-3ti8A:
undetectable		 3nlwA-3ti8A:
22.64
3nlwB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 3nlwA-3ti8A:
undetectable
3nlwB-3ti8A:
undetectable		 3nlwA-3ti8A:
22.64
3nlwB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.37A 3nlxA-3ti8A:
undetectable
3nlxB-3ti8A:
undetectable		 3nlxA-3ti8A:
22.64
3nlxB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.34A 3nlxA-3ti8A:
undetectable
3nlxB-3ti8A:
undetectable		 3nlxA-3ti8A:
22.64
3nlxB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.35A 3nlyA-3ti8A:
undetectable
3nlyB-3ti8A:
undetectable		 3nlyA-3ti8A:
22.64
3nlyB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.33A 3nlyA-3ti8A:
undetectable
3nlyB-3ti8A:
undetectable		 3nlyA-3ti8A:
22.64
3nlyB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.35A 3nlzA-3ti8A:
undetectable
3nlzB-3ti8A:
undetectable		 3nlzA-3ti8A:
22.64
3nlzB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 3nlzA-3ti8A:
undetectable
3nlzB-3ti8A:
undetectable		 3nlzA-3ti8A:
22.64
3nlzB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.37A 3nm0A-3ti8A:
undetectable
3nm0B-3ti8A:
undetectable		 3nm0A-3ti8A:
22.64
3nm0B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 3nm0A-3ti8A:
undetectable
3nm0B-3ti8A:
undetectable		 3nm0A-3ti8A:
22.64
3nm0B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.34A 3nnyA-3ti8A:
undetectable
3nnyB-3ti8A:
undetectable		 3nnyA-3ti8A:
22.64
3nnyB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 3nnyA-3ti8A:
undetectable
3nnyB-3ti8A:
undetectable		 3nnyA-3ti8A:
22.64
3nnyB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.37A 3nnzA-3ti8A:
undetectable
3nnzB-3ti8A:
undetectable		 3nnzA-3ti8A:
22.64
3nnzB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 3nnzA-3ti8A:
undetectable
3nnzB-3ti8A:
undetectable		 3nnzA-3ti8A:
22.64
3nnzB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 ILE A 412
MET A 233
ASN A 236
PHE A 410
 None
 0.99A 3octA-3ti8A:
undetectable		 3octA-3ti8A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.35A 3pneA-3ti8A:
undetectable
3pneB-3ti8A:
undetectable		 3pneA-3ti8A:
22.64
3pneB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 3pneA-3ti8A:
undetectable
3pneB-3ti8A:
undetectable		 3pneA-3ti8A:
22.64
3pneB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.37A 3pnfA-3ti8A:
undetectable
3pnfB-3ti8A:
undetectable		 3pnfA-3ti8A:
22.64
3pnfB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 3pnfA-3ti8A:
undetectable
3pnfB-3ti8A:
undetectable		 3pnfA-3ti8A:
22.64
3pnfB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.35A 3pngA-3ti8A:
undetectable
3pngB-3ti8A:
undetectable		 3pngA-3ti8A:
22.64
3pngB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.33A 3pngA-3ti8A:
undetectable
3pngB-3ti8A:
undetectable		 3pngA-3ti8A:
22.64
3pngB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 3q99A-3ti8A:
undetectable
3q99B-3ti8A:
undetectable		 3q99A-3ti8A:
22.64
3q99B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.44A 3q99A-3ti8A:
undetectable
3q99B-3ti8A:
undetectable		 3q99A-3ti8A:
22.64
3q99B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 3q9aA-3ti8A:
undetectable
3q9aB-3ti8A:
undetectable		 3q9aA-3ti8A:
22.64
3q9aB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 3q9aA-3ti8A:
undetectable
3q9aB-3ti8A:
undetectable		 3q9aA-3ti8A:
22.64
3q9aB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.37A 3rqjA-3ti8A:
undetectable
3rqjB-3ti8A:
undetectable		 3rqjA-3ti8A:
22.64
3rqjB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 3rqjA-3ti8A:
undetectable
3rqjB-3ti8A:
undetectable		 3rqjA-3ti8A:
22.64
3rqjB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.33A 3rqkA-3ti8A:
undetectable
3rqkB-3ti8A:
undetectable		 3rqkA-3ti8A:
22.64
3rqkB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.34A 3rqkA-3ti8A:
undetectable
3rqkB-3ti8A:
undetectable		 3rqkA-3ti8A:
22.64
3rqkB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.35A 3rqlA-3ti8A:
undetectable
3rqlB-3ti8A:
undetectable		 3rqlA-3ti8A:
22.64
3rqlB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.35A 3rqlA-3ti8A:
undetectable
3rqlB-3ti8A:
undetectable		 3rqlA-3ti8A:
22.64
3rqlB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.36A 3rqmA-3ti8A:
undetectable
3rqmB-3ti8A:
undetectable		 3rqmA-3ti8A:
22.64
3rqmB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 3rqmA-3ti8A:
undetectable
3rqmB-3ti8A:
undetectable		 3rqmA-3ti8A:
22.64
3rqmB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.35A 3rqnA-3ti8A:
undetectable
3rqnB-3ti8A:
undetectable		 3rqnA-3ti8A:
22.64
3rqnB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 3rqnA-3ti8A:
undetectable
3rqnB-3ti8A:
undetectable		 3rqnA-3ti8A:
22.64
3rqnB-3ti8A:
22.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
TYR A 347
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 ( 4.7A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.05A 3sanA-3ti8A:
79.7		 3sanA-3ti8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_A_ZMRA901_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 ASP A 151
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.04A 3sanA-3ti8A:
79.7		 3sanA-3ti8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
TYR A 347
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 ( 4.7A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.10A 3sanB-3ti8A:
79.3		 3sanB-3ti8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_B_ZMRB901_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 ASP A 151
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.03A 3sanB-3ti8A:
79.3		 3sanB-3ti8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 PRO A 166
ILE A 117
SER A 440
ILE A 106
 None
 0.86A 3sfeB-3ti8A:
undetectable
3sfeC-3ti8A:
undetectable		 3sfeB-3ti8A:
21.33
3sfeC-3ti8A:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.31A 3svpA-3ti8A:
undetectable
3svpB-3ti8A:
undetectable		 3svpA-3ti8A:
22.64
3svpB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.34A 3svpA-3ti8A:
undetectable
3svpB-3ti8A:
undetectable		 3svpA-3ti8A:
22.64
3svpB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.36A 3svqA-3ti8A:
undetectable
3svqB-3ti8A:
undetectable		 3svqA-3ti8A:
22.64
3svqB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.32A 3svqA-3ti8A:
undetectable
3svqB-3ti8A:
undetectable		 3svqA-3ti8A:
22.64
3svqB-3ti8A:
22.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.11A 3ti5A-3ti8A:
70.5		 3ti5A-3ti8A:
57.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_A_ZMRA1002_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.08A 3ti5A-3ti8A:
70.5		 3ti5A-3ti8A:
57.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.12A 3ti5B-3ti8A:
70.4		 3ti5B-3ti8A:
57.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_B_ZMRB1002_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.08A 3ti5B-3ti8A:
70.4		 3ti5B-3ti8A:
57.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
TRP A 178
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.18A 3ticA-3ti8A:
65.2		 3ticA-3ti8A:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
ILE A 222
ARG A 224
 None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
LNV  A 901 (-4.1A)
 0.11A 3ticA-3ti8A:
65.2		 3ticA-3ti8A:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.18A 3ticB-3ti8A:
65.2		 3ticB-3ti8A:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_B_ZMRB1002_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.08A 3ticB-3ti8A:
65.2		 3ticB-3ti8A:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.17A 3ticC-3ti8A:
65.3		 3ticC-3ti8A:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_C_ZMRC1002_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.09A 3ticC-3ti8A:
65.3		 3ticC-3ti8A:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.17A 3ticD-3ti8A:
65.3		 3ticD-3ti8A:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_D_ZMRD1002_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.11A 3ticD-3ti8A:
65.3		 3ticD-3ti8A:
39.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 3tylA-3ti8A:
undetectable
3tylB-3ti8A:
undetectable		 3tylA-3ti8A:
22.64
3tylB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 3tylA-3ti8A:
undetectable
3tylB-3ti8A:
undetectable		 3tylA-3ti8A:
22.64
3tylB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 3tymA-3ti8A:
undetectable
3tymB-3ti8A:
undetectable		 3tymA-3ti8A:
22.64
3tymB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 3tymA-3ti8A:
undetectable
3tymB-3ti8A:
undetectable		 3tymA-3ti8A:
22.64
3tymB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 3tynA-3ti8A:
undetectable
3tynB-3ti8A:
undetectable		 3tynA-3ti8A:
22.64
3tynB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 3tynA-3ti8A:
undetectable
3tynB-3ti8A:
undetectable		 3tynA-3ti8A:
22.64
3tynB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 3tyoA-3ti8A:
undetectable
3tyoB-3ti8A:
undetectable		 3tyoA-3ti8A:
22.64
3tyoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 3tyoA-3ti8A:
undetectable
3tyoB-3ti8A:
undetectable		 3tyoA-3ti8A:
22.64
3tyoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.33A 3ufoA-3ti8A:
undetectable
3ufoB-3ti8A:
undetectable		 3ufoA-3ti8A:
22.64
3ufoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 3ufoA-3ti8A:
undetectable
3ufoB-3ti8A:
undetectable		 3ufoA-3ti8A:
22.64
3ufoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.33A 3ufpA-3ti8A:
undetectable
3ufpB-3ti8A:
undetectable		 3ufpA-3ti8A:
22.64
3ufpB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 3ufpA-3ti8A:
undetectable
3ufpB-3ti8A:
undetectable		 3ufpA-3ti8A:
22.64
3ufpB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 3ufqA-3ti8A:
undetectable
3ufqB-3ti8A:
undetectable		 3ufqA-3ti8A:
22.64
3ufqB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 3ufqA-3ti8A:
undetectable
3ufqB-3ti8A:
undetectable		 3ufqA-3ti8A:
22.64
3ufqB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.33A 3ufrA-3ti8A:
undetectable
3ufrB-3ti8A:
undetectable		 3ufrA-3ti8A:
22.64
3ufrB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.34A 3ufrA-3ti8A:
undetectable
3ufrB-3ti8A:
undetectable		 3ufrA-3ti8A:
22.64
3ufrB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.33A 3ufsA-3ti8A:
undetectable
3ufsB-3ti8A:
undetectable		 3ufsA-3ti8A:
22.64
3ufsB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 3ufsA-3ti8A:
undetectable
3ufsB-3ti8A:
undetectable		 3ufsA-3ti8A:
22.64
3ufsB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.32A 3uftA-3ti8A:
undetectable
3uftB-3ti8A:
undetectable		 3uftA-3ti8A:
22.64
3uftB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.31A 3uftA-3ti8A:
undetectable
3uftB-3ti8A:
undetectable		 3uftA-3ti8A:
22.64
3uftB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 3ufuA-3ti8A:
undetectable
3ufuB-3ti8A:
undetectable		 3ufuA-3ti8A:
22.64
3ufuB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 3ufuA-3ti8A:
undetectable
3ufuB-3ti8A:
undetectable		 3ufuA-3ti8A:
22.64
3ufuB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 3ufvA-3ti8A:
undetectable
3ufvB-3ti8A:
undetectable		 3ufvA-3ti8A:
22.64
3ufvB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 3ufvA-3ti8A:
undetectable
3ufvB-3ti8A:
undetectable		 3ufvA-3ti8A:
22.64
3ufvB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 3ufwA-3ti8A:
undetectable
3ufwB-3ti8A:
undetectable		 3ufwA-3ti8A:
22.64
3ufwB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 3ufwA-3ti8A:
undetectable
3ufwB-3ti8A:
undetectable		 3ufwA-3ti8A:
22.64
3ufwB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 VAL A 341
GLY A 342
TYR A 316
ASP A 293
 None
 1.47A 3w9tA-3ti8A:
undetectable		 3w9tA-3ti8A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 VAL A 341
GLY A 342
TYR A 316
ASP A 293
 None
 1.47A 3w9tB-3ti8A:
undetectable		 3w9tB-3ti8A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 VAL A 341
GLY A 342
TYR A 316
ASP A 293
 None
 1.47A 3w9tC-3ti8A:
undetectable		 3w9tC-3ti8A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 VAL A 341
GLY A 342
TYR A 316
ASP A 293
 None
 1.47A 3w9tD-3ti8A:
undetectable		 3w9tD-3ti8A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 VAL A 341
GLY A 342
TYR A 316
ASP A 293
 None
 1.47A 3w9tE-3ti8A:
undetectable		 3w9tE-3ti8A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 VAL A 341
GLY A 342
TYR A 316
ASP A 293
 None
 1.48A 3w9tF-3ti8A:
undetectable		 3w9tF-3ti8A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 5 VAL A 341
GLY A 342
TYR A 316
ASP A 293
 None
 1.47A 3w9tG-3ti8A:
undetectable		 3w9tG-3ti8A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLY A 363
PHE A 374
SER A 441
MET A 426
LEU A 424
 None
 1.36A 4a83A-3ti8A:
undetectable		 4a83A-3ti8A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 ASP A 460
SER A 441
SER A 440
GLY A 109
 None
 0.82A 4af0A-3ti8A:
undetectable		 4af0A-3ti8A:
21.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.21A 4b7nA-3ti8A:
69.6		 4b7nA-3ti8A:
48.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
 0.07A 4b7nA-3ti8A:
69.6		 4b7nA-3ti8A:
48.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.22A 4b7qA-3ti8A:
69.7		 4b7qA-3ti8A:
48.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
ILE A 222
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
 0.22A 4b7qA-3ti8A:
69.7		 4b7qA-3ti8A:
48.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.26A 4b7qB-3ti8A:
69.9		 4b7qB-3ti8A:
48.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_B_ZMRB601_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 LEU A 134
ARG A 152
ARG A 156
TRP A 178
 None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
 0.16A 4b7qB-3ti8A:
69.9		 4b7qB-3ti8A:
48.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.25A 4b7qC-3ti8A:
69.9		 4b7qC-3ti8A:
48.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 224
GLU A 276
GLU A 277
ARG A 118
TYR A 406
 LNV  A 901 (-4.1A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.0A)
LNV  A 901 (-4.8A)
 1.48A 4b7qC-3ti8A:
69.9		 4b7qC-3ti8A:
48.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
ILE A 222
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
 0.16A 4b7qC-3ti8A:
69.9		 4b7qC-3ti8A:
48.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_D_ZMRD601_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.25A 4b7qD-3ti8A:
70.2		 4b7qD-3ti8A:
48.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_D_ZMRD601_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.24A 4b7qD-3ti8A:
70.2		 4b7qD-3ti8A:
48.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 4c39A-3ti8A:
undetectable
4c39B-3ti8A:
undetectable		 4c39A-3ti8A:
22.64
4c39B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 4c39A-3ti8A:
undetectable
4c39B-3ti8A:
undetectable		 4c39A-3ti8A:
22.64
4c39B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.37A 4camA-3ti8A:
undetectable
4camB-3ti8A:
undetectable		 4camA-3ti8A:
22.64
4camB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 4camA-3ti8A:
undetectable
4camB-3ti8A:
undetectable		 4camA-3ti8A:
22.64
4camB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 4canA-3ti8A:
undetectable
4canB-3ti8A:
undetectable		 4canA-3ti8A:
22.64
4canB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 4canA-3ti8A:
undetectable
4canB-3ti8A:
undetectable		 4canA-3ti8A:
22.64
4canB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 4caoA-3ti8A:
undetectable
4caoB-3ti8A:
undetectable		 4caoA-3ti8A:
22.64
4caoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 4caoA-3ti8A:
undetectable
4caoB-3ti8A:
undetectable		 4caoA-3ti8A:
22.64
4caoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 4capA-3ti8A:
undetectable
4capB-3ti8A:
undetectable		 4capA-3ti8A:
22.64
4capB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 4capA-3ti8A:
undetectable
4capB-3ti8A:
undetectable		 4capA-3ti8A:
22.64
4capB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.46A 4caqA-3ti8A:
undetectable
4caqB-3ti8A:
undetectable		 4caqA-3ti8A:
22.64
4caqB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 4caqA-3ti8A:
undetectable
4caqB-3ti8A:
undetectable		 4caqA-3ti8A:
22.64
4caqB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.45A 4cdtA-3ti8A:
undetectable
4cdtB-3ti8A:
undetectable		 4cdtA-3ti8A:
22.64
4cdtB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4cdtA-3ti8A:
undetectable
4cdtB-3ti8A:
undetectable		 4cdtA-3ti8A:
22.64
4cdtB-3ti8A:
22.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.40A 4cpnA-3ti8A:
54.1		 4cpnA-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPN_A_ZMRA700_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
 0.11A 4cpnA-3ti8A:
54.1		 4cpnA-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.38A 4cpnB-3ti8A:
54.0		 4cpnB-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.43A 4cpzA-3ti8A:
53.7		 4cpzA-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		6 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
TYR A 406
 LNV  A 901 (-2.9A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-4.8A)
 1.49A 4cpzA-3ti8A:
53.7		 4cpzA-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_A_ZMRA1471_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ASP A 151
ARG A 152
ARG A 156
TRP A 178
 None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
 0.11A 4cpzA-3ti8A:
53.7		 4cpzA-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.38A 4cpzB-3ti8A:
53.6		 4cpzB-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_B_ZMRB1471_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ASP A 151
ARG A 152
ARG A 156
TRP A 178
 LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
 0.12A 4cpzB-3ti8A:
53.7		 4cpzB-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.38A 4cpzC-3ti8A:
53.8		 4cpzC-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
 0.16A 4cpzC-3ti8A:
53.8		 4cpzC-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.39A 4cpzD-3ti8A:
53.7		 4cpzD-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_D_ZMRD1471_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ASP A 151
ARG A 152
ARG A 156
TRP A 178
 LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
 0.13A 4cpzD-3ti8A:
53.7		 4cpzD-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.44A 4cpzE-3ti8A:
53.7		 4cpzE-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
 0.13A 4cpzE-3ti8A:
53.7		 4cpzE-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.44A 4cpzF-3ti8A:
53.7		 4cpzF-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
 0.11A 4cpzF-3ti8A:
53.7		 4cpzF-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.38A 4cpzG-3ti8A:
53.3		 4cpzG-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
 0.16A 4cpzG-3ti8A:
53.3		 4cpzG-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.45A 4cpzH-3ti8A:
53.6		 4cpzH-3ti8A:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
 0.15A 4cpzH-3ti8A:
53.6		 4cpzH-3ti8A:
32.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 4ctpA-3ti8A:
undetectable
4ctpB-3ti8A:
undetectable		 4ctpA-3ti8A:
22.64
4ctpB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 4ctpA-3ti8A:
undetectable
4ctpB-3ti8A:
undetectable		 4ctpA-3ti8A:
22.64
4ctpB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 4ctqA-3ti8A:
undetectable
4ctqB-3ti8A:
undetectable		 4ctqA-3ti8A:
22.64
4ctqB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 4ctqA-3ti8A:
undetectable
4ctqB-3ti8A:
undetectable		 4ctqA-3ti8A:
22.64
4ctqB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 4ctrA-3ti8A:
undetectable
4ctrB-3ti8A:
undetectable		 4ctrA-3ti8A:
22.64
4ctrB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.35A 4ctrA-3ti8A:
undetectable
4ctrB-3ti8A:
undetectable		 4ctrA-3ti8A:
22.64
4ctrB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 4cttA-3ti8A:
undetectable
4cttB-3ti8A:
undetectable		 4cttA-3ti8A:
22.64
4cttB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 4cttA-3ti8A:
undetectable
4cttB-3ti8A:
undetectable		 4cttA-3ti8A:
22.64
4cttB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 4ctuA-3ti8A:
undetectable
4ctuB-3ti8A:
undetectable		 4ctuA-3ti8A:
22.64
4ctuB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 4ctuA-3ti8A:
undetectable
4ctuB-3ti8A:
undetectable		 4ctuA-3ti8A:
22.64
4ctuB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.35A 4ctvA-3ti8A:
undetectable
4ctvB-3ti8A:
undetectable		 4ctvA-3ti8A:
22.64
4ctvB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 4ctvA-3ti8A:
undetectable
4ctvB-3ti8A:
undetectable		 4ctvA-3ti8A:
22.64
4ctvB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 4ctwA-3ti8A:
undetectable
4ctwB-3ti8A:
undetectable		 4ctwA-3ti8A:
22.64
4ctwB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 4ctwA-3ti8A:
undetectable
4ctwB-3ti8A:
undetectable		 4ctwA-3ti8A:
22.64
4ctwB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 4ctxA-3ti8A:
undetectable
4ctxB-3ti8A:
undetectable		 4ctxA-3ti8A:
22.64
4ctxB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4ctxA-3ti8A:
undetectable
4ctxB-3ti8A:
undetectable		 4ctxA-3ti8A:
22.64
4ctxB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 4cx5A-3ti8A:
undetectable
4cx5B-3ti8A:
undetectable		 4cx5A-3ti8A:
22.64
4cx5B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4cx5A-3ti8A:
undetectable
4cx5B-3ti8A:
undetectable		 4cx5A-3ti8A:
22.64
4cx5B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 4cx6A-3ti8A:
undetectable
4cx6B-3ti8A:
undetectable		 4cx6A-3ti8A:
22.64
4cx6B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 4cx6A-3ti8A:
undetectable
4cx6B-3ti8A:
undetectable		 4cx6A-3ti8A:
22.64
4cx6B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 4d1nA-3ti8A:
undetectable
4d1nB-3ti8A:
undetectable		 4d1nA-3ti8A:
21.75
4d1nB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 4d1nA-3ti8A:
undetectable
4d1nB-3ti8A:
undetectable		 4d1nA-3ti8A:
21.75
4d1nB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 4d1nC-3ti8A:
undetectable
4d1nD-3ti8A:
undetectable		 4d1nC-3ti8A:
21.75
4d1nD-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 4d1nC-3ti8A:
undetectable
4d1nD-3ti8A:
undetectable		 4d1nC-3ti8A:
21.75
4d1nD-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 4d2yA-3ti8A:
undetectable
4d2yB-3ti8A:
undetectable		 4d2yA-3ti8A:
22.64
4d2yB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4d2yA-3ti8A:
undetectable
4d2yB-3ti8A:
undetectable		 4d2yA-3ti8A:
22.64
4d2yB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 4d2zA-3ti8A:
undetectable
4d2zB-3ti8A:
undetectable		 4d2zA-3ti8A:
22.64
4d2zB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4d2zA-3ti8A:
undetectable
4d2zB-3ti8A:
undetectable		 4d2zA-3ti8A:
22.64
4d2zB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 4d30A-3ti8A:
undetectable
4d30B-3ti8A:
undetectable		 4d30A-3ti8A:
22.64
4d30B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 4d30A-3ti8A:
undetectable
4d30B-3ti8A:
undetectable		 4d30A-3ti8A:
22.64
4d30B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 4d31A-3ti8A:
undetectable
4d31B-3ti8A:
undetectable		 4d31A-3ti8A:
22.64
4d31B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 4d31A-3ti8A:
undetectable
4d31B-3ti8A:
undetectable		 4d31A-3ti8A:
22.64
4d31B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.37A 4d32A-3ti8A:
undetectable
4d32B-3ti8A:
undetectable		 4d32A-3ti8A:
22.64
4d32B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4d32A-3ti8A:
undetectable
4d32B-3ti8A:
undetectable		 4d32A-3ti8A:
22.64
4d32B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 4d3bA-3ti8A:
undetectable
4d3bB-3ti8A:
undetectable		 4d3bA-3ti8A:
22.64
4d3bB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.44A 4d3bA-3ti8A:
undetectable
4d3bB-3ti8A:
undetectable		 4d3bA-3ti8A:
22.64
4d3bB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 4d7oA-3ti8A:
undetectable
4d7oB-3ti8A:
undetectable		 4d7oA-3ti8A:
22.64
4d7oB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 4d7oA-3ti8A:
undetectable
4d7oB-3ti8A:
undetectable		 4d7oA-3ti8A:
22.64
4d7oB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 SER A 228
PHE A  97
VAL A 397
PHE A 374
 None
 0.94A 4dx7B-3ti8A:
undetectable		 4dx7B-3ti8A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 4euxA-3ti8A:
undetectable
4euxB-3ti8A:
undetectable		 4euxA-3ti8A:
22.64
4euxB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 4euxA-3ti8A:
undetectable
4euxB-3ti8A:
undetectable		 4euxA-3ti8A:
22.64
4euxB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 4fvwA-3ti8A:
undetectable
4fvwB-3ti8A:
undetectable		 4fvwA-3ti8A:
22.64
4fvwB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 4fvwA-3ti8A:
undetectable
4fvwB-3ti8A:
undetectable		 4fvwA-3ti8A:
22.64
4fvwB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 4fvxA-3ti8A:
undetectable
4fvxB-3ti8A:
undetectable		 4fvxA-3ti8A:
22.64
4fvxB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 4fvxA-3ti8A:
undetectable
4fvxB-3ti8A:
undetectable		 4fvxA-3ti8A:
22.64
4fvxB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 4fvyA-3ti8A:
undetectable
4fvyB-3ti8A:
undetectable		 4fvyA-3ti8A:
22.64
4fvyB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.44A 4fvyA-3ti8A:
undetectable
4fvyB-3ti8A:
undetectable		 4fvyA-3ti8A:
22.64
4fvyB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.45A 4fvzA-3ti8A:
undetectable
4fvzB-3ti8A:
undetectable		 4fvzA-3ti8A:
22.64
4fvzB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4fvzA-3ti8A:
undetectable
4fvzB-3ti8A:
undetectable		 4fvzA-3ti8A:
22.64
4fvzB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 4fw0A-3ti8A:
undetectable
4fw0B-3ti8A:
undetectable		 4fw0A-3ti8A:
22.64
4fw0B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 4fw0A-3ti8A:
undetectable
4fw0B-3ti8A:
undetectable		 4fw0A-3ti8A:
22.64
4fw0B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 4gqeA-3ti8A:
undetectable
4gqeB-3ti8A:
undetectable		 4gqeA-3ti8A:
22.64
4gqeB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 4gqeA-3ti8A:
undetectable
4gqeB-3ti8A:
undetectable		 4gqeA-3ti8A:
22.64
4gqeB-3ti8A:
22.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 152
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.38A 4i00A-3ti8A:
65.2		 4i00A-3ti8A:
45.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 156
TRP A 178
ILE A 222
ASN A 294
 None
LNV  A 901 (-4.0A)
None
None
LNV  A 901 (-4.0A)
 0.91A 4i00A-3ti8A:
65.2		 4i00A-3ti8A:
45.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 4imtA-3ti8A:
undetectable
4imtB-3ti8A:
undetectable		 4imtA-3ti8A:
22.64
4imtB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.34A 4imtA-3ti8A:
undetectable
4imtB-3ti8A:
undetectable		 4imtA-3ti8A:
22.64
4imtB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 4imuA-3ti8A:
undetectable
4imuB-3ti8A:
undetectable		 4imuA-3ti8A:
22.64
4imuB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA809_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.34A 4imuA-3ti8A:
undetectable
4imuB-3ti8A:
undetectable		 4imuA-3ti8A:
22.64
4imuB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.33A 4imwA-3ti8A:
undetectable
4imwB-3ti8A:
undetectable		 4imwA-3ti8A:
22.64
4imwB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.30A 4imwA-3ti8A:
undetectable
4imwB-3ti8A:
undetectable		 4imwA-3ti8A:
22.64
4imwB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.37A 4jseA-3ti8A:
undetectable
4jseB-3ti8A:
undetectable		 4jseA-3ti8A:
22.64
4jseB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 4jseA-3ti8A:
undetectable
4jseB-3ti8A:
undetectable		 4jseA-3ti8A:
22.64
4jseB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.36A 4jsfA-3ti8A:
undetectable
4jsfB-3ti8A:
undetectable		 4jsfA-3ti8A:
22.64
4jsfB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 4jsfA-3ti8A:
undetectable
4jsfB-3ti8A:
undetectable		 4jsfA-3ti8A:
22.64
4jsfB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 4jsgA-3ti8A:
undetectable
4jsgB-3ti8A:
undetectable		 4jsgA-3ti8A:
22.64
4jsgB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 4jsgA-3ti8A:
undetectable
4jsgB-3ti8A:
undetectable		 4jsgA-3ti8A:
22.64
4jsgB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.34A 4jshA-3ti8A:
undetectable
4jshB-3ti8A:
undetectable		 4jshA-3ti8A:
22.64
4jshB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 4jshA-3ti8A:
undetectable
4jshB-3ti8A:
undetectable		 4jshA-3ti8A:
22.64
4jshB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.34A 4jsiA-3ti8A:
undetectable
4jsiB-3ti8A:
undetectable		 4jsiA-3ti8A:
22.64
4jsiB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 4jsiA-3ti8A:
undetectable
4jsiB-3ti8A:
undetectable		 4jsiA-3ti8A:
22.64
4jsiB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.47A 4jsjA-3ti8A:
undetectable
4jsjB-3ti8A:
undetectable		 4jsjA-3ti8A:
22.64
4jsjB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 4jsjA-3ti8A:
undetectable
4jsjB-3ti8A:
undetectable		 4jsjA-3ti8A:
22.64
4jsjB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 4k5dA-3ti8A:
undetectable
4k5dB-3ti8A:
undetectable		 4k5dA-3ti8A:
22.64
4k5dB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 4k5dA-3ti8A:
undetectable
4k5dB-3ti8A:
undetectable		 4k5dA-3ti8A:
22.64
4k5dB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 4k5eA-3ti8A:
undetectable
4k5eB-3ti8A:
undetectable		 4k5eA-3ti8A:
22.64
4k5eB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 4k5eA-3ti8A:
undetectable
4k5eB-3ti8A:
undetectable		 4k5eA-3ti8A:
22.64
4k5eB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 4k5fA-3ti8A:
undetectable
4k5fB-3ti8A:
undetectable		 4k5fA-3ti8A:
22.64
4k5fB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 4k5fA-3ti8A:
undetectable
4k5fB-3ti8A:
undetectable		 4k5fA-3ti8A:
22.64
4k5fB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 4k5gA-3ti8A:
undetectable
4k5gB-3ti8A:
undetectable		 4k5gA-3ti8A:
22.64
4k5gB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 4k5gA-3ti8A:
undetectable
4k5gB-3ti8A:
undetectable		 4k5gA-3ti8A:
22.64
4k5gB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 4kchA-3ti8A:
undetectable
4kchB-3ti8A:
undetectable		 4kchA-3ti8A:
22.64
4kchB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 4kchA-3ti8A:
undetectable
4kchB-3ti8A:
undetectable		 4kchA-3ti8A:
22.64
4kchB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 4kciA-3ti8A:
undetectable
4kciB-3ti8A:
undetectable		 4kciA-3ti8A:
22.64
4kciB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 4kciA-3ti8A:
undetectable
4kciB-3ti8A:
undetectable		 4kciA-3ti8A:
22.64
4kciB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 4kcjA-3ti8A:
undetectable
4kcjB-3ti8A:
undetectable		 4kcjA-3ti8A:
22.64
4kcjB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 4kcjA-3ti8A:
undetectable
4kcjB-3ti8A:
undetectable		 4kcjA-3ti8A:
22.64
4kcjB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.45A 4kckA-3ti8A:
undetectable
4kckB-3ti8A:
undetectable		 4kckA-3ti8A:
22.64
4kckB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4kckA-3ti8A:
undetectable
4kckB-3ti8A:
undetectable		 4kckA-3ti8A:
22.64
4kckB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 4kclA-3ti8A:
undetectable
4kclB-3ti8A:
undetectable		 4kclA-3ti8A:
22.64
4kclB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 4kclA-3ti8A:
undetectable
4kclB-3ti8A:
undetectable		 4kclA-3ti8A:
22.64
4kclB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 4kcmA-3ti8A:
undetectable
4kcmB-3ti8A:
undetectable		 4kcmA-3ti8A:
22.64
4kcmB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 4kcmA-3ti8A:
undetectable
4kcmB-3ti8A:
undetectable		 4kcmA-3ti8A:
22.64
4kcmB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 4kcnA-3ti8A:
undetectable
4kcnB-3ti8A:
undetectable		 4kcnA-3ti8A:
22.64
4kcnB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4kcnA-3ti8A:
undetectable
4kcnB-3ti8A:
undetectable		 4kcnA-3ti8A:
22.64
4kcnB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 4kcoA-3ti8A:
undetectable
4kcoB-3ti8A:
undetectable		 4kcoA-3ti8A:
22.64
4kcoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 4kcoA-3ti8A:
undetectable
4kcoB-3ti8A:
undetectable		 4kcoA-3ti8A:
22.64
4kcoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 4luxA-3ti8A:
undetectable
4luxB-3ti8A:
undetectable		 4luxA-3ti8A:
22.64
4luxB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 4luxA-3ti8A:
undetectable
4luxB-3ti8A:
undetectable		 4luxA-3ti8A:
22.64
4luxB-3ti8A:
22.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.21A 4mwrA-3ti8A:
65.1		 4mwrA-3ti8A:
43.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ASP A 151
ARG A 152
TRP A 178
ILE A 222
 None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
None
None
 0.13A 4mwrA-3ti8A:
65.1		 4mwrA-3ti8A:
43.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ASP A 151
ARG A 152
ILE A 222
ARG A 224
GLU A 227
 LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
None
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
 1.34A 4mwvA-3ti8A:
64.9		 4mwvA-3ti8A:
43.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
TRP A 178
ILE A 222
ARG A 224
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 901 (-3.6A)
None
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
LNV  A 901 (-4.1A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.8A)
 0.42A 4mwvA-3ti8A:
64.9		 4mwvA-3ti8A:
43.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
GLU A 227
ARG A 371
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
 0.14A 4mwvA-3ti8A:
64.9		 4mwvA-3ti8A:
43.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.31A 4mwxA-3ti8A:
64.9		 4mwxA-3ti8A:
43.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		6 / 12 ARG A 224
ALA A 246
GLU A 276
GLU A 277
ARG A 118
TYR A 406
 LNV  A 901 (-4.1A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.0A)
LNV  A 901 (-4.8A)
 1.48A 4mwxA-3ti8A:
64.9		 4mwxA-3ti8A:
43.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
TRP A 178
ILE A 222
 LNV  A 901 (-4.0A)
None
None
 0.11A 4mwxA-3ti8A:
64.9		 4mwxA-3ti8A:
43.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MX0_A_BCZA513_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
TRP A 178
SER A 179
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
TYR A 406
 LNV  A 901 (-3.6A)
None
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
LNV  A 901 ( 4.6A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-4.8A)
 0.47A 4mx0A-3ti8A:
64.8		 4mx0A-3ti8A:
43.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
ASP A 151
ARG A 371
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
 0.14A 4mx0A-3ti8A:
64.7		 4mx0A-3ti8A:
43.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.47A 4uchA-3ti8A:
undetectable
4uchB-3ti8A:
undetectable		 4uchA-3ti8A:
22.03
4uchB-3ti8A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4uchA-3ti8A:
undetectable
4uchB-3ti8A:
undetectable		 4uchA-3ti8A:
22.03
4uchB-3ti8A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4ugzA-3ti8A:
undetectable
4ugzB-3ti8A:
undetectable		 4ugzA-3ti8A:
22.64
4ugzB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4uh0A-3ti8A:
undetectable
4uh0B-3ti8A:
undetectable		 4uh0A-3ti8A:
22.64
4uh0B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 4uh1A-3ti8A:
undetectable
4uh1B-3ti8A:
undetectable		 4uh1A-3ti8A:
22.64
4uh1B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4uh1A-3ti8A:
undetectable
4uh1B-3ti8A:
undetectable		 4uh1A-3ti8A:
22.64
4uh1B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 4uh2A-3ti8A:
undetectable
4uh2B-3ti8A:
undetectable		 4uh2A-3ti8A:
22.64
4uh2B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 4uh2A-3ti8A:
undetectable
4uh2B-3ti8A:
undetectable		 4uh2A-3ti8A:
22.64
4uh2B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 4uh3A-3ti8A:
undetectable
4uh3B-3ti8A:
undetectable		 4uh3A-3ti8A:
22.64
4uh3B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 4uh4A-3ti8A:
undetectable
4uh4B-3ti8A:
undetectable		 4uh4A-3ti8A:
22.64
4uh4B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 4uh4A-3ti8A:
undetectable
4uh4B-3ti8A:
undetectable		 4uh4A-3ti8A:
22.64
4uh4B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 4uh5A-3ti8A:
undetectable
4uh5B-3ti8A:
undetectable		 4uh5A-3ti8A:
21.75
4uh5B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 4uh5A-3ti8A:
undetectable
4uh5B-3ti8A:
undetectable		 4uh5A-3ti8A:
21.75
4uh5B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.45A 4uh6A-3ti8A:
undetectable
4uh6B-3ti8A:
undetectable		 4uh6A-3ti8A:
21.75
4uh6B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 4uh6A-3ti8A:
undetectable
4uh6B-3ti8A:
undetectable		 4uh6A-3ti8A:
21.75
4uh6B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 4upmA-3ti8A:
undetectable
4upmB-3ti8A:
undetectable		 4upmA-3ti8A:
22.64
4upmB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 4upmA-3ti8A:
undetectable
4upmB-3ti8A:
undetectable		 4upmA-3ti8A:
22.64
4upmB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 4upnA-3ti8A:
undetectable
4upnB-3ti8A:
undetectable		 4upnA-3ti8A:
22.64
4upnB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4upnA-3ti8A:
undetectable
4upnB-3ti8A:
undetectable		 4upnA-3ti8A:
22.64
4upnB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 4upoA-3ti8A:
undetectable
4upoB-3ti8A:
undetectable		 4upoA-3ti8A:
22.64
4upoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.44A 4upoA-3ti8A:
undetectable
4upoB-3ti8A:
undetectable		 4upoA-3ti8A:
22.64
4upoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 4uppA-3ti8A:
undetectable
4uppB-3ti8A:
undetectable		 4uppA-3ti8A:
22.64
4uppB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 4uppA-3ti8A:
undetectable
4uppB-3ti8A:
undetectable		 4uppA-3ti8A:
22.64
4uppB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 4v3uA-3ti8A:
undetectable
4v3uB-3ti8A:
undetectable		 4v3uA-3ti8A:
21.75
4v3uB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 4v3uA-3ti8A:
undetectable
4v3uB-3ti8A:
undetectable		 4v3uA-3ti8A:
21.75
4v3uB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 4v3uC-3ti8A:
undetectable
4v3uD-3ti8A:
undetectable		 4v3uC-3ti8A:
21.75
4v3uD-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 4v3uC-3ti8A:
undetectable
4v3uD-3ti8A:
undetectable		 4v3uC-3ti8A:
21.75
4v3uD-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 4v3vA-3ti8A:
undetectable
4v3vB-3ti8A:
undetectable		 4v3vA-3ti8A:
22.64
4v3vB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 4v3vA-3ti8A:
undetectable
4v3vB-3ti8A:
undetectable		 4v3vA-3ti8A:
22.64
4v3vB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.32A 4v3wA-3ti8A:
undetectable
4v3wB-3ti8A:
undetectable		 4v3wA-3ti8A:
22.64
4v3wB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.35A 4v3wA-3ti8A:
undetectable
4v3wB-3ti8A:
undetectable		 4v3wA-3ti8A:
22.64
4v3wB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 4v3xA-3ti8A:
undetectable
4v3xB-3ti8A:
undetectable		 4v3xA-3ti8A:
22.64
4v3xB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 4v3xA-3ti8A:
undetectable
4v3xB-3ti8A:
undetectable		 4v3xA-3ti8A:
22.64
4v3xB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 4v3yA-3ti8A:
undetectable
4v3yB-3ti8A:
undetectable		 4v3yA-3ti8A:
22.64
4v3yB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 4v3zA-3ti8A:
undetectable
4v3zB-3ti8A:
undetectable		 4v3zA-3ti8A:
22.64
4v3zB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 4v3zA-3ti8A:
undetectable
4v3zB-3ti8A:
undetectable		 4v3zA-3ti8A:
22.64
4v3zB-3ti8A:
22.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
TYR A 347
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-4.0A)
LNV  A 901 ( 4.7A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.52A 4wa5A-3ti8A:
72.8		 4wa5A-3ti8A:
69.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ASP A 151
ARG A 371
TYR A 406
ARG A 292
TYR A 347
 LNV  A 901 (-3.4A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
LNV  A 901 (-2.8A)
LNV  A 901 ( 4.7A)
 0.92A 4wa5A-3ti8A:
72.8		 4wa5A-3ti8A:
69.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA5_A_ZMRA501_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 ARG A 152
ARG A 156
TRP A 178
ILE A 222
ARG A 224
 LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
None
None
LNV  A 901 (-4.1A)
 0.55A 4wa5A-3ti8A:
72.8		 4wa5A-3ti8A:
69.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 227
GLU A 119
LEU A 424
GLU A 276
ASP A 151
 LNV  A 901 (-3.4A)
LNV  A 901 (-3.6A)
None
LNV  A 901 (-2.9A)
LNV  A 901 (-3.4A)
 1.03A 4xe5A-3ti8A:
undetectable		 4xe5A-3ti8A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.33A 5ad4A-3ti8A:
undetectable
5ad4B-3ti8A:
undetectable		 5ad4A-3ti8A:
22.64
5ad4B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.31A 5ad4A-3ti8A:
undetectable
5ad4B-3ti8A:
undetectable		 5ad4A-3ti8A:
22.64
5ad4B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 5ad5A-3ti8A:
undetectable
5ad5B-3ti8A:
undetectable		 5ad5A-3ti8A:
22.64
5ad5B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 5ad5A-3ti8A:
undetectable
5ad5B-3ti8A:
undetectable		 5ad5A-3ti8A:
22.64
5ad5B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.36A 5ad6A-3ti8A:
undetectable
5ad6B-3ti8A:
undetectable		 5ad6A-3ti8A:
22.64
5ad6B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 5ad6A-3ti8A:
undetectable
5ad6B-3ti8A:
undetectable		 5ad6A-3ti8A:
22.64
5ad6B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5ad7A-3ti8A:
undetectable
5ad7B-3ti8A:
undetectable		 5ad7A-3ti8A:
22.64
5ad7B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 5ad9A-3ti8A:
undetectable
5ad9B-3ti8A:
undetectable		 5ad9A-3ti8A:
22.64
5ad9B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5ad9A-3ti8A:
undetectable
5ad9B-3ti8A:
undetectable		 5ad9A-3ti8A:
22.64
5ad9B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 5adaA-3ti8A:
undetectable
5adaB-3ti8A:
undetectable		 5adaA-3ti8A:
22.64
5adaB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 5adbA-3ti8A:
undetectable
5adbB-3ti8A:
undetectable		 5adbA-3ti8A:
22.64
5adbB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 5adcA-3ti8A:
undetectable
5adcB-3ti8A:
undetectable		 5adcA-3ti8A:
22.64
5adcB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 5adcA-3ti8A:
undetectable
5adcB-3ti8A:
undetectable		 5adcA-3ti8A:
22.64
5adcB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 5adfA-3ti8A:
undetectable
5adfB-3ti8A:
undetectable		 5adfA-3ti8A:
21.75
5adfB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 5adgA-3ti8A:
undetectable
5adgB-3ti8A:
undetectable		 5adgA-3ti8A:
21.75
5adgB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 5adgA-3ti8A:
undetectable
5adgB-3ti8A:
undetectable		 5adgA-3ti8A:
21.75
5adgB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 5adiA-3ti8A:
undetectable
5adiB-3ti8A:
undetectable		 5adiA-3ti8A:
21.75
5adiB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 5agkA-3ti8A:
undetectable
5agkB-3ti8A:
undetectable		 5agkA-3ti8A:
22.64
5agkB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5agkA-3ti8A:
undetectable
5agkB-3ti8A:
undetectable		 5agkA-3ti8A:
22.64
5agkB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 5aglA-3ti8A:
undetectable
5aglB-3ti8A:
undetectable		 5aglA-3ti8A:
22.64
5aglB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 5aglA-3ti8A:
undetectable
5aglB-3ti8A:
undetectable		 5aglA-3ti8A:
22.64
5aglB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 5agmA-3ti8A:
undetectable
5agmB-3ti8A:
undetectable		 5agmA-3ti8A:
22.64
5agmB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5agmA-3ti8A:
undetectable
5agmB-3ti8A:
undetectable		 5agmA-3ti8A:
22.64
5agmB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 5agnA-3ti8A:
undetectable
5agnB-3ti8A:
undetectable		 5agnA-3ti8A:
22.64
5agnB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 5agnA-3ti8A:
undetectable
5agnB-3ti8A:
undetectable		 5agnA-3ti8A:
22.64
5agnB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 5agoA-3ti8A:
undetectable
5agoB-3ti8A:
undetectable		 5agoA-3ti8A:
22.64
5agoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5agoA-3ti8A:
undetectable
5agoB-3ti8A:
undetectable		 5agoA-3ti8A:
22.64
5agoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.45A 5agpA-3ti8A:
undetectable
5agpB-3ti8A:
undetectable		 5agpA-3ti8A:
22.64
5agpB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5agpA-3ti8A:
undetectable
5agpB-3ti8A:
undetectable		 5agpA-3ti8A:
22.64
5agpB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.35A 5fvpA-3ti8A:
undetectable
5fvpB-3ti8A:
undetectable		 5fvpA-3ti8A:
22.64
5fvpB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 5fvpA-3ti8A:
undetectable
5fvpB-3ti8A:
undetectable		 5fvpA-3ti8A:
22.64
5fvpB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.45A 5fvqA-3ti8A:
undetectable
5fvqB-3ti8A:
undetectable		 5fvqA-3ti8A:
22.64
5fvqB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 5fvqA-3ti8A:
undetectable
5fvqB-3ti8A:
undetectable		 5fvqA-3ti8A:
22.64
5fvqB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 5fvrA-3ti8A:
undetectable
5fvrB-3ti8A:
undetectable		 5fvrA-3ti8A:
22.64
5fvrB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 5fvrA-3ti8A:
undetectable
5fvrB-3ti8A:
undetectable		 5fvrA-3ti8A:
22.64
5fvrB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 5fvsA-3ti8A:
undetectable
5fvsB-3ti8A:
undetectable		 5fvsA-3ti8A:
22.64
5fvsB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5fvsA-3ti8A:
undetectable
5fvsB-3ti8A:
undetectable		 5fvsA-3ti8A:
22.64
5fvsB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 5fvtA-3ti8A:
undetectable
5fvtB-3ti8A:
undetectable		 5fvtA-3ti8A:
22.64
5fvtB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 5fvtA-3ti8A:
undetectable
5fvtB-3ti8A:
undetectable		 5fvtA-3ti8A:
22.64
5fvtB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 5fvuA-3ti8A:
undetectable
5fvuB-3ti8A:
undetectable		 5fvuA-3ti8A:
21.75
5fvuB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 5fvuA-3ti8A:
undetectable
5fvuB-3ti8A:
undetectable		 5fvuA-3ti8A:
21.75
5fvuB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 5fvvA-3ti8A:
undetectable
5fvvB-3ti8A:
undetectable		 5fvvA-3ti8A:
21.75
5fvvB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5fvvA-3ti8A:
undetectable
5fvvB-3ti8A:
undetectable		 5fvvA-3ti8A:
21.75
5fvvB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 5fvwA-3ti8A:
undetectable
5fvwB-3ti8A:
undetectable		 5fvwA-3ti8A:
21.75
5fvwB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5fvwA-3ti8A:
undetectable
5fvwB-3ti8A:
undetectable		 5fvwA-3ti8A:
21.75
5fvwB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 5fvxA-3ti8A:
undetectable
5fvxB-3ti8A:
undetectable		 5fvxA-3ti8A:
21.75
5fvxB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.37A 5fw0A-3ti8A:
undetectable
5fw0B-3ti8A:
undetectable		 5fw0A-3ti8A:
22.64
5fw0B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 5fw0A-3ti8A:
undetectable
5fw0B-3ti8A:
undetectable		 5fw0A-3ti8A:
22.64
5fw0B-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 5g0nA-3ti8A:
undetectable
5g0nB-3ti8A:
undetectable		 5g0nA-3ti8A:
22.64
5g0nB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 5g0nA-3ti8A:
undetectable
5g0nB-3ti8A:
undetectable		 5g0nA-3ti8A:
22.64
5g0nB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 5g0oA-3ti8A:
undetectable
5g0oB-3ti8A:
undetectable		 5g0oA-3ti8A:
22.64
5g0oB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 5g0oA-3ti8A:
undetectable
5g0oB-3ti8A:
undetectable		 5g0oA-3ti8A:
22.64
5g0oB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 ILE A 106
GLY A 105
PHE A 446
PHE A 374
 None
 0.60A 5hieA-3ti8A:
undetectable		 5hieA-3ti8A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 ILE A 106
GLY A 105
PHE A 446
PHE A 374
 None
 0.92A 5hieD-3ti8A:
undetectable		 5hieD-3ti8A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_A_KANA600_1
(BIFUNCTIONAL AAC/APH)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 LNV  A 901 ( 4.6A)
None
LNV  A 901 (-3.6A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.4A)
 1.46A 5iqbA-3ti8A:
undetectable		 5iqbA-3ti8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_B_KANB600_1
(BIFUNCTIONAL AAC/APH)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 11 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 LNV  A 901 ( 4.6A)
None
LNV  A 901 (-3.6A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.4A)
 1.45A 5iqbB-3ti8A:
0.4		 5iqbB-3ti8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_C_KANC600_1
(BIFUNCTIONAL AAC/APH)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 11 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 LNV  A 901 ( 4.6A)
None
LNV  A 901 (-3.6A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.4A)
 1.46A 5iqbC-3ti8A:
0.0		 5iqbC-3ti8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_D_KAND600_1
(BIFUNCTIONAL AAC/APH)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 LNV  A 901 ( 4.6A)
None
LNV  A 901 (-3.6A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.4A)
 1.46A 5iqbD-3ti8A:
undetectable		 5iqbD-3ti8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQC_A_51GA600_1
(BIFUNCTIONAL AAC/APH)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 10 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 LNV  A 901 ( 4.6A)
None
LNV  A 901 (-3.6A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.4A)
 1.44A 5iqcA-3ti8A:
0.0		 5iqcA-3ti8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQC_B_51GB600_1
(BIFUNCTIONAL AAC/APH)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 10 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 LNV  A 901 ( 4.6A)
None
LNV  A 901 (-3.6A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.4A)
 1.47A 5iqcB-3ti8A:
0.3		 5iqcB-3ti8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQC_C_51GC600_1
(BIFUNCTIONAL AAC/APH)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 10 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 LNV  A 901 ( 4.6A)
None
LNV  A 901 (-3.6A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.4A)
 1.46A 5iqcC-3ti8A:
0.0		 5iqcC-3ti8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQC_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 10 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 LNV  A 901 ( 4.6A)
None
LNV  A 901 (-3.6A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.4A)
 1.45A 5iqcD-3ti8A:
0.2		 5iqcD-3ti8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 11 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 LNV  A 901 ( 4.6A)
None
LNV  A 901 (-3.6A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.4A)
 1.47A 5iqeA-3ti8A:
0.0		 5iqeA-3ti8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 LNV  A 901 ( 4.6A)
None
LNV  A 901 (-3.6A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.4A)
 1.46A 5iqeD-3ti8A:
undetectable		 5iqeD-3ti8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQG_A_51GA600_1
(BIFUNCTIONAL AAC/APH)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 10 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 LNV  A 901 ( 4.6A)
None
LNV  A 901 (-3.6A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.4A)
 1.49A 5iqgA-3ti8A:
0.0		 5iqgA-3ti8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQG_B_51GB600_1
(BIFUNCTIONAL AAC/APH)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 10 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 LNV  A 901 ( 4.6A)
None
LNV  A 901 (-3.6A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.4A)
 1.49A 5iqgB-3ti8A:
0.0		 5iqgB-3ti8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQG_C_51GC600_1
(BIFUNCTIONAL AAC/APH)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 10 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 LNV  A 901 ( 4.6A)
None
LNV  A 901 (-3.6A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.4A)
 1.49A 5iqgC-3ti8A:
1.0		 5iqgC-3ti8A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQG_D_51GD600_1
(BIFUNCTIONAL AAC/APH)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 10 SER A 179
ASP A 198
GLU A 119
GLU A 277
GLU A 227
 LNV  A 901 ( 4.6A)
None
LNV  A 901 (-3.6A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-3.4A)
 1.48A 5iqgD-3ti8A:
0.7		 5iqgD-3ti8A:
22.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.29A 5l17A-3ti8A:
65.2		 5l17A-3ti8A:
43.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L17_A_ZMRA512_2
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 LEU A 134
ARG A 152
TRP A 178
ILE A 222
 None
LNV  A 901 (-4.0A)
None
None
 0.18A 5l17A-3ti8A:
65.2		 5l17A-3ti8A:
43.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 192
ILE A 194
VAL A 215
ALA A 203
 None
 0.75A 5ospA-3ti8A:
undetectable		 5ospA-3ti8A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 192
ILE A 194
VAL A 215
ALA A 203
 None
 0.75A 5osrA-3ti8A:
undetectable		 5osrA-3ti8A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 5unrA-3ti8A:
undetectable
5unrB-3ti8A:
undetectable		 5unrA-3ti8A:
22.64
5unrB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 5unsA-3ti8A:
undetectable
5unsB-3ti8A:
undetectable		 5unsA-3ti8A:
22.64
5unsB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 5unsA-3ti8A:
undetectable
5unsB-3ti8A:
undetectable		 5unsA-3ti8A:
22.64
5unsB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 5untA-3ti8A:
undetectable
5untB-3ti8A:
undetectable		 5untA-3ti8A:
22.64
5untB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.45A 5untA-3ti8A:
undetectable
5untB-3ti8A:
undetectable		 5untA-3ti8A:
22.64
5untB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.49A 5unuA-3ti8A:
undetectable
5unuB-3ti8A:
undetectable		 5unuA-3ti8A:
22.64
5unuB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 5unvA-3ti8A:
undetectable
5unvB-3ti8A:
undetectable		 5unvA-3ti8A:
22.64
5unvB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 5unwA-3ti8A:
undetectable
5unwB-3ti8A:
undetectable		 5unwA-3ti8A:
22.64
5unwB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.46A 5unxA-3ti8A:
undetectable
5unxB-3ti8A:
undetectable		 5unxA-3ti8A:
22.64
5unxB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 5unyA-3ti8A:
undetectable
5unyB-3ti8A:
undetectable		 5unyA-3ti8A:
22.64
5unyB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 5uo1A-3ti8A:
undetectable
5uo1B-3ti8A:
undetectable		 5uo1A-3ti8A:
21.75
5uo1B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 5uo1A-3ti8A:
undetectable
5uo1B-3ti8A:
undetectable		 5uo1A-3ti8A:
21.75
5uo1B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 5uo2A-3ti8A:
undetectable
5uo2B-3ti8A:
undetectable		 5uo2A-3ti8A:
21.75
5uo2B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5uo2A-3ti8A:
undetectable
5uo2B-3ti8A:
undetectable		 5uo2A-3ti8A:
21.75
5uo2B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.45A 5uo3A-3ti8A:
undetectable
5uo3B-3ti8A:
undetectable		 5uo3A-3ti8A:
21.75
5uo3B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 5uo4A-3ti8A:
undetectable
5uo4B-3ti8A:
undetectable		 5uo4A-3ti8A:
21.75
5uo4B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5uo4A-3ti8A:
undetectable
5uo4B-3ti8A:
undetectable		 5uo4A-3ti8A:
21.75
5uo4B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 5uo5A-3ti8A:
undetectable
5uo5B-3ti8A:
undetectable		 5uo5A-3ti8A:
21.75
5uo5B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 5uo5A-3ti8A:
undetectable
5uo5B-3ti8A:
undetectable		 5uo5A-3ti8A:
21.75
5uo5B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 5uo6A-3ti8A:
undetectable
5uo6B-3ti8A:
undetectable		 5uo6A-3ti8A:
21.75
5uo6B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 5uo7A-3ti8A:
undetectable
5uo7B-3ti8A:
undetectable		 5uo7A-3ti8A:
21.75
5uo7B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 5vuiA-3ti8A:
undetectable
5vuiB-3ti8A:
undetectable		 5vuiA-3ti8A:
22.64
5vuiB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5vuiA-3ti8A:
undetectable
5vuiB-3ti8A:
undetectable		 5vuiA-3ti8A:
22.64
5vuiB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.37A 5vujA-3ti8A:
undetectable
5vujB-3ti8A:
undetectable		 5vujA-3ti8A:
22.64
5vujB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 5vujA-3ti8A:
undetectable
5vujB-3ti8A:
undetectable		 5vujA-3ti8A:
22.64
5vujB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 5vulA-3ti8A:
undetectable
5vulB-3ti8A:
undetectable		 5vulA-3ti8A:
22.64
5vulB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5vulA-3ti8A:
undetectable
5vulB-3ti8A:
undetectable		 5vulA-3ti8A:
22.64
5vulB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 5vumA-3ti8A:
undetectable
5vumB-3ti8A:
undetectable		 5vumA-3ti8A:
22.64
5vumB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 5vumA-3ti8A:
undetectable
5vumB-3ti8A:
undetectable		 5vumA-3ti8A:
22.64
5vumB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 5vunA-3ti8A:
undetectable
5vunB-3ti8A:
undetectable		 5vunA-3ti8A:
22.64
5vunB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 5vunA-3ti8A:
undetectable
5vunB-3ti8A:
undetectable		 5vunA-3ti8A:
22.64
5vunB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.37A 5vuoA-3ti8A:
undetectable
5vuoB-3ti8A:
undetectable		 5vuoA-3ti8A:
22.64
5vuoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5vuoA-3ti8A:
undetectable
5vuoB-3ti8A:
undetectable		 5vuoA-3ti8A:
22.64
5vuoB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 5vupA-3ti8A:
undetectable
5vupB-3ti8A:
undetectable		 5vupA-3ti8A:
22.64
5vupB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5vupA-3ti8A:
undetectable
5vupB-3ti8A:
undetectable		 5vupA-3ti8A:
22.64
5vupB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.37A 5vuqA-3ti8A:
undetectable
5vuqB-3ti8A:
undetectable		 5vuqA-3ti8A:
22.64
5vuqB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 5vuqA-3ti8A:
undetectable
5vuqB-3ti8A:
undetectable		 5vuqA-3ti8A:
22.64
5vuqB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 5vurA-3ti8A:
undetectable
5vurB-3ti8A:
undetectable		 5vurA-3ti8A:
22.64
5vurB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 5vusA-3ti8A:
undetectable
5vusB-3ti8A:
undetectable		 5vusA-3ti8A:
22.64
5vusB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 5vusA-3ti8A:
undetectable
5vusB-3ti8A:
undetectable		 5vusA-3ti8A:
22.64
5vusB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 5vutA-3ti8A:
undetectable
5vutB-3ti8A:
undetectable		 5vutA-3ti8A:
22.64
5vutB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 5vutA-3ti8A:
undetectable
5vutB-3ti8A:
undetectable		 5vutA-3ti8A:
22.64
5vutB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 5vuuA-3ti8A:
undetectable
5vuuB-3ti8A:
undetectable		 5vuuA-3ti8A:
22.64
5vuuB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 5vuuA-3ti8A:
undetectable
5vuuB-3ti8A:
undetectable		 5vuuA-3ti8A:
22.64
5vuuB-3ti8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.40A 5vuvA-3ti8A:
undetectable
5vuvB-3ti8A:
undetectable		 5vuvA-3ti8A:
21.75
5vuvB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 5vuvA-3ti8A:
undetectable
5vuvB-3ti8A:
undetectable		 5vuvA-3ti8A:
21.75
5vuvB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 5vuwA-3ti8A:
undetectable
5vuwB-3ti8A:
undetectable		 5vuwA-3ti8A:
21.75
5vuwB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 5vuwA-3ti8A:
undetectable
5vuwB-3ti8A:
undetectable		 5vuwA-3ti8A:
21.75
5vuwB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 5vuxA-3ti8A:
undetectable
5vuxB-3ti8A:
undetectable		 5vuxA-3ti8A:
21.75
5vuxB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 5vuyA-3ti8A:
undetectable
5vuyB-3ti8A:
undetectable		 5vuyA-3ti8A:
21.75
5vuyB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.35A 5vuyA-3ti8A:
undetectable
5vuyB-3ti8A:
undetectable		 5vuyA-3ti8A:
21.75
5vuyB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 5vuzA-3ti8A:
undetectable
5vuzB-3ti8A:
undetectable		 5vuzA-3ti8A:
21.75
5vuzB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 5vuzA-3ti8A:
undetectable
5vuzB-3ti8A:
undetectable		 5vuzA-3ti8A:
21.75
5vuzB-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 5vv0A-3ti8A:
undetectable
5vv0B-3ti8A:
undetectable		 5vv0A-3ti8A:
21.43
5vv0B-3ti8A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 5vv0A-3ti8A:
undetectable
5vv0B-3ti8A:
undetectable		 5vv0A-3ti8A:
21.43
5vv0B-3ti8A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 5vv1A-3ti8A:
undetectable
5vv1B-3ti8A:
undetectable		 5vv1A-3ti8A:
21.75
5vv1B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 6 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 5vv1A-3ti8A:
undetectable
5vv1B-3ti8A:
undetectable		 5vv1A-3ti8A:
21.75
5vv1B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 5vv2A-3ti8A:
undetectable
5vv2B-3ti8A:
undetectable		 5vv2A-3ti8A:
21.75
5vv2B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 5vv2A-3ti8A:
undetectable
5vv2B-3ti8A:
undetectable		 5vv2A-3ti8A:
21.75
5vv2B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 5vv3A-3ti8A:
undetectable
5vv3B-3ti8A:
undetectable		 5vv3A-3ti8A:
21.75
5vv3B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 5vv3A-3ti8A:
undetectable
5vv3B-3ti8A:
undetectable		 5vv3A-3ti8A:
21.75
5vv3B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.37A 5vv4A-3ti8A:
undetectable
5vv4B-3ti8A:
undetectable		 5vv4A-3ti8A:
21.75
5vv4B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.38A 5vv5A-3ti8A:
undetectable
5vv5B-3ti8A:
undetectable		 5vv5A-3ti8A:
21.75
5vv5B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 5vv5A-3ti8A:
undetectable
5vv5B-3ti8A:
undetectable		 5vv5A-3ti8A:
21.75
5vv5B-3ti8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 6auqA-3ti8A:
undetectable
6auqB-3ti8A:
undetectable		 6auqA-3ti8A:
10.89
6auqB-3ti8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 6aurA-3ti8A:
undetectable
6aurB-3ti8A:
undetectable		 6aurA-3ti8A:
10.89
6aurB-3ti8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 6aurA-3ti8A:
undetectable
6aurB-3ti8A:
undetectable		 6aurA-3ti8A:
10.89
6aurB-3ti8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 6ausA-3ti8A:
undetectable
6ausB-3ti8A:
undetectable		 6ausA-3ti8A:
10.89
6ausB-3ti8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 6ausA-3ti8A:
undetectable
6ausB-3ti8A:
undetectable		 6ausA-3ti8A:
10.89
6ausB-3ti8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.46A 6autA-3ti8A:
undetectable
6autB-3ti8A:
undetectable		 6autA-3ti8A:
10.89
6autB-3ti8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 6autA-3ti8A:
undetectable
6autB-3ti8A:
undetectable		 6autA-3ti8A:
10.89
6autB-3ti8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 6auuA-3ti8A:
undetectable
6auuB-3ti8A:
undetectable		 6auuA-3ti8A:
10.89
6auuB-3ti8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 6auuA-3ti8A:
undetectable
6auuB-3ti8A:
undetectable		 6auuA-3ti8A:
10.89
6auuB-3ti8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 6auvA-3ti8A:
undetectable
6auvB-3ti8A:
undetectable		 6auvA-3ti8A:
10.89
6auvB-3ti8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.42A 6auvA-3ti8A:
undetectable
6auvB-3ti8A:
undetectable		 6auvA-3ti8A:
10.89
6auvB-3ti8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 6auwA-3ti8A:
undetectable
6auwB-3ti8A:
undetectable		 6auwA-3ti8A:
10.89
6auwB-3ti8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 6auwA-3ti8A:
undetectable
6auwB-3ti8A:
undetectable		 6auwA-3ti8A:
10.89
6auwB-3ti8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.39A 6auxA-3ti8A:
undetectable
6auxB-3ti8A:
undetectable		 6auxA-3ti8A:
10.89
6auxB-3ti8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 6auyA-3ti8A:
undetectable
6auyB-3ti8A:
undetectable		 6auyA-3ti8A:
11.39
6auyB-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 6auyA-3ti8A:
undetectable
6auyB-3ti8A:
undetectable		 6auyA-3ti8A:
11.39
6auyB-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 6auzA-3ti8A:
undetectable
6auzB-3ti8A:
undetectable		 6auzA-3ti8A:
11.39
6auzB-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.39A 6auzA-3ti8A:
undetectable
6auzB-3ti8A:
undetectable		 6auzA-3ti8A:
11.39
6auzB-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 6av0A-3ti8A:
undetectable
6av0B-3ti8A:
undetectable		 6av0A-3ti8A:
11.39
6av0B-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.38A 6av0A-3ti8A:
undetectable
6av0B-3ti8A:
undetectable		 6av0A-3ti8A:
11.39
6av0B-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.35A 6av1A-3ti8A:
undetectable
6av1B-3ti8A:
undetectable		 6av1A-3ti8A:
11.39
6av1B-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.46A 6av2A-3ti8A:
undetectable
6av2B-3ti8A:
undetectable		 6av2A-3ti8A:
11.39
6av2B-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.36A 6av2A-3ti8A:
undetectable
6av2B-3ti8A:
undetectable		 6av2A-3ti8A:
11.39
6av2B-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 6av3A-3ti8A:
undetectable
6av3B-3ti8A:
undetectable		 6av3A-3ti8A:
11.39
6av3B-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 6av3A-3ti8A:
undetectable
6av3B-3ti8A:
undetectable		 6av3A-3ti8A:
11.39
6av3B-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.41A 6av4A-3ti8A:
undetectable
6av4B-3ti8A:
undetectable		 6av4A-3ti8A:
11.39
6av4B-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.41A 6av4A-3ti8A:
undetectable
6av4B-3ti8A:
undetectable		 6av4A-3ti8A:
11.39
6av4B-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.44A 6av5A-3ti8A:
undetectable
6av5B-3ti8A:
undetectable		 6av5A-3ti8A:
11.39
6av5B-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.40A 6av5A-3ti8A:
undetectable
6av5B-3ti8A:
undetectable		 6av5A-3ti8A:
11.39
6av5B-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 434
LYS A 430
ARG A 152
 None
None
LNV  A 901 (-4.0A)
 1.15A 6c06D-3ti8A:
undetectable		 6c06D-3ti8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.42A 6cicA-3ti8A:
undetectable
6cicB-3ti8A:
undetectable		 6cicA-3ti8A:
11.39
6cicB-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.43A 6cicA-3ti8A:
undetectable
6cicB-3ti8A:
undetectable		 6cicA-3ti8A:
11.39
6cicB-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 VAL A 240
TRP A 239
PHE A 305
GLU A 265
 None
 1.43A 6cidA-3ti8A:
undetectable
6cidB-3ti8A:
undetectable		 6cidA-3ti8A:
11.39
6cidB-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		4 / 7 PHE A 305
GLU A 265
VAL A 240
TRP A 239
 None
 1.44A 6cidA-3ti8A:
undetectable
6cidB-3ti8A:
undetectable		 6cidA-3ti8A:
11.39
6cidB-3ti8A:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 118
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 ( 3.8A)
LNV  A 901 (-2.8A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.33A 6ekuA-3ti8A:
12.2		 6ekuA-3ti8A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_0
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
ARG A 292
ARG A 371
TYR A 406
 LNV  A 901 (-3.0A)
LNV  A 901 (-3.6A)
LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.0A)
LNV  A 901 (-4.1A)
LNV  A 901 (-3.4A)
LNV  A 901 (-3.5A)
LNV  A 901 (-2.9A)
LNV  A 901 (-2.8A)
LNV  A 901 (-2.9A)
LNV  A 901 (-4.8A)
 0.26A 6hcxA-3ti8A:
65.0		 6hcxA-3ti8A:
29.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 3ti8 NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 TRP A 178
ILE A 222
GLU A 277
 None
None
LNV  A 901 ( 3.8A)
 0.09A 6hcxA-3ti8A:
65.0		 6hcxA-3ti8A:
29.71