SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tia'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.43A 1a4gA-3tiaA:
55.2		 1a4gA-3tiaA:
28.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_A_ZMRA466_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.14A 1a4gA-3tiaA:
55.2		 1a4gA-3tiaA:
28.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.46A 1a4gB-3tiaA:
55.0		 1a4gB-3tiaA:
28.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ASP A 151
ARG A 152
ILE A 222
 LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
None
 0.18A 1a4gB-3tiaA:
55.2		 1a4gB-3tiaA:
28.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7F_A_BCZA801_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
ARG A 156
ILE A 194
GLU A 277
TYR A 406
 LNV  A 801 (-3.5A)
LNV  A 801 (-4.0A)
None
LNV  A 801 (-3.8A)
LNV  A 801 (-4.4A)
 1.47A 1l7fA-3tiaA:
64.9		 1l7fA-3tiaA:
41.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7F_A_BCZA801_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
TRP A 178
ILE A 222
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-4.0A)
None
None
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.4A)
 0.45A 1l7fA-3tiaA:
64.9		 1l7fA-3tiaA:
41.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
ARG A 152
ARG A 371
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.9A)
LNV  A 801 (-2.9A)
 0.13A 1l7fA-3tiaA:
64.9		 1l7fA-3tiaA:
41.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7G_A_BCZA801_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 LEU A 134
ASP A 151
ARG A 152
ARG A 156
TRP A 178
ILE A 222
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 None
LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.4A)
 0.46A 1l7gA-3tiaA:
64.9		 1l7gA-3tiaA:
41.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7H_A_BCZA801_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
ARG A 156
ILE A 194
GLU A 277
TYR A 406
 LNV  A 801 (-3.5A)
LNV  A 801 (-4.0A)
None
LNV  A 801 (-3.8A)
LNV  A 801 (-4.4A)
 1.48A 1l7hA-3tiaA:
64.8		 1l7hA-3tiaA:
41.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7H_A_BCZA801_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
TRP A 178
ILE A 222
ARG A 224
GLU A 227
GLU A 276
GLU A 277
TYR A 406
 LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-4.0A)
None
None
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-4.4A)
 0.48A 1l7hA-3tiaA:
64.8		 1l7hA-3tiaA:
41.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
ARG A 152
ARG A 371
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.9A)
LNV  A 801 (-2.9A)
 0.12A 1l7hA-3tiaA:
64.8		 1l7hA-3tiaA:
41.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 420
ILE A 233
TRP A  87
 None
 1.12A 1m8eB-3tiaA:
undetectable		 1m8eB-3tiaA:
21.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ARG A 152
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.27A 1nncA-3tiaA:
64.7		 1nncA-3tiaA:
41.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NNC_A_ZMRA479_2
(NEURAMINIDASE N9)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ASP A 151
ARG A 156
TRP A 178
ILE A 222
 LNV  A 801 (-3.4A)
LNV  A 801 (-4.0A)
None
None
 0.11A 1nncA-3tiaA:
64.7		 1nncA-3tiaA:
41.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 THR A 236
VAL A 287
GLY A 286
ILE A 254
 None
 0.81A 2a1mB-3tiaA:
undetectable		 2a1mB-3tiaA:
21.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.19A 2cmlA-3tiaA:
64.9		 2cmlA-3tiaA:
43.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 227
ALA A 246
ARG A 292
ASN A 294
TYR A 406
 LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.4A)
 1.15A 2cmlA-3tiaA:
64.9		 2cmlA-3tiaA:
43.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1477_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.20A 2cmlA-3tiaA:
64.9		 2cmlA-3tiaA:
43.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 7 SER A 367
SER A 370
SER A 372
ASN A 400
TRP A 403
 None
 0.73A 2cmlA-3tiaA:
64.9		 2cmlA-3tiaA:
43.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.19A 2cmlB-3tiaA:
64.8		 2cmlB-3tiaA:
43.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_B_ZMRB2477_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.21A 2cmlB-3tiaA:
64.8		 2cmlB-3tiaA:
43.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 8 SER A 367
SER A 370
SER A 372
ASN A 400
TRP A 403
 None
 0.46A 2cmlB-3tiaA:
64.8		 2cmlB-3tiaA:
43.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.20A 2cmlC-3tiaA:
64.7		 2cmlC-3tiaA:
43.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 227
ALA A 246
ARG A 292
ASN A 294
TYR A 406
 LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.4A)
 1.20A 2cmlC-3tiaA:
64.7		 2cmlC-3tiaA:
43.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3477_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.28A 2cmlC-3tiaA:
64.7		 2cmlC-3tiaA:
43.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 8 SER A 367
SER A 370
SER A 372
ASN A 400
TRP A 403
 None
 0.77A 2cmlC-3tiaA:
64.7		 2cmlC-3tiaA:
43.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.20A 2cmlD-3tiaA:
64.7		 2cmlD-3tiaA:
43.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_D_ZMRD4477_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.24A 2cmlD-3tiaA:
64.7		 2cmlD-3tiaA:
43.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 8 SER A 367
SER A 370
SER A 372
ASN A 400
TRP A 403
 None
 0.65A 2cmlD-3tiaA:
64.7		 2cmlD-3tiaA:
43.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 118
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.41A 2f0zA-3tiaA:
21.6		 2f0zA-3tiaA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 156
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 801 (-4.0A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 1.03A 2f0zA-3tiaA:
21.6		 2f0zA-3tiaA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F10_A_BCZA382_0
(SIALIDASE 2)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 118
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.44A 2f10A-3tiaA:
9.9		 2f10A-3tiaA:
19.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 152
ARG A 156
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.49A 2htqA-3tiaA:
62.8		 2htqA-3tiaA:
41.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTQ_A_ZMRA472_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ASP A 151
TRP A 178
ILE A 222
ARG A 224
 LNV  A 801 (-3.4A)
None
None
LNV  A 801 (-4.2A)
 0.33A 2htqA-3tiaA:
62.8		 2htqA-3tiaA:
41.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTU_A_BCZA801_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
TRP A 178
SER A 179
ILE A 222
ARG A 224
GLU A 276
ARG A 292
TYR A 406
 LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
LNV  A 801 ( 4.7A)
None
LNV  A 801 (-4.2A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.4A)
 0.49A 2htuA-3tiaA:
63.7		 2htuA-3tiaA:
41.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HTU_A_BCZA801_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 118
ASP A 151
GLU A 227
ARG A 371
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.4A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
 0.34A 2htuA-3tiaA:
63.7		 2htuA-3tiaA:
41.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.19A 3b7eA-3tiaA:
64.2		 3b7eA-3tiaA:
40.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_A_ZMRA1001_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.09A 3b7eA-3tiaA:
64.2		 3b7eA-3tiaA:
40.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.18A 3b7eB-3tiaA:
64.2		 3b7eB-3tiaA:
40.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3B7E_B_ZMRB1002_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.09A 3b7eB-3tiaA:
64.2		 3b7eB-3tiaA:
40.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF6_H_SVRH301_1
(THROMBIN, HEAVY
CHAIN)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 11 PRO A 431
ARG A 430
GLN A 347
GLY A 345
GLU A 343
 None
None
None
CA  A 501 (-4.1A)
None
 1.37A 3bf6H-3tiaA:
undetectable		 3bf6H-3tiaA:
19.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		10 / 12 ARG A 118
GLU A 119
ARG A 152
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.9A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.37A 3ckzA-3tiaA:
63.9		 3ckzA-3tiaA:
41.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 6 ASP A 151
ARG A 156
TRP A 178
ILE A 222
ARG A 224
 LNV  A 801 (-3.4A)
LNV  A 801 (-4.0A)
None
None
LNV  A 801 (-4.2A)
 0.67A 3ckzA-3tiaA:
63.9		 3ckzA-3tiaA:
41.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 9 VAL A 287
ARG A 288
ILE A 312
ILE A 257
GLY A 235
 None
 1.19A 3cv9A-3tiaA:
undetectable		 3cv9A-3tiaA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 420
ILE A 233
TRP A  87
 None
 1.09A 3e68A-3tiaA:
undetectable		 3e68A-3tiaA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 420
ILE A 233
TRP A  87
 None
 1.12A 3e6tB-3tiaA:
undetectable		 3e6tB-3tiaA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 156
TRP A 178
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-4.0A)
None
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.4A)
 0.46A 3k37A-3tiaA:
55.2		 3k37A-3tiaA:
29.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ASP A 151
ARG A 152
ARG A 371
 LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-2.9A)
 0.20A 3k37A-3tiaA:
55.2		 3k37A-3tiaA:
29.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 156
TRP A 178
ARG A 224
GLU A 227
ALA A 246
GLU A 277
ARG A 292
ARG A 371
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-4.0A)
None
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-2.9A)
 0.36A 3k37B-3tiaA:
55.1		 3k37B-3tiaA:
29.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
GLU A 276
TYR A 406
 LNV  A 801 (-3.9A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.26A 3k37B-3tiaA:
54.9		 3k37B-3tiaA:
29.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_A_BCZA1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.4A)
 0.59A 3k39A-3tiaA:
54.7		 3k39A-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 277
ARG A 292
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.4A)
 0.51A 3k39B-3tiaA:
54.6		 3k39B-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
 0.59A 3k39C-3tiaA:
54.7		 3k39C-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
 1.47A 3k39C-3tiaA:
54.7		 3k39C-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
 LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-2.9A)
 0.60A 3k39D-3tiaA:
54.5		 3k39D-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_E_BCZE1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.4A)
 0.58A 3k39E-3tiaA:
54.8		 3k39E-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_F_BCZF1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.4A)
 0.57A 3k39F-3tiaA:
54.8		 3k39F-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_G_BCZG1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.4A)
 0.58A 3k39G-3tiaA:
54.8		 3k39G-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.4A)
 0.58A 3k39H-3tiaA:
54.7		 3k39H-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
 0.59A 3k39I-3tiaA:
54.7		 3k39I-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
 1.46A 3k39I-3tiaA:
54.7		 3k39I-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
 0.59A 3k39J-3tiaA:
54.7		 3k39J-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
 1.47A 3k39J-3tiaA:
54.7		 3k39J-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
 0.59A 3k39K-3tiaA:
54.7		 3k39K-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
 1.47A 3k39K-3tiaA:
54.7		 3k39K-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
 0.58A 3k39L-3tiaA:
54.7		 3k39L-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 156
ARG A 371
 LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
 1.47A 3k39L-3tiaA:
54.7		 3k39L-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_M_BCZM1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.4A)
 0.58A 3k39M-3tiaA:
54.7		 3k39M-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.58A 3k39N-3tiaA:
54.7		 3k39N-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.60A 3k39O-3tiaA:
54.8		 3k39O-3tiaA:
29.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.59A 3k39P-3tiaA:
54.7		 3k39P-3tiaA:
29.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.15A 3sanA-3tiaA:
65.1		 3sanA-3tiaA:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_A_ZMRA901_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 ASP A 151
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.11A 3sanA-3tiaA:
65.1		 3sanA-3tiaA:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.16A 3sanB-3tiaA:
65.0		 3sanB-3tiaA:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SAN_B_ZMRB901_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 ASP A 151
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.09A 3sanB-3tiaA:
65.0		 3sanB-3tiaA:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.17A 3ti5A-3tiaA:
64.4		 3ti5A-3tiaA:
42.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_A_ZMRA1002_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.10A 3ti5A-3tiaA:
64.4		 3ti5A-3tiaA:
42.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.17A 3ti5B-3tiaA:
64.4		 3ti5B-3tiaA:
42.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TI5_B_ZMRB1002_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.08A 3ti5B-3tiaA:
64.4		 3ti5B-3tiaA:
42.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
TRP A 178
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
None
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.08A 3ticA-3tiaA:
76.6		 3ticA-3tiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
ILE A 222
ARG A 224
 None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
LNV  A 801 (-4.2A)
 0.06A 3ticA-3tiaA:
76.6		 3ticA-3tiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.09A 3ticB-3tiaA:
76.4		 3ticB-3tiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_B_ZMRB1002_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.04A 3ticB-3tiaA:
76.4		 3ticB-3tiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.09A 3ticC-3tiaA:
76.6		 3ticC-3tiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_C_ZMRC1002_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.04A 3ticC-3tiaA:
76.6		 3ticC-3tiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.08A 3ticD-3tiaA:
76.5		 3ticD-3tiaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TIC_D_ZMRD1002_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 152
ARG A 156
TRP A 178
ILE A 222
 None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.06A 3ticD-3tiaA:
76.5		 3ticD-3tiaA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 10 ILE A 257
PHE A 205
THR A 225
SER A 179
ILE A 194
 None
None
None
LNV  A 801 ( 4.7A)
None
 1.06A 3um5A-3tiaA:
undetectable		 3um5A-3tiaA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UM5_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 10 ILE A 257
PHE A 205
THR A 225
SER A 179
ILE A 194
 None
None
None
LNV  A 801 ( 4.7A)
None
 1.06A 3um5B-3tiaA:
undetectable		 3um5B-3tiaA:
20.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.26A 4b7nA-3tiaA:
64.0		 4b7nA-3tiaA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
 0.08A 4b7nA-3tiaA:
64.0		 4b7nA-3tiaA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.24A 4b7qA-3tiaA:
63.8		 4b7qA-3tiaA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
ILE A 222
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
 0.21A 4b7qA-3tiaA:
63.8		 4b7qA-3tiaA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.28A 4b7qB-3tiaA:
63.8		 4b7qB-3tiaA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_B_ZMRB601_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 LEU A 134
ARG A 152
ARG A 156
TRP A 178
 None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
 0.15A 4b7qB-3tiaA:
63.8		 4b7qB-3tiaA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.28A 4b7qC-3tiaA:
63.7		 4b7qC-3tiaA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 224
GLU A 276
GLU A 277
ARG A 118
TYR A 406
 LNV  A 801 (-4.2A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-2.8A)
LNV  A 801 (-4.4A)
 1.49A 4b7qC-3tiaA:
63.7		 4b7qC-3tiaA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
ILE A 222
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
 0.16A 4b7qC-3tiaA:
63.7		 4b7qC-3tiaA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_D_ZMRD601_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.29A 4b7qD-3tiaA:
63.9		 4b7qD-3tiaA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B7Q_D_ZMRD601_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.27A 4b7qD-3tiaA:
63.9		 4b7qD-3tiaA:
45.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.47A 4cpnA-3tiaA:
55.1		 4cpnA-3tiaA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPN_A_ZMRA700_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ARG A 152
ARG A 156
TRP A 178
ILE A 222
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
 0.12A 4cpnA-3tiaA:
55.1		 4cpnA-3tiaA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.42A 4cpnB-3tiaA:
55.3		 4cpnB-3tiaA:
30.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.48A 4cpzA-3tiaA:
55.1		 4cpzA-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		6 / 12 ARG A 371
ARG A 224
ALA A 246
GLU A 276
GLU A 277
TYR A 406
 LNV  A 801 (-2.9A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-4.4A)
 1.47A 4cpzA-3tiaA:
55.1		 4cpzA-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_A_ZMRA1471_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ASP A 151
ARG A 152
ARG A 156
TRP A 178
 None
LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
 0.13A 4cpzA-3tiaA:
55.1		 4cpzA-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.44A 4cpzB-3tiaA:
14.9		 4cpzB-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_B_ZMRB1471_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ASP A 151
ARG A 152
ARG A 156
TRP A 178
 LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
 0.14A 4cpzB-3tiaA:
15.0		 4cpzB-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.46A 4cpzC-3tiaA:
54.9		 4cpzC-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
 0.18A 4cpzC-3tiaA:
55.1		 4cpzC-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.43A 4cpzD-3tiaA:
55.0		 4cpzD-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_D_ZMRD1471_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 ASP A 151
ARG A 152
ARG A 156
TRP A 178
 LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
 0.14A 4cpzD-3tiaA:
55.0		 4cpzD-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.48A 4cpzE-3tiaA:
55.0		 4cpzE-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
 0.18A 4cpzE-3tiaA:
55.0		 4cpzE-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_F_ZMRF1470_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.49A 4cpzF-3tiaA:
54.9		 4cpzF-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
 0.10A 4cpzF-3tiaA:
54.9		 4cpzF-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.45A 4cpzG-3tiaA:
54.8		 4cpzG-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
 0.13A 4cpzG-3tiaA:
54.8		 4cpzG-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_H_ZMRH1470_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.50A 4cpzH-3tiaA:
54.9		 4cpzH-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
ARG A 156
TRP A 178
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
 0.18A 4cpzH-3tiaA:
54.9		 4cpzH-3tiaA:
30.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I00_A_ZMRA509_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 152
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.41A 4i00A-3tiaA:
65.4		 4i00A-3tiaA:
45.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ARG A 156
TRP A 178
ILE A 222
ASN A 294
 None
LNV  A 801 (-4.0A)
None
None
LNV  A 801 (-4.0A)
 0.87A 4i00A-3tiaA:
65.4		 4i00A-3tiaA:
45.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 8 SER A 228
SER A 279
TYR A 423
TRP A 352
 None
 1.14A 4ms4A-3tiaA:
undetectable		 4ms4A-3tiaA:
22.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.14A 4mwrA-3tiaA:
64.8		 4mwrA-3tiaA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 LEU A 134
ASP A 151
ARG A 152
TRP A 178
ILE A 222
 None
LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
None
None
 0.11A 4mwrA-3tiaA:
64.8		 4mwrA-3tiaA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ASP A 151
ARG A 152
ILE A 222
ARG A 224
GLU A 227
 LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
None
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
 1.30A 4mwvA-3tiaA:
64.8		 4mwvA-3tiaA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 GLU A 119
ARG A 156
ILE A 194
GLU A 277
TYR A 406
 LNV  A 801 (-3.5A)
LNV  A 801 (-4.0A)
None
LNV  A 801 (-3.8A)
LNV  A 801 (-4.4A)
 1.45A 4mwvA-3tiaA:
64.8		 4mwvA-3tiaA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWV_A_BCZA513_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 GLU A 119
LEU A 134
ASP A 151
ARG A 152
ARG A 156
TRP A 178
ILE A 222
ARG A 224
GLU A 276
GLU A 277
ARG A 292
TYR A 406
 LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
LNV  A 801 (-4.2A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.4A)
 0.43A 4mwvA-3tiaA:
64.8		 4mwvA-3tiaA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
GLU A 227
ARG A 371
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-2.9A)
 0.12A 4mwvA-3tiaA:
64.8		 4mwvA-3tiaA:
42.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.23A 4mwxA-3tiaA:
64.7		 4mwxA-3tiaA:
42.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 152
TRP A 178
ILE A 222
 LNV  A 801 (-3.9A)
None
None
 0.09A 4mwxA-3tiaA:
64.7		 4mwxA-3tiaA:
42.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MX0_A_BCZA513_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 GLU A 119
LEU A 134
ARG A 152
ARG A 156
TRP A 178
SER A 179
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
TYR A 406
 LNV  A 801 (-3.5A)
None
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
LNV  A 801 ( 4.7A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-4.4A)
 0.46A 4mx0A-3tiaA:
64.6		 4mx0A-3tiaA:
42.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 ARG A 118
ASP A 151
ARG A 371
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
 0.16A 4mx0A-3tiaA:
64.6		 4mx0A-3tiaA:
42.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QE6_A_JN3A1001_1
(BILE ACID RECEPTOR)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ALA A 203
MET A 241
ARG A 253
ILE A 265
ILE A 257
 None
 1.21A 4qe6A-3tiaA:
undetectable		 4qe6A-3tiaA:
19.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		11 / 12 ARG A 118
GLU A 119
ASP A 151
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ASN A 294
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-4.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.52A 4wa5A-3tiaA:
63.0		 4wa5A-3tiaA:
42.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA5_A_ZMRA501_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 5 ARG A 152
ARG A 156
TRP A 178
ILE A 222
ARG A 224
 LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
None
None
LNV  A 801 (-4.2A)
 0.52A 4wa5A-3tiaA:
63.0		 4wa5A-3tiaA:
42.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L17_A_ZMRA512_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.23A 5l17A-3tiaA:
64.9		 5l17A-3tiaA:
44.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L17_A_ZMRA512_2
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		4 / 4 LEU A 134
ARG A 152
TRP A 178
ILE A 222
 None
LNV  A 801 (-3.9A)
None
None
 0.13A 5l17A-3tiaA:
64.9		 5l17A-3tiaA:
44.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_A_STIA302_1
(DEOXYCYTIDINE KINASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 VAL A 398
GLU A 277
PHE A 422
SER A 279
GLU A 375
 None
LNV  A 801 (-3.8A)
None
None
None
 1.46A 5mqtA-3tiaA:
undetectable		 5mqtA-3tiaA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		5 / 12 ARG A 118
GLU A 277
ARG A 292
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.8A)
LNV  A 801 (-3.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.34A 6ekuA-3tiaA:
5.7		 6ekuA-3tiaA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_0
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		12 / 12 ARG A 118
GLU A 119
ASP A 151
ARG A 152
ARG A 156
ARG A 224
GLU A 227
ALA A 246
GLU A 276
ARG A 292
ARG A 371
TYR A 406
 LNV  A 801 (-2.8A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-4.0A)
LNV  A 801 (-4.2A)
LNV  A 801 (-3.5A)
LNV  A 801 (-3.4A)
LNV  A 801 (-2.9A)
LNV  A 801 (-3.0A)
LNV  A 801 (-2.9A)
LNV  A 801 (-4.4A)
 0.19A 6hcxA-3tiaA:
19.0		 6hcxA-3tiaA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 3tia NEURAMINIDASE
(Influenza
A
virus) 		3 / 3 TRP A 178
ILE A 222
GLU A 277
 None
None
LNV  A 801 (-3.8A)
 0.08A 6hcxA-3tiaA:
19.0		 6hcxA-3tiaA:
10.26