SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tig'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QEL_D_QELD2_1 (NMDA GLUTAMATE RECEPTOR SUBUNIT GLUTAMATE [NMDA] RECEPTOR SUBUNIT EPSILON-2)	3tig	TTL PROTEIN (Xenopus tropicalis)	4 / 5	TYR A 2 THR A 3 PHE A 4 LEU A 61	None	0.74A	3qelC-3tigA: undetectable	3qelC-3tigA: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IWU_A_ACTA402_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	3tig	TTL PROTEIN (Xenopus tropicalis)	4 / 6	PHE A 315 VAL A 207 TYR A 211 ILE A 302	None	1.29A	5iwuA-3tigA: undetectable	5iwuA-3tigA: 20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OG9_B_TESB502_1 (-)	3tig	TTL PROTEIN (Xenopus tropicalis)	5 / 12	LEU A 39 VAL A 6 LEU A 41 ILE A 20 ALA A 15	None None MG A 379 (-4.3A) None None	1.15A	5og9B-3tigA: undetectable	5og9B-3tigA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UC3_A_486A801_2 (GLUCOCORTICOID RECEPTOR)	3tig	TTL PROTEIN (Xenopus tropicalis)	4 / 5	LEU A 71 LEU A 77 GLN A 313 TYR A 64	None None None MG A 378 ( 4.6A)	1.20A	5uc3A-3tigA: undetectable	5uc3A-3tigA: 12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VEU_H_RITH602_2 (CYTOCHROME P450 3A5)	3tig	TTL PROTEIN (Xenopus tropicalis)	4 / 5	PHE A 263 PHE A 264 LEU A 221 LEU A 346	None	1.26A	5veuH-3tigA: undetectable	5veuH-3tigA: 20.62

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3QEL_D_QELD2_1","NMDA GLUTAMATE RECEPTOR SUBUNIT;GLUTAMATE [NMDA] RECEPTOR SUBUNIT EPSILON-2","3tig","TTL PROTEIN","Xenopus tropicalis",4,"TYR A   2;THR A   3;PHE A   4;LEU A  61","None","0.74A","3qelC-3tigA:undetectable","3qelC-3tigA:21.30"],["5IWU_A_ACTA402_0","MACROLIDE 2'-PHOSPHOTRANSFERASE II","3tig","TTL PROTEIN","Xenopus tropicalis",4,"PHE A 315;VAL A 207;TYR A 211;ILE A 302","None","1.29A","5iwuA-3tigA:undetectable","5iwuA-3tigA:20.36"],["5OG9_B_TESB502_1","-","3tig","TTL PROTEIN","Xenopus tropicalis",5,"LEU A  39;VAL A   6;LEU A  41;ILE A  20;ALA A  15","None;None; MG A 379 (-4.3A);None;None","1.15A","5og9B-3tigA:undetectable","5og9B-3tigA:22.22"],["5UC3_A_486A801_2","GLUCOCORTICOID RECEPTOR","3tig","TTL PROTEIN","Xenopus tropicalis",4,"LEU A  71;LEU A  77;GLN A 313;TYR A  64","None;None;None; MG A 378 ( 4.6A)","1.20A","5uc3A-3tigA:undetectable","5uc3A-3tigA:12.26"],["5VEU_H_RITH602_2","CYTOCHROME P450 3A5","3tig","TTL PROTEIN","Xenopus tropicalis",4,"PHE A 263;PHE A 264;LEU A 221;LEU A 346","None","1.26A","5veuH-3tigA:undetectable","5veuH-3tigA:20.62"]]