SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		4 / 5 ALA A 205
TYR A 201
ALA A 408
GLN A  53
 None
 1.13A 1xl6A-3tijA:
undetectable
1xl6B-3tijA:
undetectable		 1xl6A-3tijA:
21.04
1xl6B-3tijA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 LEU A 406
LEU A 403
ALA A 400
ILE A 399
ALA A 367
 None
None
None
DMU  A 424 ( 4.7A)
None
 1.24A 2bxpA-3tijA:
undetectable		 2bxpA-3tijA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 10 LEU A 379
GLY A 377
LEU A 376
LEU A 375
ILE A 372
 None
None
None
None
DMU  A 420 (-3.9A)
 1.02A 2f8dA-3tijA:
undetectable		 2f8dA-3tijA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		4 / 8 ARG A 392
PRO A 227
SER A 139
MET A 168
 None
 1.14A 2qd2A-3tijA:
undetectable		 2qd2A-3tijA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		4 / 5 PHE A  97
PHE A 270
PHE A 333
ILE A 277
 None
DMU  A 422 ( 4.1A)
URI  A 419 (-4.9A)
None
 1.37A 2v0mD-3tijA:
undetectable		 2v0mD-3tijA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		4 / 8 LEU A 376
ARG A 387
GLY A 388
ALA A 391
 None
None
None
DMU  A 420 (-4.9A)
 0.89A 2xfsA-3tijA:
undetectable		 2xfsA-3tijA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		4 / 8 LEU A 376
ARG A 387
GLY A 388
ALA A 391
 None
None
None
DMU  A 420 (-4.9A)
 0.90A 2xh9A-3tijA:
undetectable		 2xh9A-3tijA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		6 / 12 GLY A 180
GLY A 179
ALA A 209
PRO A 158
ALA A 157
ALA A 367
 NA  A 421 ( 4.6A)
None
None
None
None
None
 1.45A 3jb2A-3tijA:
undetectable		 3jb2A-3tijA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_G_TFPG201_1
(PROTEIN S100-A4)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 9 GLY A 401
PHE A 216
GLY A 365
ILE A 310
PHE A  36
 None
 1.49A 3ko0F-3tijA:
undetectable
3ko0G-3tijA:
0.4		 3ko0F-3tijA:
16.43
3ko0G-3tijA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 GLU A 142
GLY A 213
ALA A 175
SER A 145
ALA A 209
 None
 1.34A 3nmuA-3tijA:
undetectable
3nmuF-3tijA:
undetectable		 3nmuA-3tijA:
24.89
3nmuF-3tijA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		4 / 5 TYR A  48
ILE A 199
LEU A 202
LYS A 198
 None
 1.27A 3sueC-3tijA:
undetectable		 3sueC-3tijA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 GLY A 137
LEU A 128
GLY A 131
ALA A 146
ALA A 147
 None
DMU  A 425 ( 4.5A)
DMU  A 425 ( 4.3A)
None
None
 1.02A 3sufA-3tijA:
undetectable		 3sufA-3tijA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		4 / 8 PHE A 216
ALA A 182
ASN A 405
ALA A 408
 None
 0.96A 3t3sE-3tijA:
undetectable		 3t3sE-3tijA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		4 / 6 GLU A 223
GLU A 142
GLU A 172
SER A 139
 None
 1.39A 4kr3A-3tijA:
undetectable		 4kr3A-3tijA:
21.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 ALA A 185
LEU A 105
ASN A 331
GLU A 332
PHE A 366
 URI  A 419 ( 3.8A)
None
URI  A 419 ( 4.0A)
URI  A 419 (-3.0A)
URI  A 419 (-3.9A)
 1.03A 4pb1A-3tijA:
72.1		 4pb1A-3tijA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		12 / 12 GLY A 153
GLN A 154
GLU A 156
ALA A 185
TYR A 192
LEU A 259
ASN A 331
GLU A 332
PHE A 366
ASN A 368
SER A 371
ILE A 374
 NA  A 421 ( 3.9A)
URI  A 419 (-3.9A)
URI  A 419 ( 4.3A)
URI  A 419 ( 3.8A)
None
URI  A 419 ( 4.9A)
URI  A 419 ( 4.0A)
URI  A 419 (-3.0A)
URI  A 419 (-3.9A)
URI  A 419 (-3.7A)
URI  A 419 (-2.6A)
URI  A 419 (-4.0A)
 0.17A 4pb1A-3tijA:
72.1		 4pb1A-3tijA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 ALA A 185
LEU A 105
ASN A 331
GLU A 332
PHE A 366
 URI  A 419 ( 3.8A)
None
URI  A 419 ( 4.0A)
URI  A 419 (-3.0A)
URI  A 419 (-3.9A)
 1.05A 4pd5A-3tijA:
71.1		 4pd5A-3tijA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 GLY A 153
ALA A 185
VAL A 188
TYR A 192
ASN A 405
 NA  A 421 ( 3.9A)
URI  A 419 ( 3.8A)
None
None
None
 1.21A 4pd5A-3tijA:
71.1		 4pd5A-3tijA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		12 / 12 GLY A 153
GLN A 154
ALA A 185
VAL A 188
TYR A 192
LEU A 259
ASN A 331
GLU A 332
PHE A 366
ASN A 368
SER A 371
ILE A 374
 NA  A 421 ( 3.9A)
URI  A 419 (-3.9A)
URI  A 419 ( 3.8A)
None
None
URI  A 419 ( 4.9A)
URI  A 419 ( 4.0A)
URI  A 419 (-3.0A)
URI  A 419 (-3.9A)
URI  A 419 (-3.7A)
URI  A 419 (-2.6A)
URI  A 419 (-4.0A)
 0.28A 4pd5A-3tijA:
71.1		 4pd5A-3tijA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 GLY A 153
ALA A 185
VAL A 188
TYR A 192
ASN A 405
 NA  A 421 ( 3.9A)
URI  A 419 ( 3.8A)
None
None
None
 1.22A 4pd9A-3tijA:
71.3		 4pd9A-3tijA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		12 / 12 GLY A 153
GLN A 154
GLU A 156
ALA A 185
VAL A 188
TYR A 192
LEU A 259
GLU A 332
PHE A 366
ASN A 368
SER A 371
ILE A 374
 NA  A 421 ( 3.9A)
URI  A 419 (-3.9A)
URI  A 419 ( 4.3A)
URI  A 419 ( 3.8A)
None
None
URI  A 419 ( 4.9A)
URI  A 419 (-3.0A)
URI  A 419 (-3.9A)
URI  A 419 (-3.7A)
URI  A 419 (-2.6A)
URI  A 419 (-4.0A)
 0.24A 4pd9A-3tijA:
71.3		 4pd9A-3tijA:
99.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		3 / 3 THR A 155
ASN A 331
PHE A 333
 None
URI  A 419 ( 4.0A)
URI  A 419 (-4.9A)
 0.16A 4pd9A-3tijA:
71.3		 4pd9A-3tijA:
99.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		4 / 5 GLU A 172
ALA A 175
GLU A 142
GLU A 223
 None
 1.49A 5dwkC-3tijA:
2.3		 5dwkC-3tijA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 11 VAL A 334
MET A 266
SER A 337
MET A 195
GLY A 191
 None
 1.11A 5g6sA-3tijA:
undetectable
5g6sG-3tijA:
0.9		 5g6sA-3tijA:
24.01
5g6sG-3tijA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 11 VAL A 334
MET A 266
SER A 337
MET A 195
GLY A 191
 None
 1.09A 5g6sB-3tijA:
undetectable
5g6sC-3tijA:
undetectable		 5g6sB-3tijA:
24.01
5g6sC-3tijA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 MET A 266
SER A 337
MET A 195
GLY A 191
VAL A 334
 None
 1.11A 5g6sB-3tijA:
undetectable
5g6sC-3tijA:
undetectable		 5g6sB-3tijA:
24.01
5g6sC-3tijA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 10 VAL A 334
MET A 266
SER A 337
MET A 195
GLY A 191
 None
 1.11A 5g6sD-3tijA:
0.0
5g6sF-3tijA:
1.0		 5g6sD-3tijA:
24.01
5g6sF-3tijA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 11 VAL A 334
MET A 266
SER A 337
MET A 195
GLY A 191
 None
 1.11A 5g6sE-3tijA:
1.0
5g6sH-3tijA:
0.9		 5g6sE-3tijA:
24.01
5g6sH-3tijA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_H_RAUH400_1
(IMINE REDUCTASE)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 10 MET A 266
SER A 337
MET A 195
GLY A 191
VAL A 334
 None
 1.10A 5g6sE-3tijA:
0.9
5g6sH-3tijA:
0.9		 5g6sE-3tijA:
24.01
5g6sH-3tijA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		6 / 9 LEU A 382
VAL A 160
LEU A 159
MET A 168
LEU A 173
ALA A 148
 None
 1.27A 5og9A-3tijA:
undetectable		 5og9A-3tijA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 12 GLY A 137
ILE A 125
LEU A 128
GLY A 131
ALA A 146
 None
None
DMU  A 425 ( 4.5A)
DMU  A 425 ( 4.3A)
None
 1.04A 6c2mA-3tijA:
undetectable		 6c2mA-3tijA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		3 / 3 LEU A  77
SER A  75
PHE A  76
 None
 0.63A 6fgcA-3tijA:
undetectable		 6fgcA-3tijA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 11 PHE A 151
VAL A 124
MET A 121
ILE A 199
VAL A  63
 None
 1.42A 6hcoA-3tijA:
1.2
6hcoB-3tijA:
undetectable		 6hcoA-3tijA:
23.29
6hcoB-3tijA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 3tij NUPC FAMILY PROTEIN
(Vibrio
cholerae) 		5 / 11 VAL A  63
PHE A 151
ILE A 127
VAL A 124
MET A 121
 None
 1.38A 6hcoA-3tijA:
1.2
6hcoB-3tijA:
undetectable		 6hcoA-3tijA:
23.29
6hcoB-3tijA:
23.29