SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tix'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 THR B 623
ASN B 604
THR B 569
GLY B 606
 None
 1.03A 1bu5A-3tixB:
3.8		 1bu5A-3tixB:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU B 818
LEU B 907
VAL B 816
SER B 815
VAL B 854
 None
 1.11A 1db1A-3tixB:
undetectable		 1db1A-3tixB:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F86_A_T44A428_1
(TRANSTHYRETIN
THR119MET VARIANT)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 4 LYS B 761
LEU B 757
ALA B 760
LEU B 754
 None
 1.39A 1f86A-3tixB:
undetectable		 1f86A-3tixB:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU B 818
LEU B 907
VAL B 816
SER B 815
VAL B 854
 None
 1.09A 1ie9A-3tixB:
undetectable		 1ie9A-3tixB:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.23A 1k2rA-3tixB:
undetectable
1k2rB-3tixB:
undetectable		 1k2rA-3tixB:
22.55
1k2rB-3tixB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 6 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.24A 1k2sA-3tixB:
undetectable
1k2sB-3tixB:
undetectable		 1k2sA-3tixB:
22.55
1k2sB-3tixB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 6 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.22A 1k2uA-3tixB:
undetectable
1k2uB-3tixB:
undetectable		 1k2uA-3tixB:
22.55
1k2uB-3tixB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.33A 1lzxA-3tixB:
undetectable
1lzxB-3tixB:
undetectable		 1lzxA-3tixB:
22.55
1lzxB-3tixB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.29A 1lzxA-3tixB:
undetectable
1lzxB-3tixB:
undetectable		 1lzxA-3tixB:
22.55
1lzxB-3tixB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.29A 1lzzA-3tixB:
undetectable
1lzzB-3tixB:
undetectable		 1lzzA-3tixB:
22.55
1lzzB-3tixB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3
(Saccharomyces
cerevisiae;
Schizosaccharomy
ces
pombe) 		4 / 8 SER B 706
ASN B 744
GLU A  63
GLY A -33
 None
 0.92A 1meiA-3tixB:
undetectable		 1meiA-3tixB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.30A 1mmvA-3tixB:
undetectable
1mmvB-3tixB:
undetectable		 1mmvA-3tixB:
22.55
1mmvB-3tixB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.33A 1mmwA-3tixB:
undetectable
1mmwB-3tixB:
undetectable		 1mmwA-3tixB:
22.55
1mmwB-3tixB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.30A 1mmwA-3tixB:
undetectable
1mmwB-3tixB:
undetectable		 1mmwA-3tixB:
22.55
1mmwB-3tixB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 6 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.30A 1p6hA-3tixB:
undetectable
1p6hB-3tixB:
undetectable		 1p6hA-3tixB:
21.73
1p6hB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.26A 1p6hA-3tixB:
undetectable
1p6hB-3tixB:
undetectable		 1p6hA-3tixB:
21.73
1p6hB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.29A 1p6iA-3tixB:
undetectable
1p6iB-3tixB:
undetectable		 1p6iA-3tixB:
21.73
1p6iB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.31A 1p6kA-3tixB:
undetectable
1p6kB-3tixB:
undetectable		 1p6kA-3tixB:
22.16
1p6kB-3tixB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		5 / 9 LEU B 941
VAL B 813
ILE B 845
TYR B 892
ILE B 897
 None
 1.42A 1q6iA-3tixB:
undetectable		 1q6iA-3tixB:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 8 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.28A 1rs6A-3tixB:
undetectable
1rs6B-3tixB:
undetectable		 1rs6A-3tixB:
21.73
1rs6B-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3
(Saccharomyces
cerevisiae;
Schizosaccharomy
ces
pombe) 		5 / 10 LEU A  51
ARG A  58
ALA A  65
ALA A  62
GLU B 708
 None
None
CL  A1002 ( 4.3A)
None
None
 1.24A 1wygA-3tixA:
2.2		 1wygA-3tixA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3
(Saccharomyces
cerevisiae;
Schizosaccharomy
ces
pombe) 		4 / 8 TYR B 803
ARG A  69
ALA A  62
LEU B 774
 CL  A1002 (-4.9A)
CL  A1002 ( 3.3A)
None
None
 1.01A 1x8vA-3tixB:
undetectable		 1x8vA-3tixB:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 4 LEU B 828
SER B 815
LEU B 881
LEU B 877
 None
 1.14A 1yajA-3tixB:
undetectable		 1yajA-3tixB:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.23A 1zvlA-3tixB:
undetectable
1zvlB-3tixB:
1.2		 1zvlA-3tixB:
21.57
1zvlB-3tixB:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.32A 1zzqA-3tixB:
undetectable
1zzqB-3tixB:
undetectable		 1zzqA-3tixB:
22.98
1zzqB-3tixB:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 8 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.31A 2g6hA-3tixB:
undetectable
2g6hB-3tixB:
undetectable		 2g6hA-3tixB:
22.55
2g6hB-3tixB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 6 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.28A 2g6hA-3tixB:
undetectable
2g6hB-3tixB:
undetectable		 2g6hA-3tixB:
22.55
2g6hB-3tixB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.31A 2g6kA-3tixB:
undetectable
2g6kB-3tixB:
undetectable		 2g6kA-3tixB:
22.55
2g6kB-3tixB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.31A 2g6mA-3tixB:
undetectable
2g6mB-3tixB:
undetectable		 2g6mA-3tixB:
22.55
2g6mB-3tixB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.31A 2g6mA-3tixB:
undetectable
2g6mB-3tixB:
undetectable		 2g6mA-3tixB:
22.55
2g6mB-3tixB:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.26A 2hx4A-3tixB:
undetectable
2hx4B-3tixB:
undetectable		 2hx4A-3tixB:
21.73
2hx4B-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 5 LEU B 603
ASP B 625
LEU B 524
HIS B 598
 None
 1.26A 2jfaA-3tixB:
undetectable		 2jfaA-3tixB:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 5 LEU B 603
ASP B 625
LEU B 524
HIS B 598
 None
 1.29A 2qxsA-3tixB:
undetectable		 2qxsA-3tixB:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 5 LEU B 603
ASP B 625
LEU B 524
HIS B 598
 None
 1.26A 2qxsB-3tixB:
undetectable		 2qxsB-3tixB:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_A_T44A128_1
(TRANSTHYRETIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 4 LYS B 761
LEU B 757
ALA B 760
LEU B 754
 None
 1.44A 2roxA-3tixB:
undetectable		 2roxA-3tixB:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 734
LEU B 757
ALA B 760
PHE B 767
 None
 0.57A 2vcvA-3tixB:
undetectable		 2vcvA-3tixB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		5 / 9 PHE B 734
LEU B 743
LEU B 757
ALA B 760
PHE B 767
 None
 1.09A 2vcvD-3tixB:
undetectable		 2vcvD-3tixB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		5 / 9 PHE B 734
LEU B 743
LEU B 757
ALA B 760
PHE B 767
 None
 1.04A 2vcvE-3tixB:
undetectable		 2vcvE-3tixB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		5 / 9 PHE B 734
LEU B 743
LEU B 757
ALA B 760
PHE B 767
 None
 1.09A 2vcvH-3tixB:
undetectable		 2vcvH-3tixB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		5 / 9 PHE B 734
LEU B 743
LEU B 757
ALA B 760
PHE B 767
 None
 1.03A 2vcvI-3tixB:
undetectable		 2vcvI-3tixB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 734
LEU B 757
ALA B 760
PHE B 767
 None
 0.66A 2vcvL-3tixB:
undetectable		 2vcvL-3tixB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 8 PHE B 734
LEU B 757
ALA B 760
PHE B 767
 None
 0.67A 2vcvP-3tixB:
undetectable		 2vcvP-3tixB:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 8 THR B 817
ILE B 943
ASP B 904
SER B 819
 None
 1.13A 2xytE-3tixB:
undetectable		 2xytE-3tixB:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 THR B 817
ILE B 943
ASP B 904
SER B 819
 None
 1.16A 2xytI-3tixB:
undetectable		 2xytI-3tixB:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.35A 3b3mA-3tixB:
undetectable
3b3mB-3tixB:
undetectable		 3b3mA-3tixB:
21.73
3b3mB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.30A 3b3mA-3tixB:
undetectable
3b3mB-3tixB:
undetectable		 3b3mA-3tixB:
21.73
3b3mB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 8 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.24A 3b3pA-3tixB:
undetectable
3b3pB-3tixB:
undetectable		 3b3pA-3tixB:
21.73
3b3pB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3
(Saccharomyces
cerevisiae;
Schizosaccharomy
ces
pombe) 		4 / 7 VAL A  66
ILE A   6
GLY A   7
LEU B 655
 None
CL  A1003 (-4.1A)
None
None
 0.68A 3bjwB-3tixA:
undetectable		 3bjwB-3tixA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3
(Saccharomyces
cerevisiae;
Schizosaccharomy
ces
pombe) 		4 / 7 VAL A  66
ILE A   6
GLY A   7
LEU B 655
 None
CL  A1003 (-4.1A)
None
None
 0.67A 3bjwF-3tixA:
undetectable		 3bjwF-3tixA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3
(Saccharomyces
cerevisiae;
Schizosaccharomy
ces
pombe) 		4 / 7 VAL A  66
ILE A   6
GLY A   7
LEU B 655
 None
CL  A1003 (-4.1A)
None
None
 0.69A 3bjwH-3tixA:
undetectable		 3bjwH-3tixA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		5 / 12 ILE B 822
LEU B 907
SER B 856
LYS B 855
LEU B 877
 None
 1.16A 3cd2A-3tixB:
undetectable		 3cd2A-3tixB:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.25A 3fc5A-3tixB:
undetectable
3fc5B-3tixB:
undetectable		 3fc5A-3tixB:
21.73
3fc5B-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.25A 3fc5A-3tixB:
undetectable
3fc5B-3tixB:
undetectable		 3fc5A-3tixB:
21.73
3fc5B-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.31A 3hsnA-3tixB:
undetectable
3hsnB-3tixB:
undetectable		 3hsnA-3tixB:
21.73
3hsnB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.33A 3hsoA-3tixB:
undetectable
3hsoB-3tixB:
undetectable		 3hsoA-3tixB:
21.73
3hsoB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.31A 3hspA-3tixB:
undetectable
3hspB-3tixB:
undetectable		 3hspA-3tixB:
21.73
3hspB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.26A 3jt6A-3tixB:
undetectable
3jt6B-3tixB:
undetectable		 3jt6A-3tixB:
21.73
3jt6B-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.31A 3jwtA-3tixB:
undetectable
3jwtB-3tixB:
undetectable		 3jwtA-3tixB:
21.53
3jwtB-3tixB:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.26A 3jx0A-3tixB:
0.9
3jx0B-3tixB:
undetectable		 3jx0A-3tixB:
22.16
3jx0B-3tixB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 8 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.26A 3jx1A-3tixB:
undetectable
3jx1B-3tixB:
undetectable		 3jx1A-3tixB:
22.16
3jx1B-3tixB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU B 818
LEU B 907
VAL B 816
SER B 815
VAL B 854
 None
 1.32A 3m7rA-3tixB:
undetectable		 3m7rA-3tixB:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.28A 3nlpA-3tixB:
undetectable
3nlpB-3tixB:
undetectable		 3nlpA-3tixB:
22.16
3nlpB-3tixB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 8 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.27A 3nlyA-3tixB:
undetectable
3nlyB-3tixB:
undetectable		 3nlyA-3tixB:
21.73
3nlyB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.30A 3nlzA-3tixB:
undetectable
3nlzB-3tixB:
undetectable		 3nlzA-3tixB:
21.73
3nlzB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 5 PHE B 767
ILE B 698
ASN B 939
PHE B 740
 None
 1.33A 3octA-3tixB:
undetectable		 3octA-3tixB:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.28A 3pngA-3tixB:
undetectable
3pngB-3tixB:
undetectable		 3pngA-3tixB:
21.73
3pngB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.35A 3q9aA-3tixB:
undetectable
3q9aB-3tixB:
undetectable		 3q9aA-3tixB:
21.73
3q9aB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.25A 3tymA-3tixB:
undetectable
3tymB-3tixB:
undetectable		 3tymA-3tixB:
21.73
3tymB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.32A 3ufuA-3tixB:
undetectable
3ufuB-3tixB:
undetectable		 3ufuA-3tixB:
21.73
3ufuB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.29A 3ufvA-3tixB:
undetectable
3ufvB-3tixB:
undetectable		 3ufvA-3tixB:
21.73
3ufvB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.31A 4canA-3tixB:
undetectable
4canB-3tixB:
undetectable		 4canA-3tixB:
21.73
4canB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.36A 4capA-3tixB:
undetectable
4capB-3tixB:
undetectable		 4capA-3tixB:
21.73
4capB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.24A 4ctuA-3tixB:
undetectable
4ctuB-3tixB:
undetectable		 4ctuA-3tixB:
21.73
4ctuB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.35A 4ctwA-3tixB:
undetectable
4ctwB-3tixB:
undetectable		 4ctwA-3tixB:
21.73
4ctwB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.32A 4d1nC-3tixB:
undetectable
4d1nD-3tixB:
undetectable		 4d1nC-3tixB:
21.16
4d1nD-3tixB:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.30A 4d2yA-3tixB:
undetectable
4d2yB-3tixB:
undetectable		 4d2yA-3tixB:
21.73
4d2yB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.28A 4d2yA-3tixB:
undetectable
4d2yB-3tixB:
undetectable		 4d2yA-3tixB:
21.73
4d2yB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.25A 4d30A-3tixB:
undetectable
4d30B-3tixB:
undetectable		 4d30A-3tixB:
21.73
4d30B-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.29A 4d3bA-3tixB:
undetectable
4d3bB-3tixB:
undetectable		 4d3bA-3tixB:
21.73
4d3bB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.27A 4fvzA-3tixB:
undetectable
4fvzB-3tixB:
undetectable		 4fvzA-3tixB:
21.73
4fvzB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 3tix UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3
CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe;
Saccharomyces
cerevisiae;
Schizosaccharomy
ces
pombe) 		4 / 7 ALA B 660
SER B 659
VAL A  39
ARG A  38
 None
 1.14A 4ijiH-3tixB:
undetectable		 4ijiH-3tixB:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.29A 4jsfA-3tixB:
undetectable
4jsfB-3tixB:
undetectable		 4jsfA-3tixB:
21.73
4jsfB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 8 ASP B 539
SER B 541
SER B 517
ARG B 521
 None
 1.01A 4lv9A-3tixB:
undetectable
4lv9B-3tixB:
undetectable		 4lv9A-3tixB:
25.23
4lv9B-3tixB:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ASP B 539
SER B 541
SER B 517
ARG B 521
 None
 1.00A 4lv9A-3tixB:
undetectable
4lv9B-3tixB:
undetectable		 4lv9A-3tixB:
25.23
4lv9B-3tixB:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.27A 4uchA-3tixB:
undetectable
4uchB-3tixB:
undetectable		 4uchA-3tixB:
21.31
4uchB-3tixB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.26A 4uh3A-3tixB:
undetectable
4uh3B-3tixB:
undetectable		 4uh3A-3tixB:
21.73
4uh3B-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.34A 4uh5A-3tixB:
undetectable
4uh5B-3tixB:
undetectable		 4uh5A-3tixB:
21.31
4uh5B-3tixB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.31A 4uh6A-3tixB:
undetectable
4uh6B-3tixB:
undetectable		 4uh6A-3tixB:
21.31
4uh6B-3tixB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.26A 4v3uA-3tixB:
undetectable
4v3uB-3tixB:
undetectable		 4v3uA-3tixB:
21.16
4v3uB-3tixB:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.33A 4v3uA-3tixB:
undetectable
4v3uB-3tixB:
undetectable		 4v3uA-3tixB:
21.16
4v3uB-3tixB:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.28A 4v3uC-3tixB:
undetectable
4v3uD-3tixB:
undetectable		 4v3uC-3tixB:
21.16
4v3uD-3tixB:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.24A 4v3uC-3tixB:
undetectable
4v3uD-3tixB:
undetectable		 4v3uC-3tixB:
21.16
4v3uD-3tixB:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.29A 4v3wA-3tixB:
undetectable
4v3wB-3tixB:
undetectable		 4v3wA-3tixB:
21.73
4v3wB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.25A 4v3xA-3tixB:
undetectable
4v3xB-3tixB:
undetectable		 4v3xA-3tixB:
21.73
4v3xB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 6 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.27A 4v3zA-3tixB:
undetectable
4v3zB-3tixB:
undetectable		 4v3zA-3tixB:
21.73
4v3zB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.21A 4v3zA-3tixB:
undetectable
4v3zB-3tixB:
undetectable		 4v3zA-3tixB:
21.73
4v3zB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 6 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.23A 5adbA-3tixB:
undetectable
5adbB-3tixB:
undetectable		 5adbA-3tixB:
21.73
5adbB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.28A 5adcA-3tixB:
undetectable
5adcB-3tixB:
undetectable		 5adcA-3tixB:
21.73
5adcB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.29A 5agnA-3tixB:
undetectable
5agnB-3tixB:
undetectable		 5agnA-3tixB:
21.73
5agnB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 6 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.36A 5fvqA-3tixB:
undetectable
5fvqB-3tixB:
undetectable		 5fvqA-3tixB:
21.73
5fvqB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 6 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.33A 5fvrA-3tixB:
undetectable
5fvrB-3tixB:
undetectable		 5fvrA-3tixB:
21.73
5fvrB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.32A 5fvsA-3tixB:
undetectable
5fvsB-3tixB:
undetectable		 5fvsA-3tixB:
21.73
5fvsB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.36A 5fvtA-3tixB:
undetectable
5fvtB-3tixB:
undetectable		 5fvtA-3tixB:
21.73
5fvtB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.32A 5fvtA-3tixB:
undetectable
5fvtB-3tixB:
undetectable		 5fvtA-3tixB:
21.73
5fvtB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 6 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.38A 5fvuA-3tixB:
undetectable
5fvuB-3tixB:
undetectable		 5fvuA-3tixB:
21.31
5fvuB-3tixB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.32A 5fvwA-3tixB:
undetectable
5fvwB-3tixB:
undetectable		 5fvwA-3tixB:
21.31
5fvwB-3tixB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.34A 5fvxA-3tixB:
undetectable
5fvxB-3tixB:
undetectable		 5fvxA-3tixB:
21.31
5fvxB-3tixB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.32A 5g0nA-3tixB:
undetectable
5g0nB-3tixB:
undetectable		 5g0nA-3tixB:
22.16
5g0nB-3tixB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.30A 5g0nA-3tixB:
undetectable
5g0nB-3tixB:
undetectable		 5g0nA-3tixB:
22.16
5g0nB-3tixB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 3tix UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3
CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe;
Saccharomyces
cerevisiae;
Schizosaccharomy
ces
pombe) 		5 / 11 PRO B 707
ILE B 685
VAL A  66
LEU A  48
THR A  44
 None
None
None
None
CL  A1001 ( 3.9A)
 1.43A 5tiyA-3tixB:
undetectable		 5tiyA-3tixB:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.28A 5untA-3tixB:
undetectable
5untB-3tixB:
undetectable		 5untA-3tixB:
21.73
5untB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.22A 5unwA-3tixB:
undetectable
5unwB-3tixB:
undetectable		 5unwA-3tixB:
21.73
5unwB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.31A 5vulA-3tixB:
undetectable
5vulB-3tixB:
undetectable		 5vulA-3tixB:
21.73
5vulB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.32A 5vumA-3tixB:
undetectable
5vumB-3tixB:
undetectable		 5vumA-3tixB:
21.73
5vumB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.30A 5vunA-3tixB:
undetectable
5vunB-3tixB:
undetectable		 5vunA-3tixB:
21.73
5vunB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.32A 5vupA-3tixB:
undetectable
5vupB-3tixB:
undetectable		 5vupA-3tixB:
21.73
5vupB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.33A 5vuqA-3tixB:
undetectable
5vuqB-3tixB:
undetectable		 5vuqA-3tixB:
21.73
5vuqB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.27A 5vutA-3tixB:
undetectable
5vutB-3tixB:
undetectable		 5vutA-3tixB:
21.73
5vutB-3tixB:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.34A 5vuvA-3tixB:
undetectable
5vuvB-3tixB:
undetectable		 5vuvA-3tixB:
21.31
5vuvB-3tixB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.34A 5vuwA-3tixB:
undetectable
5vuwB-3tixB:
undetectable		 5vuwA-3tixB:
21.31
5vuwB-3tixB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 6 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.32A 5vv0A-3tixB:
1.7
5vv0B-3tixB:
undetectable		 5vv0A-3tixB:
21.51
5vv0B-3tixB:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.30A 5vv2A-3tixB:
undetectable
5vv2B-3tixB:
undetectable		 5vv2A-3tixB:
21.31
5vv2B-3tixB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.31A 5vv3A-3tixB:
undetectable
5vv3B-3tixB:
undetectable		 5vv3A-3tixB:
21.31
5vv3B-3tixB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.34A 6aurA-3tixB:
undetectable
6aurB-3tixB:
undetectable		 6aurA-3tixB:
10.48
6aurB-3tixB:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.30A 6ausA-3tixB:
undetectable
6ausB-3tixB:
undetectable		 6ausA-3tixB:
10.48
6ausB-3tixB:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE B 953
GLU B 951
ARG B 924
VAL B 944
 None
 1.29A 6autA-3tixB:
undetectable
6autB-3tixB:
undetectable		 6autA-3tixB:
10.48
6autB-3tixB:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.28A 6auyA-3tixB:
undetectable
6auyB-3tixB:
undetectable		 6auyA-3tixB:
11.35
6auyB-3tixB:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.31A 6auzA-3tixB:
undetectable
6auzB-3tixB:
undetectable		 6auzA-3tixB:
11.35
6auzB-3tixB:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.27A 6av2A-3tixB:
undetectable
6av2B-3tixB:
undetectable		 6av2A-3tixB:
11.35
6av2B-3tixB:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.33A 6av3A-3tixB:
undetectable
6av3B-3tixB:
undetectable		 6av3A-3tixB:
11.35
6av3B-3tixB:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		4 / 7 ARG B 924
VAL B 944
PHE B 953
GLU B 951
 None
 1.30A 6av4A-3tixB:
undetectable
6av4B-3tixB:
undetectable		 6av4A-3tixB:
11.35
6av4B-3tixB:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 3tix UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3
CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe;
Saccharomyces
cerevisiae;
Schizosaccharomy
ces
pombe) 		3 / 3 TYR B 803
ALA A  65
LEU A  48
 CL  A1002 (-4.9A)
CL  A1002 ( 4.3A)
None
 0.71A 6d9kF-3tixB:
2.3		 6d9kF-3tixB:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
(Schizosaccharomy
ces
pombe) 		3 / 3 TRP B 895
ILE B 897
ASP B 894
 None
 0.84A 6i0y7-3tixB:
undetectable		 6i0y7-3tixB:
4.85