SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tj0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3tj0 NUCLEOPROTEIN
(Influenza
B
virus) 		5 / 12 ILE A 225
GLY A 248
GLY A 246
SER A 231
LEU A 220
 None
 1.10A 1rjdC-3tj0A:
undetectable		 1rjdC-3tj0A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 3tj0 NUCLEOPROTEIN
(Influenza
B
virus) 		5 / 11 ASN A  91
ILE A 108
THR A 367
PRO A 368
ALA A 366
 None
 1.19A 1rv7A-3tj0A:
undetectable
1rv7B-3tj0A:
undetectable		 1rv7A-3tj0A:
12.50
1rv7B-3tj0A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 3tj0 NUCLEOPROTEIN
(Influenza
B
virus) 		3 / 3 GLY A 457
ASP A 456
SER A 477
 None
 0.55A 2qhfA-3tj0A:
undetectable		 2qhfA-3tj0A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 3tj0 NUCLEOPROTEIN
(Influenza
B
virus) 		3 / 3 SER A 507
ARG A 482
GLN A 479
 None
 0.93A 2xnrA-3tj0A:
undetectable		 2xnrA-3tj0A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3tj0 NUCLEOPROTEIN
(Influenza
B
virus) 		4 / 7 THR A 227
PHE A 228
LEU A 215
LEU A 220
 None
 0.79A 3bgdB-3tj0A:
undetectable		 3bgdB-3tj0A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 3tj0 NUCLEOPROTEIN
(Influenza
B
virus) 		5 / 12 GLY A 247
LEU A 317
MET A 321
VAL A 322
ILE A 255
 None
 1.26A 4okbA-3tj0A:
undetectable		 4okbA-3tj0A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3tj0 NUCLEOPROTEIN
(Influenza
B
virus) 		5 / 12 GLN A 109
ALA A 113
TYR A  90
SER A 370
ILE A 371
 None
 1.19A 4pd9A-3tj0A:
undetectable		 4pd9A-3tj0A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 3tj0 NUCLEOPROTEIN
(Influenza
B
virus) 		5 / 12 VAL A 323
VAL A 322
LEU A 296
THR A 227
MET A 504
 None
 1.12A 5bykA-3tj0A:
undetectable		 5bykA-3tj0A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I75_A_68PA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3tj0 NUCLEOPROTEIN
(Influenza
B
virus) 		5 / 12 ILE A 342
SER A 337
GLY A  87
LEU A  86
GLY A 346
 None
 1.18A 5i75A-3tj0A:
undetectable		 5i75A-3tj0A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3tj0 NUCLEOPROTEIN
(Influenza
B
virus) 		4 / 4 TYR A 363
SER A 436
GLN A 440
THR A 406
 None
 1.47A 5n0tB-3tj0A:
0.2		 5n0tB-3tj0A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3tj0 NUCLEOPROTEIN
(Influenza
B
virus) 		4 / 6 ARG A 411
LEU A 384
PHE A 385
PHE A 419
 None
 1.18A 5x19P-3tj0A:
3.4		 5x19P-3tj0A:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 3tj0 NUCLEOPROTEIN
(Influenza
B
virus) 		5 / 12 LEU A 414
VAL A 332
GLY A 548
LEU A 397
PHE A 386
 None
 1.18A 6a7pA-3tj0A:
undetectable		 6a7pA-3tj0A:
20.80