SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 3tj7 GBAA_1210 PROTEIN
(Bacillus
anthracis) 		4 / 7 SER A 138
GLU A 149
GLU A 125
GLU A 151
 None
 1.09A 1knyA-3tj7A:
undetectable
1knyB-3tj7A:
undetectable		 1knyA-3tj7A:
20.69
1knyB-3tj7A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 3tj7 GBAA_1210 PROTEIN
(Bacillus
anthracis) 		4 / 8 GLU A 151
SER A 138
GLU A 149
GLU A 125
 None
 1.12A 1knyA-3tj7A:
undetectable
1knyB-3tj7A:
undetectable		 1knyA-3tj7A:
20.69
1knyB-3tj7A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3tj7 GBAA_1210 PROTEIN
(Bacillus
anthracis) 		5 / 8 LEU A 165
GLN A 168
PHE A 128
LEU A 133
PHE A 135
 None
 1.46A 2dyrC-3tj7A:
undetectable
2dyrJ-3tj7A:
undetectable		 2dyrC-3tj7A:
21.95
2dyrJ-3tj7A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 3tj7 GBAA_1210 PROTEIN
(Bacillus
anthracis) 		5 / 12 LEU A  45
SER A  43
ILE A 108
GLU A  39
LEU A 113
 None
 1.25A 3ko0A-3tj7A:
undetectable
3ko0B-3tj7A:
undetectable
3ko0C-3tj7A:
undetectable
3ko0D-3tj7A:
undetectable		 3ko0A-3tj7A:
19.49
3ko0B-3tj7A:
19.49
3ko0C-3tj7A:
19.49
3ko0D-3tj7A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 3tj7 GBAA_1210 PROTEIN
(Bacillus
anthracis) 		5 / 12 GLU A  39
LEU A 113
LEU A  45
SER A  43
ILE A 108
 None
 1.21A 3ko0K-3tj7A:
undetectable
3ko0L-3tj7A:
undetectable
3ko0M-3tj7A:
undetectable
3ko0N-3tj7A:
undetectable		 3ko0K-3tj7A:
19.49
3ko0L-3tj7A:
19.49
3ko0M-3tj7A:
19.49
3ko0N-3tj7A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 3tj7 GBAA_1210 PROTEIN
(Bacillus
anthracis) 		5 / 12 LEU A  45
SER A  43
ILE A 108
GLU A  39
LEU A 113
 None
 1.19A 3ko0M-3tj7A:
undetectable
3ko0N-3tj7A:
undetectable
3ko0O-3tj7A:
undetectable
3ko0P-3tj7A:
undetectable		 3ko0M-3tj7A:
19.49
3ko0N-3tj7A:
19.49
3ko0O-3tj7A:
19.49
3ko0P-3tj7A:
19.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 3tj7 GBAA_1210 PROTEIN
(Bacillus
anthracis) 		4 / 6 VAL A  34
HIS A  36
SER A 118
THR A 120
 SO4  A 603 ( 4.0A)
SO4  A 603 ( 3.5A)
ACT  A 604 ( 4.9A)
None
 0.13A 3tj7A-3tj7A:
32.3
3tj7B-3tj7A:
29.2		 3tj7A-3tj7A:
100.00
3tj7B-3tj7A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 3tj7 GBAA_1210 PROTEIN
(Bacillus
anthracis) 		3 / 3 LYS A  32
VAL A  34
HIS A  56
 ACT  A 609 (-3.4A)
SO4  A 603 ( 4.0A)
SO4  A 603 (-3.5A)
 0.03A 3tj7A-3tj7A:
32.3		 3tj7A-3tj7A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 3tj7 GBAA_1210 PROTEIN
(Bacillus
anthracis) 		4 / 6 VAL A  34
HIS A  36
SER A 118
THR A 120
 SO4  A 603 ( 4.0A)
SO4  A 603 ( 3.5A)
ACT  A 604 ( 4.9A)
None
 0.10A 3tj7C-3tj7A:
29.8
3tj7D-3tj7A:
28.8		 3tj7C-3tj7A:
100.00
3tj7D-3tj7A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TJ7_C_ACTC608_0
(GBAA_1210 PROTEIN)		 3tj7 GBAA_1210 PROTEIN
(Bacillus
anthracis) 		4 / 5 GLU A   8
LYS A  66
ARG A 123
GLU A 149
 None
 0.91A 3tj7C-3tj7A:
29.8		 3tj7C-3tj7A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 3tj7 GBAA_1210 PROTEIN
(Bacillus
anthracis) 		4 / 6 VAL A  34
HIS A  36
SER A 118
THR A 120
 SO4  A 603 ( 4.0A)
SO4  A 603 ( 3.5A)
ACT  A 604 ( 4.9A)
None
 0.07A 3tj7C-3tj7A:
29.8
3tj7D-3tj7A:
28.8		 3tj7C-3tj7A:
100.00
3tj7D-3tj7A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 3tj7 GBAA_1210 PROTEIN
(Bacillus
anthracis) 		4 / 8 ILE A 171
LEU A 166
LEU A 133
PHE A 128
 None
 0.94A 4qopC-3tj7A:
undetectable		 4qopC-3tj7A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3tj7 GBAA_1210 PROTEIN
(Bacillus
anthracis) 		3 / 3 SER A 138
GLU A 125
GLU A   4
 None
 0.85A 4ymgB-3tj7A:
undetectable		 4ymgB-3tj7A:
22.82