SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tje'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HUO_A_PNNA302_0 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	3tje	FAB E09, HEAVY CHAIN (Homo sapiens)	4 / 6	LEU H 208 GLY H 209 ALA H 144 PRO H 145	None	0.51A	3huoA-3tjeH: undetectable	3huoA-3tjeH: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IOM_A_FOLA608_0 (FORMATE--TETRAHYDROF OLATE LIGASE)	3tje	FAB E09, HEAVY CHAIN (Homo sapiens)	4 / 7	ALA H 74 GLU H 48 TYR H 100 LEU H 89	None EDO H 246 (-3.5A) None None	1.07A	4iomA-3tjeH: undetectable	4iomA-3tjeH: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LV9_B_20JB601_1 (NICOTINAMIDE PHOSPHORIBOSYLTRANSF ERASE)	3tje	FAB E09, HEAVY CHAIN (Homo sapiens)	4 / 7	TYR H 35 SER H 33 ALA H 54 SER H 63	None	1.24A	4lv9A-3tjeH: undetectable 4lv9B-3tjeH: undetectable	4lv9A-3tjeH: 18.82 4lv9B-3tjeH: 18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUM_A_IMNA502_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3tje	FAB E09, HEAVY CHAIN (Homo sapiens)	4 / 7	ILE H 53 ARG H 104 LEU H 4 ILE H 29	None	0.98A	4xumA-3tjeH: undetectable	4xumA-3tjeH: 21.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3HUO_A_PNNA302_0","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","3tje","FAB E09, HEAVY CHAIN","Homo sapiens",4,"LEU H 208;GLY H 209;ALA H 144;PRO H 145","None","0.51A","3huoA-3tjeH:undetectable","3huoA-3tjeH:21.25"],["4IOM_A_FOLA608_0","FORMATE--TETRAHYDROFOLATE LIGASE","3tje","FAB E09, HEAVY CHAIN","Homo sapiens",4,"ALA H  74;GLU H  48;TYR H 100;LEU H  89","None;EDO H 246 (-3.5A);None;None","1.07A","4iomA-3tjeH:undetectable","4iomA-3tjeH:18.80"],["4LV9_B_20JB601_1","NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE;NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE","3tje","FAB E09, HEAVY CHAIN","Homo sapiens",4,"TYR H  35;SER H  33;ALA H  54;SER H  63","None","1.24A","4lv9A-3tjeH:undetectable;4lv9B-3tjeH:undetectable","4lv9A-3tjeH:18.82;4lv9B-3tjeH:18.82"],["4XUM_A_IMNA502_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","3tje","FAB E09, HEAVY CHAIN","Homo sapiens",4,"ILE H  53;ARG H 104;LEU H   4;ILE H  29","None","0.98A","4xumA-3tjeH:undetectable","4xumA-3tjeH:21.02"]]