SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tjr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 10 ALA A  78
PHE A  82
ALA A 125
VAL A 178
ILE A 142
 None
 1.31A 1claA-3tjrA:
undetectable		 1claA-3tjrA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAY_A_ADNA1001_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		7 / 11 GLY A  17
ALA A  19
SER A  20
ASP A  41
ASP A  67
VAL A  68
ALA A  95
 UNL  A 281 ( 3.3A)
UNL  A 281 ( 4.1A)
UNL  A 281 ( 2.6A)
UNL  A 281 ( 2.8A)
UNL  A 281 ( 3.7A)
UNL  A 281 ( 3.6A)
UNL  A 281 ( 3.6A)
 0.52A 1uayA-3tjrA:
26.4		 1uayA-3tjrA:
26.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAY_B_ADNB1002_1
(TYPE II
3-HYDROXYACYL-COA
DEHYDROGENASE)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		7 / 10 GLY A  17
ALA A  19
SER A  20
ASP A  41
ASP A  67
VAL A  68
ALA A  95
 UNL  A 281 ( 3.3A)
UNL  A 281 ( 4.1A)
UNL  A 281 ( 2.6A)
UNL  A 281 ( 2.8A)
UNL  A 281 ( 3.7A)
UNL  A 281 ( 3.6A)
UNL  A 281 ( 3.6A)
 0.54A 1uayB-3tjrA:
26.8		 1uayB-3tjrA:
26.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 GLY A  17
ASP A  41
ASP A  67
ASN A  94
ALA A  95
 UNL  A 281 ( 3.3A)
UNL  A 281 ( 2.8A)
UNL  A 281 ( 3.7A)
UNL  A 281 ( 3.3A)
UNL  A 281 ( 3.6A)
 0.93A 2bm9E-3tjrA:
6.1		 2bm9E-3tjrA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 9 ALA A  78
PHE A  82
LEU A 174
VAL A 178
ILE A 142
 None
 1.34A 3claA-3tjrA:
undetectable		 3claA-3tjrA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		3 / 3 ARG A 203
ILE A 117
THR A 145
 None
UNL  A 281 ( 3.8A)
UNL  A 281 ( 3.8A)
 0.57A 3ia4D-3tjrA:
1.9		 3ia4D-3tjrA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 VAL A  90
LEU A   5
GLY A  10
ALA A  35
LEU A  37
 None
 1.19A 3n8yA-3tjrA:
undetectable		 3n8yA-3tjrA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 ASN A 181
ILE A 142
LEU A 130
GLY A   3
LEU A 134
 None
 0.84A 3uq6A-3tjrA:
7.4		 3uq6A-3tjrA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		4 / 8 TYR A 165
LEU A 103
MET A 106
TRP A 111
 None
 0.95A 3uzzB-3tjrA:
undetectable		 3uzzB-3tjrA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 ASN A 181
ILE A 142
LEU A 130
GLY A   3
LEU A 134
 None
 0.83A 3vaqA-3tjrA:
6.9		 3vaqA-3tjrA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 ASN A 181
ILE A 142
LEU A 130
GLY A   3
LEU A 134
 None
 0.82A 3vasA-3tjrA:
6.4		 3vasA-3tjrA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		4 / 4 SER A 147
ILE A  22
TYR A 160
PRO A 251
 UNL  A 281 ( 2.6A)
UNL  A 281 ( 4.3A)
UNL  A 281 ( 4.7A)
None
 1.46A 4lbxA-3tjrA:
6.6		 4lbxA-3tjrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		4 / 4 SER A 147
ILE A  22
TYR A 160
PRO A 251
 UNL  A 281 ( 2.6A)
UNL  A 281 ( 4.3A)
UNL  A 281 ( 4.7A)
None
 1.45A 4lbxB-3tjrA:
6.2		 4lbxB-3tjrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		4 / 4 SER A 147
ILE A  22
TYR A 160
PRO A 251
 UNL  A 281 ( 2.6A)
UNL  A 281 ( 4.3A)
UNL  A 281 ( 4.7A)
None
 1.45A 4lc4A-3tjrA:
6.6		 4lc4A-3tjrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		4 / 4 SER A 147
ILE A  22
TYR A 160
PRO A 251
 UNL  A 281 ( 2.6A)
UNL  A 281 ( 4.3A)
UNL  A 281 ( 4.7A)
None
 1.47A 4lc4B-3tjrA:
6.5		 4lc4B-3tjrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.29A 4qvlV-3tjrA:
undetectable
4qvlb-3tjrA:
undetectable		 4qvlV-3tjrA:
21.59
4qvlb-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 4qvlH-3tjrA:
undetectable
4qvlN-3tjrA:
undetectable		 4qvlH-3tjrA:
21.59
4qvlN-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 4qvmV-3tjrA:
undetectable
4qvmb-3tjrA:
undetectable		 4qvmV-3tjrA:
21.59
4qvmb-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.27A 4qvmH-3tjrA:
undetectable
4qvmN-3tjrA:
undetectable		 4qvmH-3tjrA:
21.59
4qvmN-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.29A 4qvpV-3tjrA:
undetectable
4qvpb-3tjrA:
undetectable		 4qvpV-3tjrA:
21.59
4qvpb-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
GLY A  23
ALA A 231
 None
UNL  A 281 ( 3.8A)
None
None
None
 1.39A 4qvpV-3tjrA:
undetectable
4qvpb-3tjrA:
undetectable		 4qvpV-3tjrA:
21.59
4qvpb-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 4qvpH-3tjrA:
undetectable
4qvpN-3tjrA:
undetectable		 4qvpH-3tjrA:
21.59
4qvpN-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
GLY A  23
ALA A 231
 None
UNL  A 281 ( 3.8A)
None
None
None
 1.39A 4qvpH-3tjrA:
undetectable
4qvpN-3tjrA:
undetectable		 4qvpH-3tjrA:
21.59
4qvpN-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.29A 4qvqV-3tjrA:
undetectable
4qvqb-3tjrA:
undetectable		 4qvqV-3tjrA:
21.59
4qvqb-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
GLY A  23
ALA A 231
 None
UNL  A 281 ( 3.8A)
None
None
None
 1.39A 4qvqV-3tjrA:
undetectable
4qvqb-3tjrA:
undetectable		 4qvqV-3tjrA:
21.59
4qvqb-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 4qvqH-3tjrA:
undetectable
4qvqN-3tjrA:
undetectable		 4qvqH-3tjrA:
21.59
4qvqN-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
GLY A  23
ALA A 231
 None
UNL  A 281 ( 3.8A)
None
None
None
 1.38A 4qvqH-3tjrA:
undetectable
4qvqN-3tjrA:
undetectable		 4qvqH-3tjrA:
21.59
4qvqN-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 10 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.27A 4qvvV-3tjrA:
0.0
4qvvb-3tjrA:
0.6		 4qvvV-3tjrA:
21.59
4qvvb-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 10 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 4qvvH-3tjrA:
undetectable
4qvvN-3tjrA:
undetectable		 4qvvH-3tjrA:
21.59
4qvvN-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.29A 4qvwV-3tjrA:
undetectable
4qvwb-3tjrA:
undetectable		 4qvwV-3tjrA:
21.59
4qvwb-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.30A 4qvwH-3tjrA:
undetectable
4qvwN-3tjrA:
undetectable		 4qvwH-3tjrA:
21.59
4qvwN-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.27A 4qvyV-3tjrA:
0.0
4qvyb-3tjrA:
undetectable		 4qvyV-3tjrA:
21.59
4qvyb-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.27A 4qvyH-3tjrA:
0.0
4qvyN-3tjrA:
undetectable		 4qvyH-3tjrA:
21.59
4qvyN-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.27A 4qw0V-3tjrA:
undetectable
4qw0b-3tjrA:
undetectable		 4qw0V-3tjrA:
21.59
4qw0b-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.27A 4qw0H-3tjrA:
undetectable
4qw0N-3tjrA:
undetectable		 4qw0H-3tjrA:
21.59
4qw0N-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 4qw1V-3tjrA:
undetectable
4qw1b-3tjrA:
undetectable		 4qw1V-3tjrA:
21.59
4qw1b-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 4qw1H-3tjrA:
undetectable
4qw1N-3tjrA:
undetectable		 4qw1H-3tjrA:
21.59
4qw1N-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.27A 4qw3V-3tjrA:
undetectable
4qw3b-3tjrA:
undetectable		 4qw3V-3tjrA:
21.59
4qw3b-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.27A 4qw3H-3tjrA:
undetectable
4qw3N-3tjrA:
undetectable		 4qw3H-3tjrA:
21.59
4qw3N-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.30A 4qwuV-3tjrA:
undetectable
4qwub-3tjrA:
undetectable		 4qwuV-3tjrA:
21.59
4qwub-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.30A 4qwuH-3tjrA:
undetectable
4qwuN-3tjrA:
undetectable		 4qwuH-3tjrA:
21.59
4qwuN-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		3 / 3 THR A 145
ASN A  94
SER A  93
 UNL  A 281 ( 3.8A)
UNL  A 281 ( 3.3A)
None
 0.37A 4tvtA-3tjrA:
undetectable		 4tvtA-3tjrA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.29A 5bxnV-3tjrA:
undetectable
5bxnb-3tjrA:
undetectable		 5bxnV-3tjrA:
20.83
5bxnb-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 5bxnH-3tjrA:
undetectable
5bxnN-3tjrA:
undetectable		 5bxnH-3tjrA:
20.83
5bxnN-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 9 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 5cz7V-3tjrA:
0.0
5cz7b-3tjrA:
0.0		 5cz7V-3tjrA:
21.59
5cz7b-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 5cz7H-3tjrA:
undetectable
5cz7N-3tjrA:
undetectable		 5cz7H-3tjrA:
21.59
5cz7N-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 5d0xV-3tjrA:
undetectable
5d0xb-3tjrA:
undetectable		 5d0xV-3tjrA:
21.59
5d0xb-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.27A 5d0xH-3tjrA:
undetectable
5d0xN-3tjrA:
undetectable		 5d0xH-3tjrA:
21.59
5d0xN-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 5l5fV-3tjrA:
0.0
5l5fb-3tjrA:
0.6		 5l5fV-3tjrA:
21.59
5l5fb-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.27A 5l5fH-3tjrA:
0.0
5l5fN-3tjrA:
undetectable		 5l5fH-3tjrA:
21.59
5l5fN-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 5l5zV-3tjrA:
undetectable
5l5zb-3tjrA:
undetectable		 5l5zV-3tjrA:
21.59
5l5zb-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 12 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 5l5zH-3tjrA:
undetectable
5l5zN-3tjrA:
undetectable		 5l5zH-3tjrA:
21.59
5l5zN-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 5l66V-3tjrA:
undetectable
5l66b-3tjrA:
undetectable		 5l66V-3tjrA:
21.59
5l66b-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		5 / 11 SER A 230
THR A 145
THR A 238
ALA A 231
THR A 195
 None
UNL  A 281 ( 3.8A)
None
None
UNL  A 281 ( 2.6A)
 1.28A 5l66H-3tjrA:
undetectable
5l66N-3tjrA:
undetectable		 5l66H-3tjrA:
21.59
5l66N-3tjrA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 3tjr SHORT CHAIN
DEHYDROGENASE
(Mycobacterium
avium) 		4 / 6 MET A  74
VAL A  65
LEU A  77
GLN A  44
 None
 1.37A 5xdhA-3tjrA:
undetectable
5xdhC-3tjrA:
undetectable		 5xdhA-3tjrA:
13.24
5xdhC-3tjrA:
13.24