SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tju'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 3tju GRANZYME H
(Homo
sapiens) 		5 / 10 VAL A 157
LEU A 211
GLY A 192
LEU A 159
ILE A  17
 None
 1.36A 1sq5D-3tjuA:
undetectable		 1sq5D-3tjuA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3tju GRANZYME H
(Homo
sapiens) 		5 / 12 ILE A 104
ALA A  57
GLY A 198
VAL A  49
GLY A 209
 None
 1.00A 2qe6B-3tjuA:
undetectable		 2qe6B-3tjuA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_I_SAMI228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3tju GRANZYME H
(Homo
sapiens) 		5 / 12 LYS A  16
GLY A 199
ILE A 210
ALA A  57
ASP A 196
 None
 1.00A 3nvkI-3tjuA:
undetectable		 3nvkI-3tjuA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3tju GRANZYME H
(Homo
sapiens) 		5 / 11 GLY A  46
ALA A  57
GLY A 198
VAL A  33
HIS A  59
 None
 1.44A 4c5lA-3tjuA:
undetectable		 4c5lA-3tjuA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3tju GRANZYME H
(Homo
sapiens) 		5 / 10 GLY A  46
ALA A  57
GLY A 198
VAL A  33
HIS A  59
 None
 1.39A 4c5lC-3tjuA:
undetectable		 4c5lC-3tjuA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3tju GRANZYME H
(Homo
sapiens) 		4 / 6 GLY A 222
PRO A 221
LEU A 159
VAL A 183
 None
 0.91A 4dubB-3tjuA:
undetectable		 4dubB-3tjuA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 3tju GRANZYME H
(Homo
sapiens) 		3 / 3 VAL A 145
SER A 146
THR A 149
 None
 0.46A 4luhA-3tjuA:
undetectable		 4luhA-3tjuA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 3tju GRANZYME H
(Homo
sapiens) 		4 / 6 TRP A 233
ILE A 104
ILE A  65
VAL A  33
 None
 0.86A 4zj8A-3tjuA:
undetectable		 4zj8A-3tjuA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3tju GRANZYME H
(Homo
sapiens) 		5 / 10 LEU A 211
GLY A 198
GLY A  46
VAL A 202
LEU A 201
 None
 1.17A 5o96E-3tjuA:
undetectable
5o96F-3tjuA:
undetectable		 5o96E-3tjuA:
22.96
5o96F-3tjuA:
22.96