SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tjy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3tjy EFFECTOR PROTEIN
HOPAB3
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ALA A 211
ALA A 158
LEU A 178
MET A 166
PHE A 167
 None
 1.16A 1udtA-3tjyA:
undetectable		 1udtA-3tjyA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3tjy EFFECTOR PROTEIN
HOPAB3
(Pseudomonas
syringae
group
genomosp.
3) 		6 / 12 PHE A 167
LEU A 171
ILE A 206
ALA A 205
LEU A 178
MET A 176
 None
 1.44A 2g78A-3tjyA:
undetectable		 2g78A-3tjyA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_B_VIAB902_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3tjy EFFECTOR PROTEIN
HOPAB3
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ALA A 211
ALA A 158
LEU A 178
MET A 166
PHE A 167
 None
 1.07A 2h42B-3tjyA:
undetectable		 2h42B-3tjyA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3tjy EFFECTOR PROTEIN
HOPAB3
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 VAL A 185
PHE A 186
ASN A 162
SER A 179
ASP A 216
 None
 1.22A 2iyfB-3tjyA:
undetectable		 2iyfB-3tjyA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3tjy EFFECTOR PROTEIN
HOPAB3
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 GLN A 188
PHE A 186
PHE A 190
LEU A 204
 None
 1.18A 5b1bC-3tjyA:
undetectable
5b1bJ-3tjyA:
undetectable		 5b1bC-3tjyA:
17.70
5b1bJ-3tjyA:
21.54