SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tl6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 10 ARG A  92
GLU A 183
MET A 184
GLU A 185
ASP A 208
 SO4  A 239 (-3.2A)
None
None
SO4  A 239 ( 4.4A)
None
 0.66A 1jdvA-3tl6A:
33.2
1jdvD-3tl6A:
33.2		 1jdvA-3tl6A:
34.57
1jdvD-3tl6A:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 10 ARG A  92
VAL A 182
GLU A 183
MET A 184
GLU A 185
 SO4  A 239 (-3.2A)
None
None
None
SO4  A 239 ( 4.4A)
 0.23A 1jdvA-3tl6A:
33.2
1jdvD-3tl6A:
33.2		 1jdvA-3tl6A:
34.57
1jdvD-3tl6A:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 10 ARG A  92
GLU A 183
MET A 184
GLU A 185
ASP A 208
 SO4  A 239 (-3.2A)
None
None
SO4  A 239 ( 4.4A)
None
 0.68A 1jdvB-3tl6A:
33.2
1jdvC-3tl6A:
33.3		 1jdvB-3tl6A:
34.57
1jdvC-3tl6A:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 10 ARG A  92
VAL A 182
GLU A 183
MET A 184
GLU A 185
 SO4  A 239 (-3.2A)
None
None
None
SO4  A 239 ( 4.4A)
 0.19A 1jdvB-3tl6A:
33.2
1jdvC-3tl6A:
33.3		 1jdvB-3tl6A:
34.57
1jdvC-3tl6A:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 10 ARG A  92
GLU A 183
MET A 184
GLU A 185
ASP A 208
 SO4  A 239 (-3.2A)
None
None
SO4  A 239 ( 4.4A)
None
 0.64A 1jdvA-3tl6A:
33.2
1jdvD-3tl6A:
33.2		 1jdvA-3tl6A:
34.57
1jdvD-3tl6A:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 10 ARG A  92
VAL A 182
GLU A 183
MET A 184
GLU A 185
 SO4  A 239 (-3.2A)
None
None
None
SO4  A 239 ( 4.4A)
 0.23A 1jdvA-3tl6A:
33.2
1jdvD-3tl6A:
33.2		 1jdvA-3tl6A:
34.57
1jdvD-3tl6A:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		7 / 12 ARG A  92
GLY A  97
GLU A 183
MET A 184
GLU A 185
SER A 207
ASP A 208
 SO4  A 239 (-3.2A)
None
None
None
SO4  A 239 ( 4.4A)
None
None
 0.66A 1jdvE-3tl6A:
33.2
1jdvF-3tl6A:
33.3		 1jdvE-3tl6A:
34.57
1jdvF-3tl6A:
34.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		7 / 12 ARG A  92
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
 SO4  A 239 (-3.2A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.29A 1jdvE-3tl6A:
33.2
1jdvF-3tl6A:
33.3		 1jdvE-3tl6A:
34.57
1jdvF-3tl6A:
34.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		4 / 7 LEU A  22
TYR A  37
TYR A  57
GLY A  55
 None
 0.90A 1lweA-3tl6A:
undetectable		 1lweA-3tl6A:
17.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		6 / 11 ARG A  92
GLY A  97
GLU A 183
MET A 184
GLU A 185
SER A 207
 SO4  A 239 (-3.2A)
None
None
None
SO4  A 239 ( 4.4A)
None
 0.47A 1odiA-3tl6A:
24.9		 1odiA-3tl6A:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		6 / 11 MET A  69
ARG A  92
GLY A  97
GLU A 183
MET A 184
GLU A 185
 None
SO4  A 239 (-3.2A)
None
None
None
SO4  A 239 ( 4.4A)
 0.55A 1odiA-3tl6A:
24.9		 1odiA-3tl6A:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		6 / 11 ARG A  92
GLY A  97
GLU A 183
MET A 184
GLU A 185
SER A 207
 SO4  A 239 (-3.2A)
None
None
None
SO4  A 239 ( 4.4A)
None
 0.46A 1odiB-3tl6A:
33.3		 1odiB-3tl6A:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		6 / 11 MET A  69
ARG A  92
GLY A  97
GLU A 183
MET A 184
GLU A 185
 None
SO4  A 239 (-3.2A)
None
None
None
SO4  A 239 ( 4.4A)
 0.55A 1odiB-3tl6A:
33.3		 1odiB-3tl6A:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		7 / 11 MET A  69
ARG A  92
GLY A  97
GLU A 183
MET A 184
GLU A 185
SER A 207
 None
SO4  A 239 (-3.2A)
None
None
None
SO4  A 239 ( 4.4A)
None
 0.62A 1odiC-3tl6A:
33.3		 1odiC-3tl6A:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		6 / 11 ARG A  92
GLY A  97
GLU A 183
MET A 184
GLU A 185
SER A 207
 SO4  A 239 (-3.2A)
None
None
None
SO4  A 239 ( 4.4A)
None
 0.49A 1odiD-3tl6A:
33.5		 1odiD-3tl6A:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		6 / 11 MET A  69
ARG A  92
GLY A  97
GLU A 183
MET A 184
GLU A 185
 None
SO4  A 239 (-3.2A)
None
None
None
SO4  A 239 ( 4.4A)
 0.57A 1odiD-3tl6A:
33.5		 1odiD-3tl6A:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		7 / 11 MET A  69
ARG A  92
GLY A  97
GLU A 183
MET A 184
GLU A 185
SER A 207
 None
SO4  A 239 (-3.2A)
None
None
None
SO4  A 239 ( 4.4A)
None
 0.60A 1odiE-3tl6A:
33.3		 1odiE-3tl6A:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		7 / 11 MET A  69
ARG A  92
GLY A  97
GLU A 183
MET A 184
GLU A 185
SER A 207
 None
SO4  A 239 (-3.2A)
None
None
None
SO4  A 239 ( 4.4A)
None
 0.62A 1odiF-3tl6A:
33.3		 1odiF-3tl6A:
36.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		9 / 9 MET A  69
ARG A  92
SER A  95
GLY A  97
GLU A 183
MET A 184
GLU A 185
SER A 207
ASP A 208
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
SO4  A 239 ( 4.4A)
None
None
 0.67A 1pk7A-3tl6A:
35.4		 1pk7A-3tl6A:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		7 / 8 ARG A  92
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
 SO4  A 239 (-3.2A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.52A 1pk7B-3tl6A:
35.7		 1pk7B-3tl6A:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		10 / 10 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
ASP A 208
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
None
 0.71A 1pk7C-3tl6A:
35.7		 1pk7C-3tl6A:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		10 / 10 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
ASP A 208
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
None
 0.66A 1pk9A-3tl6A:
35.3		 1pk9A-3tl6A:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 10 MET A 184
ARG A  92
SER A  95
GLU A 185
SER A 207
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
SO4  A 239 ( 4.4A)
None
 1.49A 1pk9A-3tl6A:
35.3		 1pk9A-3tl6A:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		9 / 9 MET A  69
ARG A  92
SER A  95
GLY A  97
GLU A 183
MET A 184
GLU A 185
SER A 207
ASP A 208
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
SO4  A 239 ( 4.4A)
None
None
 0.67A 1pk9B-3tl6A:
35.8		 1pk9B-3tl6A:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		9 / 11 ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
ASP A 208
 SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
None
 0.67A 1pk9C-3tl6A:
35.4		 1pk9C-3tl6A:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		9 / 11 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
ASP A 208
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.70A 1pk9C-3tl6A:
35.4		 1pk9C-3tl6A:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		9 / 10 MET A  69
ARG A  92
SER A  95
GLY A  97
GLU A 183
MET A 184
GLU A 185
SER A 207
ASP A 208
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
SO4  A 239 ( 4.4A)
None
None
 0.68A 1pw7A-3tl6A:
35.4		 1pw7A-3tl6A:
48.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 9 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
 0.44A 1pw7B-3tl6A:
35.9		 1pw7B-3tl6A:
48.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 9 MET A  69
SER A  95
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
ASP A 208
 None
SO4  A 239 (-3.4A)
None
None
None
SO4  A 239 ( 4.4A)
None
None
 0.71A 1pw7C-3tl6A:
35.7		 1pw7C-3tl6A:
48.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 11 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
 0.46A 1vhwA-3tl6A:
35.3
1vhwD-3tl6A:
35.4		 1vhwA-3tl6A:
44.98
1vhwD-3tl6A:
44.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		7 / 9 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
MET A 184
GLU A 185
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
SO4  A 239 ( 4.4A)
 0.48A 1vhwB-3tl6A:
35.4
1vhwF-3tl6A:
35.7		 1vhwB-3tl6A:
44.98
1vhwF-3tl6A:
44.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 11 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
 0.44A 1vhwC-3tl6A:
35.5
1vhwE-3tl6A:
35.2		 1vhwC-3tl6A:
44.98
1vhwE-3tl6A:
44.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 11 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
 0.44A 1vhwA-3tl6A:
35.3
1vhwD-3tl6A:
35.4		 1vhwA-3tl6A:
44.98
1vhwD-3tl6A:
44.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 11 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
 0.46A 1vhwC-3tl6A:
35.5
1vhwE-3tl6A:
35.2		 1vhwC-3tl6A:
44.98
1vhwE-3tl6A:
44.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 10 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
 0.47A 1vhwB-3tl6A:
35.4
1vhwF-3tl6A:
35.7		 1vhwB-3tl6A:
44.98
1vhwF-3tl6A:
44.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 10 MET A  69
ARG A  92
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
 None
SO4  A 239 (-3.2A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.51A 1z35A-3tl6A:
35.5		 1z35A-3tl6A:
45.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 9 MET A  69
ARG A  92
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
 None
SO4  A 239 (-3.2A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.45A 1z37A-3tl6A:
35.2		 1z37A-3tl6A:
45.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 11 MET A  69
ARG A  92
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
ASP A 208
 None
SO4  A 239 (-3.2A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.74A 2ac7A-3tl6A:
35.5
2ac7B-3tl6A:
35.6		 2ac7A-3tl6A:
45.27
2ac7B-3tl6A:
45.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 11 MET A  69
ARG A  92
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
ASP A 208
 None
SO4  A 239 (-3.2A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.75A 2ac7A-3tl6A:
35.5
2ac7B-3tl6A:
35.6		 2ac7A-3tl6A:
45.27
2ac7B-3tl6A:
45.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 10 ILE A  93
PHE A  82
ALA A 188
LEU A 189
ALA A  78
 None
 1.40A 3lw5B-3tl6A:
undetectable		 3lw5B-3tl6A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		3 / 3 TYR A  77
LEU A 236
ARG A  92
 None
None
SO4  A 239 (-3.2A)
 0.70A 3sufB-3tl6A:
undetectable		 3sufB-3tl6A:
21.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		7 / 9 MET A  69
ARG A  92
SER A  95
VAL A 182
GLU A 183
MET A 184
GLU A 185
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
SO4  A 239 ( 4.4A)
 0.26A 3u40A-3tl6A:
42.7
3u40F-3tl6A:
41.2		 3u40A-3tl6A:
100.00
3u40F-3tl6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 10 MET A  69
ARG A  92
SER A  95
VAL A 182
GLU A 183
MET A 184
GLU A 185
CYH A 210
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
SO4  A 239 ( 4.4A)
None
 0.24A 3u40B-3tl6A:
42.0
3u40C-3tl6A:
41.7		 3u40B-3tl6A:
100.00
3u40C-3tl6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		7 / 12 MET A  69
ARG A  92
SER A  95
GLU A 183
MET A 184
GLU A 185
ASP A 208
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
SO4  A 239 ( 4.4A)
None
 0.64A 3u40B-3tl6A:
42.0
3u40C-3tl6A:
41.7		 3u40B-3tl6A:
100.00
3u40C-3tl6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		9 / 12 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
CYH A 210
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.36A 3u40B-3tl6A:
42.0
3u40C-3tl6A:
41.7		 3u40B-3tl6A:
100.00
3u40C-3tl6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		7 / 11 MET A  69
ARG A  92
SER A  95
GLU A 183
MET A 184
GLU A 185
ASP A 208
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
SO4  A 239 ( 4.4A)
None
 0.65A 3u40D-3tl6A:
42.7
3u40E-3tl6A:
42.1		 3u40D-3tl6A:
100.00
3u40E-3tl6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 11 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
 0.25A 3u40D-3tl6A:
42.7
3u40E-3tl6A:
42.1		 3u40D-3tl6A:
100.00
3u40E-3tl6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 12 MET A  69
ARG A  92
SER A  95
GLY A  97
GLU A 183
MET A 184
GLU A 185
ASP A 208
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
SO4  A 239 ( 4.4A)
None
 0.63A 3u40D-3tl6A:
42.7
3u40E-3tl6A:
42.1		 3u40D-3tl6A:
100.00
3u40E-3tl6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		9 / 12 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
CYH A 210
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.28A 3u40D-3tl6A:
42.7
3u40E-3tl6A:
42.1		 3u40D-3tl6A:
100.00
3u40E-3tl6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 10 MET A  69
ARG A  92
SER A  95
VAL A 182
GLU A 183
MET A 184
GLU A 185
ASP A 208
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
SO4  A 239 ( 4.4A)
None
 0.36A 3u40A-3tl6A:
42.7
3u40F-3tl6A:
41.2		 3u40A-3tl6A:
100.00
3u40F-3tl6A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 11 MET A  69
ARG A  92
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
 None
SO4  A 239 (-3.2A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.61A 3uawA-3tl6A:
35.5		 3uawA-3tl6A:
45.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 11 MET A  69
ARG A  92
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
ASP A 208
 None
SO4  A 239 (-3.2A)
None
None
None
SO4  A 239 ( 4.4A)
None
None
 0.80A 3uawA-3tl6A:
35.5		 3uawA-3tl6A:
45.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		7 / 10 MET A  69
ARG A  92
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
 None
SO4  A 239 (-3.2A)
None
None
None
None
SO4  A 239 ( 4.4A)
 0.51A 3uayA-3tl6A:
36.1		 3uayA-3tl6A:
44.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 12 ILE A  90
LEU A 189
ILE A 192
ALA A 193
ILE A  17
 None
 0.70A 3vrmA-3tl6A:
undetectable		 3vrmA-3tl6A:
21.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		10 / 11 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
ASP A 208
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
None
 0.87A 4d9hA-3tl6A:
35.1		 4d9hA-3tl6A:
43.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		6 / 9 MET A  69
GLY A  97
MET A 184
GLU A 185
SER A 207
ASP A 208
 None
None
None
SO4  A 239 ( 4.4A)
None
None
 1.14A 4da6A-3tl6A:
35.2		 4da6A-3tl6A:
43.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		6 / 9 MET A  69
GLY A  97
VAL A 182
MET A 184
GLU A 185
ASP A 208
 None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.97A 4da6A-3tl6A:
35.2		 4da6A-3tl6A:
43.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		6 / 9 MET A  69
SER A  95
GLY A  97
MET A 184
GLU A 185
SER A 207
 None
SO4  A 239 (-3.4A)
None
None
SO4  A 239 ( 4.4A)
None
 0.84A 4da6A-3tl6A:
35.2		 4da6A-3tl6A:
43.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		6 / 9 MET A  69
SER A  95
GLY A  97
VAL A 182
MET A 184
GLU A 185
 None
SO4  A 239 (-3.4A)
None
None
None
SO4  A 239 ( 4.4A)
 0.48A 4da6A-3tl6A:
35.2		 4da6A-3tl6A:
43.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		9 / 10 MET A  69
ARG A  92
GLY A  97
ALA A 161
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
 None
SO4  A 239 (-3.2A)
None
None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.57A 4da7A-3tl6A:
35.0		 4da7A-3tl6A:
43.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		10 / 11 MET A  69
ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
ASP A 208
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
None
 0.93A 4danA-3tl6A:
35.2		 4danA-3tl6A:
43.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 12 ARG A  92
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
ASP A 208
 SO4  A 239 (-3.2A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
None
 0.89A 4danA-3tl6A:
35.2
4danB-3tl6A:
35.3		 4danA-3tl6A:
43.31
4danB-3tl6A:
43.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 12 ARG A  92
SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
 SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.69A 4danA-3tl6A:
35.2
4danB-3tl6A:
35.3		 4danA-3tl6A:
43.31
4danB-3tl6A:
43.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 12 VAL A 143
ILE A 133
GLY A 156
GLY A 113
ILE A 110
 None
 1.05A 4iv0A-3tl6A:
undetectable		 4iv0A-3tl6A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 12 ALA A  78
TYR A  77
SER A  73
GLY A  75
THR A   7
 None
 1.34A 4mm4A-3tl6A:
undetectable		 4mm4A-3tl6A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 12 VAL A 143
ILE A 133
GLY A 156
GLY A 113
ILE A 110
 None
 1.02A 4mwzB-3tl6A:
undetectable		 4mwzB-3tl6A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O79_B_ASCB303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		4 / 6 TYR A 124
ARG A 195
ALA A 194
MET A 191
 None
 1.34A 4o79B-3tl6A:
undetectable		 4o79B-3tl6A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		4 / 6 TYR A 124
ARG A 195
ALA A 194
MET A 191
 None
 1.42A 4o7gB-3tl6A:
undetectable		 4o7gB-3tl6A:
20.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 9 MET A  69
ARG A  92
SER A  95
GLY A  97
ALA A 161
VAL A 182
MET A 184
GLU A 185
 None
SO4  A 239 (-3.2A)
SO4  A 239 (-3.4A)
None
None
None
None
SO4  A 239 ( 4.4A)
 0.49A 5i3cA-3tl6A:
35.7		 5i3cA-3tl6A:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 10 MET A  69
SER A  95
GLY A  97
ALA A 161
VAL A 182
GLU A 183
MET A 184
GLU A 185
 None
SO4  A 239 (-3.4A)
None
None
None
None
None
SO4  A 239 ( 4.4A)
 0.47A 5i3cB-3tl6A:
35.4		 5i3cB-3tl6A:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		8 / 11 MET A  69
GLY A  97
ALA A 161
VAL A 182
GLU A 183
MET A 184
GLU A 185
ASP A 208
 None
None
None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.78A 5i3cC-3tl6A:
35.5		 5i3cC-3tl6A:
48.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		9 / 11 MET A  69
SER A  95
GLY A  97
ALA A 161
VAL A 182
GLU A 183
MET A 184
GLU A 185
SER A 207
 None
SO4  A 239 (-3.4A)
None
None
None
None
None
SO4  A 239 ( 4.4A)
None
 0.49A 5i3cC-3tl6A:
35.5		 5i3cC-3tl6A:
48.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNC_A_QI9A301_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3tl6 PURINE NUCLEOSIDE
PHOSPHORYLASE
(Entamoeba
histolytica) 		5 / 9 SER A  95
GLY A  97
VAL A 182
GLU A 183
MET A 184
 SO4  A 239 (-3.4A)
None
None
None
None
 0.29A 5zncA-3tl6A:
31.6		 5zncA-3tl6A:
28.29