SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tm9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.12A 1gtnB-3tm9A:
undetectable
1gtnC-3tm9A:
undetectable		 1gtnB-3tm9A:
22.70
1gtnC-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.15A 1gtnH-3tm9A:
undetectable
1gtnI-3tm9A:
undetectable		 1gtnH-3tm9A:
22.70
1gtnI-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 11 HIS A  20
ALA A 114
THR A  13
ILE A 106
ALA A 113
 None
 1.11A 1gtnM-3tm9A:
undetectable
1gtnN-3tm9A:
undetectable		 1gtnM-3tm9A:
22.70
1gtnN-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		3 / 3 GLU A 137
VAL A  83
CYH A  86
 None
 1.05A 3fbxA-3tm9A:
undetectable		 3fbxA-3tm9A:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 12 PHE A  28
LEU A 102
TRP A 122
ALA A 125
TYR A 126
 None
None
None
None
HEM  A 201 (-3.5A)
 0.36A 3ozuA-3tm9A:
18.6		 3ozuA-3tm9A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 9 ILE A  24
PHE A  28
ALA A  63
LEU A  62
ALA A 105
 None
 1.01A 3ozvB-3tm9A:
18.5		 3ozvB-3tm9A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		4 / 6 ALA A  64
ILE A 129
LEU A  71
ALA A  77
 HEM  A 201 ( 4.9A)
HEM  A 201 ( 4.6A)
None
None
 0.78A 3r9sC-3tm9A:
undetectable		 3r9sC-3tm9A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		4 / 6 LEU A  42
VAL A  39
VAL A  90
PHE A  28
 HEM  A 201 (-3.9A)
HEM  A 201 ( 4.3A)
HEM  A 201 ( 3.9A)
None
 1.02A 3soaA-3tm9A:
undetectable		 3soaA-3tm9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		8 / 12 THR A  25
PHE A  28
ALA A  56
THR A  60
VAL A  98
LEU A 102
TYR A 126
ILE A 129
 None
None
HEM  A 201 (-3.1A)
HEM  A 201 (-2.5A)
HEM  A 201 (-3.5A)
None
HEM  A 201 (-3.5A)
HEM  A 201 ( 4.6A)
 0.88A 4g1bA-3tm9A:
20.6		 4g1bA-3tm9A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_A_ECNA403_1
(FLAVOHEMOGLOBIN)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		8 / 12 THR A  25
PHE A  28
PHE A  43
ALA A  56
THR A  60
LEU A 102
TYR A 126
ILE A 129
 None
None
HEM  A 201 (-3.1A)
HEM  A 201 (-3.1A)
HEM  A 201 (-2.5A)
None
HEM  A 201 (-3.5A)
HEM  A 201 ( 4.6A)
 1.05A 4g1bA-3tm9A:
20.6		 4g1bA-3tm9A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 11 ILE A  24
THR A  25
PHE A  28
LEU A 102
TYR A 126
 None
None
None
None
HEM  A 201 (-3.5A)
 0.65A 4g1bB-3tm9A:
19.9		 4g1bB-3tm9A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 11 ILE A  24
THR A  25
THR A  60
LEU A 102
TYR A 126
 None
None
HEM  A 201 (-2.5A)
None
HEM  A 201 (-3.5A)
 0.91A 4g1bB-3tm9A:
19.9		 4g1bB-3tm9A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 9 ILE A  24
THR A  25
PHE A  28
VAL A  98
LEU A 102
 None
None
None
HEM  A 201 (-3.5A)
None
 0.65A 4g1bC-3tm9A:
19.9		 4g1bC-3tm9A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		7 / 12 ILE A  24
THR A  25
PHE A  28
PHE A  43
LEU A 102
TYR A 126
ILE A 129
 None
None
None
HEM  A 201 (-3.1A)
None
HEM  A 201 (-3.5A)
HEM  A 201 ( 4.6A)
 0.82A 4g1bD-3tm9A:
19.9		 4g1bD-3tm9A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		7 / 12 ILE A  24
THR A  25
PHE A  43
THR A  60
LEU A 102
TYR A 126
ILE A 129
 None
None
HEM  A 201 (-3.1A)
HEM  A 201 (-2.5A)
None
HEM  A 201 (-3.5A)
HEM  A 201 ( 4.6A)
 1.06A 4g1bD-3tm9A:
19.9		 4g1bD-3tm9A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 12 ILE A  10
GLY A 123
ALA A  58
ILE A  24
VAL A  61
 None
None
None
None
HEM  A 201 ( 3.9A)
 0.84A 4nkxC-3tm9A:
undetectable		 4nkxC-3tm9A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 12 ILE A  10
GLY A 123
ALA A  58
ILE A  24
VAL A  61
 None
None
None
None
HEM  A 201 ( 3.9A)
 0.82A 4nkxD-3tm9A:
undetectable		 4nkxD-3tm9A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.13A 5eeuF-3tm9A:
undetectable
5eeuG-3tm9A:
undetectable		 5eeuF-3tm9A:
22.70
5eeuG-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 12 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.13A 5eeuI-3tm9A:
undetectable
5eeuJ-3tm9A:
undetectable		 5eeuI-3tm9A:
22.70
5eeuJ-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 HIS A  20
ALA A 114
THR A  13
ILE A 106
ALA A 113
 None
 1.16A 5eeuQ-3tm9A:
undetectable
5eeuR-3tm9A:
undetectable		 5eeuQ-3tm9A:
22.70
5eeuR-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.13A 5eevF-3tm9A:
undetectable
5eevG-3tm9A:
undetectable		 5eevF-3tm9A:
22.70
5eevG-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 12 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.13A 5eevI-3tm9A:
undetectable
5eevJ-3tm9A:
undetectable		 5eevI-3tm9A:
22.70
5eevJ-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 HIS A  20
ALA A 114
THR A  13
ILE A 106
ALA A 113
 None
 1.16A 5eevQ-3tm9A:
undetectable
5eevR-3tm9A:
undetectable		 5eevQ-3tm9A:
22.70
5eevR-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.13A 5eewF-3tm9A:
undetectable
5eewG-3tm9A:
undetectable		 5eewF-3tm9A:
22.70
5eewG-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 12 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.13A 5eewI-3tm9A:
undetectable
5eewJ-3tm9A:
undetectable		 5eewI-3tm9A:
22.70
5eewJ-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 HIS A  20
ALA A 114
THR A  13
ILE A 106
ALA A 113
 None
 1.16A 5eewQ-3tm9A:
undetectable
5eewR-3tm9A:
undetectable		 5eewQ-3tm9A:
22.70
5eewR-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.13A 5eexF-3tm9A:
undetectable
5eexG-3tm9A:
undetectable		 5eexF-3tm9A:
22.70
5eexG-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.14A 5eeyF-3tm9A:
undetectable
5eeyG-3tm9A:
undetectable		 5eeyF-3tm9A:
22.70
5eeyG-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.13A 5eezF-3tm9A:
undetectable
5eezG-3tm9A:
undetectable		 5eezF-3tm9A:
22.70
5eezG-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.13A 5ef0F-3tm9A:
undetectable
5ef0G-3tm9A:
undetectable		 5ef0F-3tm9A:
22.70
5ef0G-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.14A 5ef1F-3tm9A:
undetectable
5ef1G-3tm9A:
undetectable		 5ef1F-3tm9A:
22.70
5ef1G-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.14A 5ef2F-3tm9A:
undetectable
5ef2G-3tm9A:
undetectable		 5ef2F-3tm9A:
22.70
5ef2G-3tm9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3tm9 BACTERIAL HEMOGLOBIN
(Vitreoscilla
stercoraria) 		5 / 10 ALA A 113
HIS A  20
ALA A 114
THR A  13
ILE A 106
 None
 1.14A 5ef3F-3tm9A:
undetectable
5ef3G-3tm9A:
undetectable		 5ef3F-3tm9A:
22.70
5ef3G-3tm9A:
22.70