SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tmc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 5 HIS A 183
HIS A 187
HIS A 212
HIS A 237
 FE  A 310 (-3.4A)
PO4  A 311 (-3.9A)
FE  A 309 ( 3.4A)
FE  A 309 (-3.4A)
 0.91A 1e9yB-3tmcA:
undetectable		 1e9yB-3tmcA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 8 ASP A 184
HIS A 183
HIS A 237
HIS A 150
 FE  A 310 (-2.5A)
FE  A 310 (-3.4A)
FE  A 309 (-3.4A)
FE  A 310 ( 3.3A)
 0.58A 1ei6D-3tmcA:
undetectable		 1ei6D-3tmcA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		5 / 11 ALA A 266
HIS A 150
LEU A 176
ALA A 180
HIS A 183
 None
FE  A 310 ( 3.3A)
None
None
FE  A 310 (-3.4A)
 1.33A 1mjlA-3tmcA:
undetectable
1mjlB-3tmcA:
undetectable		 1mjlA-3tmcA:
16.16
1mjlB-3tmcA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 7 MET A 267
ASP A 268
LYS A 145
HIS A 149
 None
DMS  A 312 (-4.0A)
None
DMS  A 312 (-4.0A)
 1.00A 1t03A-3tmcA:
undetectable		 1t03A-3tmcA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		3 / 3 ARG A  43
SER A  64
TYR A  65
 None
 0.54A 1x70A-3tmcA:
undetectable		 1x70A-3tmcA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		5 / 12 LEU A 285
ASP A 268
VAL A 154
HIS A 150
ALA A 258
 None
DMS  A 312 (-4.0A)
None
FE  A 310 ( 3.3A)
None
 1.31A 2g70B-3tmcA:
undetectable		 2g70B-3tmcA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		5 / 9 THR A 272
VAL A 152
THR A 156
ILE A 140
VAL A 137
 DMS  A 312 (-4.3A)
None
None
None
None
 1.20A 2l8mA-3tmcA:
undetectable		 2l8mA-3tmcA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 8 THR A 272
VAL A 154
THR A 153
ILE A 147
 DMS  A 312 (-4.3A)
None
DMS  A 312 (-2.9A)
None
 0.90A 2qbmA-3tmcA:
undetectable		 2qbmA-3tmcA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 6 ASN A 265
SER A 262
ALA A 266
HIS A 293
 FE  A 310 ( 2.6A)
None
None
None
 1.34A 3aruA-3tmcA:
undetectable		 3aruA-3tmcA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		5 / 11 ILE A 214
PRO A 213
LYS A 211
LYS A 247
PRO A 246
 None
 1.29A 3iluB-3tmcA:
undetectable
3iluE-3tmcA:
undetectable		 3iluB-3tmcA:
20.58
3iluE-3tmcA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 7 LEU A 165
VAL A 154
LEU A 157
SER A 158
 None
 0.70A 3r9vA-3tmcA:
undetectable
3r9vB-3tmcA:
undetectable		 3r9vA-3tmcA:
22.29
3r9vB-3tmcA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 5 HIS A 183
HIS A 187
HIS A 212
HIS A 237
 FE  A 310 (-3.4A)
PO4  A 311 (-3.9A)
FE  A 309 ( 3.4A)
FE  A 309 (-3.4A)
 0.95A 4h9mA-3tmcA:
undetectable		 4h9mA-3tmcA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		3 / 3 ARG A   7
GLU A 102
ASN A  98
 None
 0.87A 4imaD-3tmcA:
undetectable		 4imaD-3tmcA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		3 / 3 ARG A   7
GLU A 102
ASN A  98
 None
 0.82A 4ip7D-3tmcA:
undetectable		 4ip7D-3tmcA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		5 / 12 ILE A 214
GLY A 186
GLY A 216
ILE A 147
LEU A 194
 None
None
None
None
PO4  A 311 ( 4.4A)
 1.02A 4mwzA-3tmcA:
undetectable		 4mwzA-3tmcA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		5 / 12 HIS A 237
HIS A 150
LEU A 194
ASP A 184
TRP A 209
 FE  A 309 (-3.4A)
FE  A 310 ( 3.3A)
PO4  A 311 ( 4.4A)
FE  A 310 (-2.5A)
PO4  A 311 (-4.3A)
 1.29A 4r88A-3tmcA:
undetectable		 4r88A-3tmcA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		5 / 6 HIS A 183
HIS A 150
HIS A 187
HIS A 212
HIS A 237
 FE  A 310 (-3.4A)
FE  A 310 ( 3.3A)
PO4  A 311 (-3.9A)
FE  A 309 ( 3.4A)
FE  A 309 (-3.4A)
 1.00A 4ubpC-3tmcA:
undetectable		 4ubpC-3tmcA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB203_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		5 / 9 HIS A 237
GLY A 179
VAL A 261
HIS A 183
ASP A 184
 FE  A 309 (-3.4A)
None
None
FE  A 310 (-3.4A)
FE  A 310 (-2.5A)
 1.43A 5f8yB-3tmcA:
undetectable		 5f8yB-3tmcA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 6 ASP A 184
HIS A 237
HIS A 212
HIS A 150
 FE  A 310 (-2.5A)
FE  A 309 (-3.4A)
FE  A 309 ( 3.4A)
FE  A 310 ( 3.3A)
 0.89A 5ncdA-3tmcA:
undetectable
5ncdD-3tmcA:
undetectable		 5ncdA-3tmcA:
21.83
5ncdD-3tmcA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 6 ASP A 184
HIS A 237
HIS A 212
HIS A 150
 FE  A 310 (-2.5A)
FE  A 309 (-3.4A)
FE  A 309 ( 3.4A)
FE  A 310 ( 3.3A)
 0.92A 5ncdB-3tmcA:
undetectable
5ncdC-3tmcA:
undetectable		 5ncdB-3tmcA:
21.83
5ncdC-3tmcA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		5 / 8 ASP A 184
HIS A 150
HIS A 183
TRP A 209
HIS A 187
 FE  A 310 (-2.5A)
FE  A 310 ( 3.3A)
FE  A 310 (-3.4A)
PO4  A 311 (-4.3A)
PO4  A 311 (-3.9A)
 1.43A 5nekB-3tmcA:
undetectable		 5nekB-3tmcA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 8 ASP A 184
HIS A 237
HIS A 212
HIS A 150
 FE  A 310 (-2.5A)
FE  A 309 (-3.4A)
FE  A 309 ( 3.4A)
FE  A 310 ( 3.3A)
 0.94A 5nekB-3tmcA:
undetectable		 5nekB-3tmcA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		5 / 8 ASP A 184
HIS A 150
HIS A 183
TRP A 209
HIS A 187
 FE  A 310 (-2.5A)
FE  A 310 ( 3.3A)
FE  A 310 (-3.4A)
PO4  A 311 (-4.3A)
PO4  A 311 (-3.9A)
 1.49A 5nekD-3tmcA:
undetectable		 5nekD-3tmcA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 8 ASP A 184
HIS A 237
HIS A 212
HIS A 150
 FE  A 310 (-2.5A)
FE  A 309 (-3.4A)
FE  A 309 ( 3.4A)
FE  A 310 ( 3.3A)
 0.92A 5nekD-3tmcA:
undetectable		 5nekD-3tmcA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 6 ASP A 184
HIS A 237
HIS A 212
HIS A 150
 FE  A 310 (-2.5A)
FE  A 309 (-3.4A)
FE  A 309 ( 3.4A)
FE  A 310 ( 3.3A)
 0.87A 5nelA-3tmcA:
undetectable
5nelD-3tmcA:
undetectable		 5nelA-3tmcA:
21.83
5nelD-3tmcA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 6 HIS A 183
HIS A 237
LEU A 194
HIS A 187
 FE  A 310 (-3.4A)
FE  A 309 (-3.4A)
PO4  A 311 ( 4.4A)
PO4  A 311 (-3.9A)
 1.06A 5nelB-3tmcA:
undetectable
5nelC-3tmcA:
undetectable		 5nelB-3tmcA:
21.83
5nelC-3tmcA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_B_SAMB501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		5 / 12 LEU A 270
ALA A 282
ILE A 271
ASN A 302
LEU A 301
 None
 1.15A 5nfjB-3tmcA:
undetectable		 5nfjB-3tmcA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3tmc UNCHARACTERIZED
PROTEIN
(Bdellovibrio
bacteriovorus) 		5 / 12 LEU A 270
ALA A 282
ILE A 271
ASN A 302
LEU A 301
 None
 1.15A 5nfjC-3tmcA:
undetectable		 5nfjC-3tmcA:
20.72