SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tnq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3tnq CAMP-DEPENDENT
PROTEIN KINASE TYPE
II-BETA REGULATORY
SUBUNIT
(Mus
musculus) 		3 / 3 PRO A 229
ASN A 227
ARG A 247
 None
 0.85A 2qeuB-3tnqA:
undetectable		 2qeuB-3tnqA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N0H_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)		 3tnq CAMP-DEPENDENT
PROTEIN KINASE TYPE
II-BETA REGULATORY
SUBUNIT
(Mus
musculus) 		5 / 11 ILE A 180
ALA A 232
PHE A 219
LEU A 242
VAL A 179
 None
 1.08A 3n0hA-3tnqA:
undetectable		 3n0hA-3tnqA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)		 3tnq CAMP-DEPENDENT
PROTEIN KINASE TYPE
II-BETA REGULATORY
SUBUNIT
(Mus
musculus) 		5 / 12 ILE A 180
ALA A 232
PHE A 219
LEU A 242
VAL A 179
 None
 1.07A 3s3vA-3tnqA:
undetectable		 3s3vA-3tnqA:
18.49