SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tny'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		5 / 12 PHE A 163
ILE A 236
VAL A 247
VAL A 161
ILE A 158
 None
 1.02A 1epbA-3tnyA:
undetectable		 1epbA-3tnyA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		5 / 12 LYS A  59
GLU A  31
VAL A 135
ALA A 268
ALA A 269
 None
 1.22A 1n5xA-3tnyA:
undetectable		 1n5xA-3tnyA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		5 / 12 LYS A  59
GLU A  31
VAL A 135
ALA A 268
ALA A 269
 None
 1.21A 1n5xB-3tnyA:
undetectable		 1n5xB-3tnyA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		4 / 8 THR A 105
GLY A  87
MET A  10
ILE A  85
 None
 0.98A 1rxcI-3tnyA:
undetectable		 1rxcI-3tnyA:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		5 / 12 VAL A  72
LEU A  25
ILE A  85
ILE A 102
ALA A 101
 None
 0.96A 2gj5A-3tnyA:
undetectable		 2gj5A-3tnyA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		4 / 5 ASP A 274
LEU A 273
MET A 143
ARG A 142
 None
 1.27A 2gj5A-3tnyA:
undetectable		 2gj5A-3tnyA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		6 / 12 LEU A  80
VAL A  74
GLY A  87
ILE A  86
VAL A  66
ILE A  77
 None
 1.49A 3bvbA-3tnyA:
undetectable		 3bvbA-3tnyA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6M_A_SPMA501_1
(SPERMINE SYNTHASE)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		5 / 11 TYR A 235
ASP A 167
VAL A 168
TYR A 171
ASP A 257
 None
None
None
SKZ  A 290 (-4.8A)
None
 1.43A 3c6mA-3tnyA:
2.5		 3c6mA-3tnyA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		3 / 3 GLU A 109
GLU A  28
ASN A  88
 None
 0.88A 3lp9B-3tnyA:
undetectable
3lp9D-3tnyA:
undetectable		 3lp9B-3tnyA:
23.47
3lp9D-3tnyA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		5 / 12 GLY A 264
PHE A 176
ASP A 257
TYR A  53
LEU A 272
 None
 1.18A 4a83A-3tnyA:
undetectable		 4a83A-3tnyA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		5 / 10 ALA A  43
PRO A  82
ILE A 102
LEU A  99
ILE A  85
 None
 1.29A 4dtaA-3tnyA:
undetectable		 4dtaA-3tnyA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		4 / 8 THR A 105
GLY A  87
MET A  10
ILE A  85
 None
 0.99A 4e1vE-3tnyA:
2.5		 4e1vE-3tnyA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		4 / 8 THR A 105
GLY A  87
MET A  10
ILE A  85
 None
 1.00A 4e1vH-3tnyA:
undetectable		 4e1vH-3tnyA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		4 / 8 HIS A  92
TYR A 122
ILE A  24
GLU A  69
 None
 1.04A 4ms4A-3tnyA:
3.1		 4ms4A-3tnyA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		4 / 8 SER A 108
HIS A  92
ILE A  24
GLU A  69
 None
 1.22A 4ms4A-3tnyA:
3.1		 4ms4A-3tnyA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		4 / 7 VAL A  63
TRP A  52
ILE A  56
LEU A  25
 None
 1.02A 4xo7B-3tnyA:
undetectable		 4xo7B-3tnyA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		5 / 12 GLU A  69
ARG A  91
VAL A  22
LEU A 126
GLY A  29
 None
SKZ  A 290 (-3.0A)
None
None
None
 1.15A 5vooA-3tnyA:
2.5		 5vooA-3tnyA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3tny YFIY (ABC TRANSPORT
SYSTEM
SUBSTRATE-BINDING
PROTEIN)
(Bacillus
cereus) 		5 / 12 GLU A  69
ARG A  91
VAL A  22
LEU A 126
GLY A  29
 None
SKZ  A 290 (-3.0A)
None
None
None
 1.14A 5vooC-3tnyA:
undetectable		 5vooC-3tnyA:
23.44