SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3to9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3to9 HISTONE
ACETYLTRANSFERASE
ESA1
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 272
VAL A 268
ASP A 269
 None
 0.57A 4y8wC-3to9A:
undetectable		 4y8wC-3to9A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NR3_A_95EA401_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3B)		 3to9 HISTONE
ACETYLTRANSFERASE
ESA1
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 239
PHE A 273
TRP A 247
SER A 255
 None
None
None
ALY  A 262 ( 3.7A)
 1.14A 5nr3A-3to9A:
undetectable		 5nr3A-3to9A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3to9 HISTONE
ACETYLTRANSFERASE
ESA1
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 222
HIS A 284
ARG A 230
 None
SO4  A 508 (-4.3A)
SO4  A 508 (-3.1A)
 1.10A 6b58A-3to9A:
undetectable		 6b58A-3to9A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 3to9 HISTONE
ACETYLTRANSFERASE
ESA1
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 288
LEU A 319
GLY A 317
LEU A 320
 None
None
COA  A 500 (-3.3A)
None
 0.85A 6mdqA-3to9A:
undetectable		 6mdqA-3to9A:
19.75