SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tos'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 8 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 1.01A 1dz9A-3tosA:
undetectable		 1dz9A-3tosA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 3tos CALS11
(Micromonospora
echinospora) 		3 / 3 ASP A 107
ASP A 166
ASP A 189
 SAH  A 258 (-2.7A)
SAH  A 258 (-3.4A)
SAH  A 258 ( 3.6A)
 0.43A 1eizA-3tosA:
10.4		 1eizA-3tosA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 3tos CALS11
(Micromonospora
echinospora) 		3 / 3 ASP A 107
ASP A 166
ASP A 189
 SAH  A 258 (-2.7A)
SAH  A 258 (-3.4A)
SAH  A 258 ( 3.6A)
 0.46A 1ej0A-3tosA:
10.7		 1ej0A-3tosA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWJ_A_CAMA418_0
(CYTOCHROME P450-CAM)		 3tos CALS11
(Micromonospora
echinospora) 		5 / 9 THR A 181
LEU A 175
VAL A 171
VAL A 161
VAL A 163
 None
 1.50A 1iwjA-3tosA:
undetectable		 1iwjA-3tosA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 8 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 1.03A 1o76B-3tosA:
undetectable		 1o76B-3tosA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 1.03A 1t85A-3tosA:
undetectable		 1t85A-3tosA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3tos CALS11
(Micromonospora
echinospora) 		5 / 9 THR A 181
LEU A 175
VAL A 171
VAL A 161
VAL A 163
 None
 1.49A 1t86B-3tosA:
undetectable		 1t86B-3tosA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 8 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.97A 1uyuA-3tosA:
undetectable		 1uyuA-3tosA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3tos CALS11
(Micromonospora
echinospora) 		5 / 10 LEU A 200
ALA A 202
ILE A 203
VAL A 167
PHE A 188
 None
None
None
SAH  A 258 (-3.6A)
None
 0.99A 1xp0A-3tosA:
undetectable		 1xp0A-3tosA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.99A 1yrcA-3tosA:
undetectable		 1yrcA-3tosA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 1.04A 1yrdA-3tosA:
undetectable		 1yrdA-3tosA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3tos CALS11
(Micromonospora
echinospora) 		5 / 12 LEU A 185
ILE A  73
HIS A  83
ASP A 189
GLY A  77
 None
None
SAH  A 258 (-3.4A)
SAH  A 258 ( 3.6A)
SAH  A 258 (-3.4A)
 1.19A 1zz1B-3tosA:
4.1
1zz1C-3tosA:
4.2		 1zz1B-3tosA:
22.25
1zz1C-3tosA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 6 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.97A 2feuA-3tosA:
undetectable		 2feuA-3tosA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.97A 2feuB-3tosA:
undetectable		 2feuB-3tosA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3tos CALS11
(Micromonospora
echinospora) 		3 / 3 ASP A 107
ASP A 166
ASP A 189
 SAH  A 258 (-2.7A)
SAH  A 258 (-3.4A)
SAH  A 258 ( 3.6A)
 0.64A 2igtA-3tosA:
10.8		 2igtA-3tosA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3tos CALS11
(Micromonospora
echinospora) 		3 / 3 ASP A 107
ASP A 166
ASP A 189
 SAH  A 258 (-2.7A)
SAH  A 258 (-3.4A)
SAH  A 258 ( 3.6A)
 0.65A 2igtB-3tosA:
10.8		 2igtB-3tosA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 6 ARG A  91
TYR A  63
THR A  86
ALA A  89
 None
 1.26A 2ql8A-3tosA:
undetectable
2ql8B-3tosA:
undetectable		 2ql8A-3tosA:
20.47
2ql8B-3tosA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_1
(HYPOTHETICAL PROTEIN
TTHA0223)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 5 GLU A  75
ARG A  82
ASP A 107
ASP A 166
 SAH  A 258 (-3.2A)
SAH  A 258 (-3.7A)
SAH  A 258 (-2.7A)
SAH  A 258 (-3.4A)
 0.85A 2yqzA-3tosA:
12.1		 2yqzA-3tosA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_1
(HYPOTHETICAL PROTEIN
TTHA0223)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 5 GLU A  75
ARG A  82
ASP A 107
ASP A 166
 SAH  A 258 (-3.2A)
SAH  A 258 (-3.7A)
SAH  A 258 (-2.7A)
SAH  A 258 (-3.4A)
 0.88A 2yqzB-3tosA:
11.9		 2yqzB-3tosA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 6 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 1.11A 2zuhA-3tosA:
undetectable		 2zuhA-3tosA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 6 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 1.04A 2zuiA-3tosA:
undetectable		 2zuiA-3tosA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 1.02A 2zwtA-3tosA:
undetectable		 2zwtA-3tosA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 1.00A 2zwuA-3tosA:
undetectable		 2zwuA-3tosA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3tos CALS11
(Micromonospora
echinospora) 		5 / 12 LEU A 200
ALA A 202
ILE A 203
VAL A 167
PHE A 188
 None
None
None
SAH  A 258 (-3.6A)
None
 0.98A 3b2rA-3tosA:
undetectable		 3b2rA-3tosA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3tos CALS11
(Micromonospora
echinospora) 		5 / 9 THR A 181
LEU A 175
VAL A 171
VAL A 161
VAL A 163
 None
 1.46A 3cppA-3tosA:
undetectable		 3cppA-3tosA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3tos CALS11
(Micromonospora
echinospora) 		3 / 3 ASP A 107
ASP A 166
ASP A 189
 SAH  A 258 (-2.7A)
SAH  A 258 (-3.4A)
SAH  A 258 ( 3.6A)
 0.42A 3douA-3tosA:
9.6		 3douA-3tosA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.96A 3fwfA-3tosA:
undetectable		 3fwfA-3tosA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.94A 3fwfB-3tosA:
undetectable		 3fwfB-3tosA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 1.03A 3fwiA-3tosA:
undetectable		 3fwiA-3tosA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.99A 3fwjA-3tosA:
undetectable		 3fwjA-3tosA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		5 / 12 GLY A  77
ASP A 107
ASP A 166
ASP A 216
LEU A 190
 SAH  A 258 (-3.4A)
SAH  A 258 (-2.7A)
SAH  A 258 (-3.4A)
EDO  A 261 (-2.7A)
SAH  A 258 (-4.2A)
 0.96A 3iv6B-3tosA:
8.5		 3iv6B-3tosA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.93A 3l63A-3tosA:
undetectable		 3l63A-3tosA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 3tos CALS11
(Micromonospora
echinospora) 		5 / 12 LEU A 190
ASP A 119
GLY A 225
ALA A 229
LEU A 200
 SAH  A 258 (-4.2A)
None
None
None
None
 1.18A 3p5nA-3tosA:
undetectable		 3p5nA-3tosA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 3tos CALS11
(Micromonospora
echinospora) 		5 / 12 LEU A 190
ASP A 119
GLY A 225
ALA A 229
LEU A 200
 SAH  A 258 (-4.2A)
None
None
None
None
 1.16A 3p5nB-3tosA:
1.6		 3p5nB-3tosA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.96A 3wrhA-3tosA:
undetectable		 3wrhA-3tosA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.98A 3wrjA-3tosA:
undetectable		 3wrjA-3tosA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.96A 3wrlA-3tosA:
undetectable		 3wrlA-3tosA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.95A 3wrlE-3tosA:
undetectable		 3wrlE-3tosA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.96A 3wrmA-3tosA:
undetectable		 3wrmA-3tosA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 1.00A 3wrmF-3tosA:
undetectable		 3wrmF-3tosA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		5 / 9 THR A 181
LEU A 175
VAL A 171
VAL A 161
VAL A 163
 None
 1.49A 4ek1B-3tosA:
undetectable		 4ek1B-3tosA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 5 GLY A  77
THR A 196
VAL A 167
ASP A 107
 SAH  A 258 (-3.4A)
None
SAH  A 258 (-3.6A)
SAH  A 258 (-2.7A)
 1.14A 4eohA-3tosA:
5.2		 4eohA-3tosA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 3tos CALS11
(Micromonospora
echinospora) 		3 / 3 ASP A 151
ARG A  91
ASP A 145
 None
 0.73A 4fzvA-3tosA:
undetectable		 4fzvA-3tosA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 VAL A 199
ILE A 203
LEU A  62
LEU A 185
 None
 1.00A 4l1wA-3tosA:
1.9		 4l1wA-3tosA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 8 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.96A 4l4eA-3tosA:
undetectable		 4l4eA-3tosA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 8 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.96A 4l4fA-3tosA:
undetectable		 4l4fA-3tosA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 1.04A 4l4gA-3tosA:
undetectable		 4l4gA-3tosA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 3tos CALS11
(Micromonospora
echinospora) 		3 / 3 LEU A 200
LYS A 197
THR A 196
 None
 0.54A 4lj0A-3tosA:
undetectable		 4lj0A-3tosA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 6 GLY A  77
GLU A  75
ASP A 166
ASP A 189
 SAH  A 258 (-3.4A)
SAH  A 258 (-3.2A)
SAH  A 258 (-3.4A)
SAH  A 258 ( 3.6A)
 1.06A 4uckB-3tosA:
6.6		 4uckB-3tosA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 6 TYR A 193
PRO A 195
LEU A 200
GLU A 201
 None
SAH  A 258 (-4.1A)
None
None
 1.00A 4z4cA-3tosA:
3.1		 4z4cA-3tosA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 TYR A 193
PRO A 195
LEU A 200
GLU A 201
 None
SAH  A 258 (-4.1A)
None
None
 0.99A 4z4fA-3tosA:
undetectable		 4z4fA-3tosA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 TYR A 193
PRO A 195
LEU A 200
GLU A 201
 None
SAH  A 258 (-4.1A)
None
None
 1.01A 5t7bA-3tosA:
3.2		 5t7bA-3tosA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 7 THR A 181
LEU A 175
VAL A 171
VAL A 161
 None
 0.99A 5wk9A-3tosA:
undetectable		 5wk9A-3tosA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 5 ARG A  50
MET A  53
THR A  54
LEU A  57
 None
 1.06A 5x1bW-3tosA:
undetectable		 5x1bW-3tosA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 4 GLY A 105
LEU A  84
VAL A  78
GLU A  75
 None
None
None
SAH  A 258 (-3.2A)
 1.17A 5yw0A-3tosA:
undetectable		 5yw0A-3tosA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3tos CALS11
(Micromonospora
echinospora) 		3 / 3 ASP A 151
ARG A  91
ASP A 145
 None
 0.75A 5zvgA-3tosA:
1.5		 5zvgA-3tosA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3tos CALS11
(Micromonospora
echinospora) 		3 / 3 ASP A 151
ARG A  91
ASP A 145
 None
 0.78A 5zvgB-3tosA:
9.2		 5zvgB-3tosA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3tos CALS11
(Micromonospora
echinospora) 		4 / 5 ARG A  50
MET A  53
THR A  54
LEU A  57
 None
 1.20A 6nknJ-3tosA:
undetectable		 6nknJ-3tosA:
10.90