SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tpa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		4 / 7 PRO A 316
ALA A 468
PHE A 445
PHE A 472
 None
 0.91A 1lqtA-3tpaA:
undetectable		 1lqtA-3tpaA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		4 / 7 PRO A 316
ALA A 468
PHE A 445
PHE A 472
 None
 0.91A 1lquA-3tpaA:
undetectable		 1lquA-3tpaA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		3 / 3 ASN A 475
TRP A 440
GLN A 290
 None
 1.33A 1xoqA-3tpaA:
undetectable		 1xoqA-3tpaA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		3 / 3 THR A 371
PRO A 366
TYR A 306
 None
 0.93A 2dxrA-3tpaA:
2.2		 2dxrA-3tpaA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		4 / 6 THR A  85
PHE A  86
GLN A 172
LEU A 173
 None
 1.17A 3bgdA-3tpaA:
undetectable		 3bgdA-3tpaA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRE_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 9 LEU A 146
VAL A 157
SER A  64
ILE A  63
PHE A  72
 None
 1.02A 3freX-3tpaA:
undetectable		 3freX-3tpaA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		3 / 3 ARG A 204
ILE A  14
THR A 231
 None
 0.74A 3ia4D-3tpaA:
undetectable		 3ia4D-3tpaA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 VAL A  97
VAL A  44
GLY A  56
ALA A  58
LEU A  74
 None
 1.06A 3nt1A-3tpaA:
undetectable		 3nt1A-3tpaA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 VAL A  97
VAL A  44
GLY A  56
ALA A  58
LEU A  74
 None
 1.06A 3nt1B-3tpaA:
undetectable		 3nt1B-3tpaA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 VAL A 142
VAL A  44
GLY A  56
ALA A  58
LEU A  74
 None
 1.20A 3pghA-3tpaA:
undetectable		 3pghA-3tpaA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		3 / 3 THR A 189
ASP A  96
GLU A 168
 None
 0.74A 3qowA-3tpaA:
undetectable		 3qowA-3tpaA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		3 / 3 PHE A 120
LYS A  20
SER A  22
 None
 1.33A 3tyeB-3tpaA:
undetectable		 3tyeB-3tpaA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		4 / 7 ALA A 207
ILE A 193
HIS A  81
GLY A 190
 None
 0.78A 3v4tH-3tpaA:
2.4		 3v4tH-3tpaA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 VAL A  97
VAL A  44
GLY A  56
ALA A  58
LEU A  74
 None
 1.16A 4coxB-3tpaA:
undetectable		 4coxB-3tpaA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 VAL A  97
VAL A  44
GLY A  56
ALA A  58
LEU A  74
 None
 1.16A 4coxC-3tpaA:
undetectable		 4coxC-3tpaA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 VAL A  97
VAL A  44
GLY A  56
ALA A  58
LEU A  74
 None
 1.13A 4rrwA-3tpaA:
undetectable		 4rrwA-3tpaA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 VAL A  97
VAL A  44
GLY A  56
ALA A  58
LEU A  74
 None
 1.13A 4rrwB-3tpaA:
undetectable		 4rrwB-3tpaA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 VAL A  97
VAL A  44
GLY A  56
ALA A  58
LEU A  74
 None
 1.12A 4rrxA-3tpaA:
undetectable		 4rrxA-3tpaA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 VAL A  97
VAL A  44
GLY A  56
ALA A  58
LEU A  74
 None
 1.12A 4rrxB-3tpaA:
undetectable		 4rrxB-3tpaA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 VAL A  97
VAL A  44
GLY A  56
ALA A  58
LEU A  74
 None
 1.13A 4rrzA-3tpaA:
undetectable		 4rrzA-3tpaA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 VAL A  97
VAL A  44
GLY A  56
ALA A  58
LEU A  74
 None
 1.13A 4rrzB-3tpaA:
undetectable		 4rrzB-3tpaA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 GLY A 188
TYR A 165
SER A  35
ASN A  41
TYR A 211
 None
 1.29A 4ymgB-3tpaA:
undetectable		 4ymgB-3tpaA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		4 / 6 SER A 428
GLN A 454
ASP A 418
PRO A 152
 None
 0.91A 5c6pA-3tpaA:
undetectable		 5c6pA-3tpaA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		3 / 3 THR A 189
ASP A  96
GLU A 168
 None
 0.85A 5fa8A-3tpaA:
undetectable		 5fa8A-3tpaA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 VAL A  97
VAL A  44
GLY A  56
ALA A  58
LEU A  74
 None
 1.15A 5ikrA-3tpaA:
undetectable		 5ikrA-3tpaA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 VAL A 142
VAL A  44
GLY A  56
ALA A  58
LEU A  74
 None
 1.21A 5iktB-3tpaA:
undetectable		 5iktB-3tpaA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		5 / 12 VAL A  97
VAL A  44
GLY A  56
ALA A  58
LEU A  74
 None
 1.05A 5jw1A-3tpaA:
undetectable		 5jw1A-3tpaA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		4 / 6 GLY A 190
THR A 189
TYR A 211
ASN A  41
 None
 0.72A 5k4pA-3tpaA:
undetectable		 5k4pA-3tpaA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		4 / 6 PRO A 425
LEU A 271
PHE A 317
LEU A 269
 None
 1.04A 5tl8A-3tpaA:
undetectable		 5tl8A-3tpaA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		4 / 7 ASN A 150
ALA A 453
LYS A 148
LEU A 146
 None
 0.96A 6ci6A-3tpaA:
2.7		 6ci6A-3tpaA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 3tpa HEME-BINDING PROTEIN
A
(Glaesserella
parasuis) 		3 / 3 TRP A 440
ILE A 471
GLU A 443
 None
 0.84A 6hcxA-3tpaA:
undetectable		 6hcxA-3tpaA:
9.77