SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3tpf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3tpf ORNITHINE
CARBAMOYLTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 THR A 219
GLU A 284
HIS A 124
 None
 0.89A 1xwfC-3tpfA:
9.1		 1xwfC-3tpfA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3tpf ORNITHINE
CARBAMOYLTRANSFERASE
(Campylobacter
jejuni) 		3 / 3 THR A 219
GLU A 284
HIS A 124
 None
 0.90A 1xwfD-3tpfA:
8.9		 1xwfD-3tpfA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3tpf ORNITHINE
CARBAMOYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 PHE A  93
LEU A 296
ASP A  92
VAL A  91
PHE A  66
 None
 1.44A 2g70B-3tpfA:
4.3		 2g70B-3tpfA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3tpf ORNITHINE
CARBAMOYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 7 THR A   6
TYR A 123
ILE A 163
ASP A   9
 None
 1.13A 2xytI-3tpfA:
undetectable		 2xytI-3tpfA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3tpf ORNITHINE
CARBAMOYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 8 LYS A  26
ASP A 131
ASP A 220
GLU A 283
 None
 1.04A 2zw9A-3tpfA:
4.3		 2zw9A-3tpfA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3tpf ORNITHINE
CARBAMOYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 11 ALA A 190
PHE A 189
GLY A 169
ALA A 165
VAL A 128
 None
 1.19A 3rukD-3tpfA:
undetectable		 3rukD-3tpfA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 3tpf ORNITHINE
CARBAMOYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 6 ASN A 287
GLY A 130
ASP A 131
ILE A 218
 None
 0.71A 3w9tF-3tpfA:
undetectable		 3w9tF-3tpfA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 3tpf ORNITHINE
CARBAMOYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 5 ILE A 182
ASN A 156
TYR A 123
ILE A 186
 None
 0.95A 4jtpA-3tpfA:
undetectable		 4jtpA-3tpfA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 3tpf ORNITHINE
CARBAMOYLTRANSFERASE
(Campylobacter
jejuni) 		5 / 12 PHE A   4
ILE A 116
LEU A 119
PHE A  53
LEU A  18
 None
 1.06A 5byjA-3tpfA:
undetectable		 5byjA-3tpfA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3tpf ORNITHINE
CARBAMOYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 7 SER A 111
ALA A 108
PRO A 114
MET A   1
 None
 1.10A 5dzkD-3tpfA:
undetectable
5dzkR-3tpfA:
undetectable		 5dzkD-3tpfA:
21.15
5dzkR-3tpfA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 3tpf ORNITHINE
CARBAMOYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 7 LEU A 261
ILE A 135
THR A 134
TRP A 161
 None
 1.26A 5ljcA-3tpfA:
undetectable		 5ljcA-3tpfA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3tpf ORNITHINE
CARBAMOYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 6 ASP A 131
VAL A 128
GLU A 284
ALA A 263
 None
 0.80A 6djzB-3tpfA:
undetectable		 6djzB-3tpfA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3tpf ORNITHINE
CARBAMOYLTRANSFERASE
(Campylobacter
jejuni) 		4 / 7 ILE A 167
LEU A 168
THR A 126
LEU A 129
 None
 0.89A 6nmpA-3tpfA:
undetectable
6nmpJ-3tpfA:
undetectable		 6nmpA-3tpfA:
21.35
6nmpJ-3tpfA:
14.83